Target Malaria is an innovative project that aims to reduce the population of mosquitoes that transmit malaria in sub-Saharan Africa, thereby decreasing disease transmission. As part of its work to combat malaria, Target Malaria has started contained studies at the Uganda Virus Research Institute (U...VRI) in Uganda.
Accessed on 01/07/2025.
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Medicine 2024;103:29(e39010. This review underscores the urgency of adapting to the changing landscape of malaria transmission driven by climate change. It emphasizes the significance of proactively addressing climate-related challenges to enhance malaria control and protect the health and well-bein...g of vulnerable populations.
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Thematic brief. Climate change and malaria are two defining challenges of our generation. Both affect disproportionately the
poorest and the most vulnerable, especially in Africa, and may further jeopardize human wellbeing in the future
The Rectal Artesunate Tools & Training package has been developed to support the safe and effective use of artesunate rectal capsules (ARCs) as a pre-referral treatment for severe malaria, in line with WHO guidelines. Primarily aimed at community health workers operating in remote areas, the package... provides step-by-step visual and written guidance on ARC administration. The training resources were field-tested in Malawi and Senegal, and refined based on user feedback to ensure clarity, usability and cultural appropriateness. The toolkit includes user guides and job aids in English, French and Portuguese, and was created in collaboration with MMV, the WHO, Save the Children, the IFRC, MSF and the Malaria Consortium. These tools form part of broader efforts to integrate ARC into national malaria strategies and strengthen the capacity for an early response in underserved settings.
Accessed on 03/07/2025.
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Older children play a crucial role in preventing malaria by encouraging the use of insecticide-treated bed nets and preventing mosquito breeding. They also support younger children during illness by assisting with nutrition and recovery activities. Recent advancements include the introduction of a m...alaria vaccine in some regions. Educational initiatives empower children to learn, create and share key malaria messages through storytelling, posters and campaigns, thereby fostering community awareness and action.
Accessed July 2025
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This comic book is an educational resource designed to raise awareness of malaria prevention among young people in Burundi. Employing a narrative approach, it features characters who demonstrate key preventive behaviours, such as using insecticide-treated nets, eliminating mosquito breeding sites an...d seeking timely medical treatment. Serving as a tool for community health education, the comic book aims to foster behavioural change and empower children to act as agents of malaria prevention within their families and communities.
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The Malaria Atlas Project (MAP) is a global research initiative that provides high-resolution, evidence-based spatial data on malaria transmission, risk and impact. MAP combines field data, satellite imagery, and advanced geostatistical modelling to deliver open-access maps, datasets, and analytical... tools that support malaria control and elimination strategies worldwide. MAP empowers researchers, policymakers, and public health practitioners by providing them with accurate, up-to-date geographic insights to inform resource allocation and intervention planning.
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The RBM Partnership to End Malaria is a global coalition comprising over 500 partners, including governments, international organisations, the private sector and civil society, who are all dedicated to ending malaria worldwide. Through coordinated advocacy, resource mobilisation and technical suppor...t, the Partnership strengthens national malaria control programmes and accelerates progress towards malaria elimination.
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The Zambia Malaria Campaign, implemented by Breakthrough ACTION, used culturally tailored radio adverts and a campaign song to encourage key behaviours for preventing and treating malaria. The campaign targeted high-risk groups, such as pregnant women and caregivers of children under five, and deliv...ered messages in multiple local languages, including English, Siswati and Tonga. The audio content encouraged the consistent use of insecticide-treated nets (ITNs), seeking timely care for fevers, and preventing malaria during pregnancy. Through addressing common myths and promoting positive social norms in an engaging way, the campaign aimed to increase community knowledge and encourage long-lasting behavioural change in malaria-endemic regions of Zambia.
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Malaria Mini: The Basics is an accredited video course led by Dr John F. Fisher. It provides clinicians with the essential knowledge needed to recognise, prevent and treat malaria. In under an hour, it covers the parasite’s life cycle, transmission, diagnostic methods and the treatment of both unc...omplicated and severe cases. It emphasises practical skills such as taking travel histories and identifying critical symptoms. Designed for flexibility, the course includes quizzes and offers Continuing Medical Education (CME) credits. It is accessible online for free.
Accessed on 17/07/2025.
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This brief, rhythmic video uses a simple, memorable narrative to raise awareness of the dangers of malaria, emphasising how a mosquito bite can lead to serious health problems. The story follows someone who experiences malaria symptoms and seeks free testing and treatment, emphasising the importance... of early diagnosis and prompt medical care. The video's engaging message encourages viewers to avoid risks, get tested and receive appropriate treatment to prevent malaria from worsening.
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A historic funding crisis is threatening to unravel decades of progress unless countries can make radical shifts to HIV programming and funding. The report highlights the impact that the sudden, large-scale funding cuts from international donors are having on countries most affected by HIV. Yet it a...lso showcases some inspiring examples of resilience, with countries and communities stepping up in the face of adversity to protect the gains made and drive the HIV response forward.
