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Investment Case - Eighth Replenishment 2025 - Executive Summary

The Global Fund (2025) CC

To deliver on the Global Fund Strategy milestones for 2028 and ensure we keep the SDG 3 target within reach, we need to raise US$18 billion to fund the Global Fund’s next three-year grant cycle.

China’s hidden role in malaria control and elimination in Africa

Odhiambo J.N., Dolan C., Malik A.A., et al. BMJ Global Health (2023) CC

Insufficient funding is hindering the achievement of malaria elimination targets in Africa, despite the pressing need for increased investment in malaria control. While Western donors attribute their inaction to financial constraints, the global health community has limited knowledge of China’s ex ... more

Financing global health security: estimating the costs of pandemic preparedness in Global Fund eligible countries

Eaneff S., Boyce M.R., Graeden E., et al. BMJ Global Health (2022) CC

The COVID-19 pandemic demonstrated that the world was not well prepared to respond to an infectious disease threat of this magnitude. Countries across all socioeconomic and development categories have struggled to implement effective national responses. Substantial amounts of additional investmen ... more

Navigating the 2024-2025 Replenishment Era: Strategies for the Global Fund's 8th Replenishment

Roll K., Benn C. Aidspan (2024) CC

The most packed schedule of cyclical replenishments in global health multilateral institutions has the potential to also clash with competing interests fuelled by a packed election calendar. But health imperatives are not a winner gets all scenario. The article provides a perspective on what needs t ... more

Consensus Statement on c-IPTp

RBM Partnership to End Malaria (2024) C2

The Consensus Statement on c-IPTp is a publication by the RBM Partnership to End Malaria. It focuses on community-based intermittent preventive treatment in pregnancy (c-IPTp), aiming to enhance malaria prevention among pregnant women through community-level interventions. The statement offers po ... more

Namibia’s Second Voluntary National Review Report on the Implementation of the Sustainable Development Goals Towards Agenda 2030

National Planning Commission; United Nations Namibia; et al. (2021) CC2

Reflecting its commitment to achieving the Sustainable Development Goals (SDGs), Namibia volunteered to undertake a second national review of the SDGs in 2021. The focus is on three SDG dimensions, namely, Economic, Social, and Environmental. These three dimensions are comprehensively integrated in ... more

Africa’s Health Financing in a New Era

Africa Centres for Disease Control and Prevention (Africa CDC) (2025) CC

Africa’s health sector is facing an unprecedented financing crisis, driven by a sharp decline of 70% in Official Development Assistance (ODA) from 2021 to 2025 and deep-rooted structural vulnerabilities. This collapse is placing immense pressure on Africa’s already fragile health systems as ODA ... is seen as the backbone of critical health programs: pandemic preparedness, maternal and child health services, disease control programs are all at risk, threatening Sustainable Development Goal 3 and Universal Health Coverage. Compounding this is Africa’s spiraling debt, with countries expected to service USD 81 billion by 2025—surpassing anticipated external financing inflows—further eroding fiscal space for health investments. Level of domestic resources is low. TThe Abuja Declaration of 2001, a pivotal commitment made by African Union (AU) member states, aimed to reverse this trend by pledging to allocate at least 15% of national budgets to the health sector. However, more than two decades later, only three countries—Rwanda, Botswana, and Cabo Verde—have consistently met or exceeded this target (WHO, 2023). In contrast, over 30 AU member states remain well below the 10% benchmark, with some allocating as little as 5–7% of their national budgets to health. In addition, only 16 (29%) of African countries currently have updated versions of National Health Development Plan (NHDP) supported by a National Health Financing Plan (NHFP). These two documents play a critical role in driving internal resource mobilisation. At the same time, public health emergencies are surging, rising 41%—from 152 in 2022 to 213 in 2024—exposing severe under-resourcing of health infrastructure and workforce. Recurring outbreaks (Mpox, Ebola, cholera, measles, Marburg…) alongside effects of climate change and humanitarian crises in Eastern DRC, the Sahel, and Sudan, are overwhelming systems stretched by chronic underfunding. The situation is worsened by Africa’s heavy dependency with over 90% of vaccines, medicines, and diagnostics being externally sourced—leaving countries vulnerable to global supply chain shocks. Health worker shortages persist, with only 2.3 professionals per 1,000 people (below the WHO’s recommended 4.45), and fewer than 30% of systems are digitized, undermining disease surveillance and early warning. Without decisive action, Africa CDC projects the continent could reverse two decades of health progress, face 2 to 4 million additional preventable deaths annually, and a heightened risk of a pandemic emerging from within. Furthermore, 39 million more Africans could be pushed into poverty by 2030 due to intertwined