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Diabetes poses an increasingly serious health challenge in Africa. Currently, 25 million adults aged 20–79 are living with diabetes, and this figure is projected to increase by 142% to 60 million by 2050 — the highest regional increase worldwide. However, 73% of cases remain undiagnosed, and hea...lthcare spending is the lowest worldwide at just USD 10 billion (1% of global expenditure). In 2024, diabetes caused 216,000 deaths and had a significant impact on maternal health, affecting 1 in 7 births due to hyperglycaemia during pregnancy. Nigeria, Tanzania and the Democratic Republic of the Congo have the highest case loads. Without urgent intervention, the diabetes burden will continue to grow, putting further strain on already limited health systems.
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Since the 1960s, the Tanzanian government has been striving to improve access to quality healthcare, including primary care. However, tuberculosis (TB) remains a significant public health concern, with an estimated prevalence rate of 528 cases per 100,000 people. However, currently, only 36% of TB c...ases are detected, leaving many undiagnosed within the community. Challenges include low community awareness, long distances to diagnostic centres and delayed health-seeking behaviour.
To address these issues, the Ministry of Health (MOHCDGEC) adopted the ENGAGE TB approach, involving NGOs, civil society organisations (CSOs) and other non-state actors in community-based TB activities. This has increased the number of active organisations from five to approximately twenty.
Building on this success, the Ministry has developed national operational guidelines for community-based TB, TB/HIV and drug-resistant TB interventions, with the aim of improving collaboration between communities and health facilities. These guidelines will be updated regularly, and stakeholders are urged to comply fully with them and support TB control efforts.
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Noncommunicable diseases (NCDs) are chronic medical conditions that are not spread from person to person. Unlike infectious diseases, which are caused by bacteria, viruses, or other pathogens, NCDs are typically long-lasting and result from a combination of genetic, physiological, environmental, and... behavioral factors. NCDs are the leading cause of death worldwide and responsible for over 70% of global deaths each year. Over 80% of these deaths occur in low- and middle-income countries (WHO). Noncommunicable diseases pose a serious threat to global health because they are widespread, costly, largely preventable, and responsible for the majority of deaths worldwide. Reducing their impact requires coordinated efforts in prevention, early detection, and healthcare system strengthening, particularly in lower-income countries. The Toolbox on Noncommunicable Diseases (NCDs) can play a vital role in strengthening Global Healthcare systems by providing centralized, reliable, and up-to-date health information and resources like clinical guidlelines, education material as well as tools for prevention and health promotion.
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The handbook is the starting point for anyone interested in learning about and understanding the key principles and concepts of supply chain management for health commodities. Concepts described in this handbook will help those responsible for improving, revising, designing, and operating all or par...t of a supply chain. The addendum provides an overview of health care supply chain management in the humanitarian response context, to help supply chain managers better prepare and deliver to the people who need relief during a crisis.
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La troisième édition du RSI intègre les amendements à l’annexe 7 qui ont été adoptés par la Soixante-Septième Assemblée mondiale de la Santé, par la résolution WHA67.13 (2014). Aux termes de l’annexe 7 modifiée, la durée de la protection conférée par l’administration d’un vacc...in approuvé contre la fièvre jaune, et la validité du certificat de vaccination correspondant, s’étendent à la vie entière du sujet vacciné et ne se limitent plus à 10 ans, comme prévu auparavant.
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Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493
.Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech...anisms underlying Trypanosoma cruzi’s infection and the host-parasite interactions that follow, prompt diagnosis and treatment remain a challenge, particu-larly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
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Background:Neonatal mortality accounts for 43% of global under-five deaths and is decreasing more slowly than maternal or child mortality. Donor funding has increased for maternal, newborn, and child health (MNCH), but no analysis to date has disaggregated aid for newborns. We evaluated if and how a...id flows for newborn care can be tracked, examined changes in the last decade, and considered methodological implications for tracking funding for specific population groups or diseases. MethodsandFindings:We critically reviewed and categorised previous analyses of aid to specific populations, diseases, or types of activities. We then developed and refined key terms related to newborn survival in seven languages and searched titles and descriptions of donor disbursement records in the Organisation for Economic Co-operation and Development’s Creditor Reporting System database, 2002–2010. We compared results with the Countdown to 2015 database of aid for MNCH (2003–2008) and the search strategy used by the Institute for Health Metrics and Evaluation. Prior to 2005, key terms related to newborns were rare in disbursement records but their frequency increased markedly thereafter. Only two mentions were found of ‘‘stillbirth’’ and only nine references were found to ‘‘fetus’’ in any spelling variant or language
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These guidelines form part of efforts to institutionalize the prevention and containment of antimicrobial resistance (AMR) in healthcare facilities in South Africa, as outlined in the Antimicrobial Resistance Strategic Framework and Implementation Plan. The focus of these guidelines is on two interr...elated aspects of prevention of healthcare associated infections (HAIs) and their spread; and the application of antimicrobial stewardship (AMS) practices at hospital level. They aim to serve as a practical, step-by-step or ‘how-to’ guide, addressing the infection prevention and AMS components of a robust response in a hospital. They draw on
evidence from various international guidance documents and standards for interventions that have been shown to be successful in infection
prevention and AMS programmes. These interventions have been customised to the South African hospital setting based on local
experiences in the public and private health sectors. This was done through a series of workshops and requests for comment involving
country-level experts.
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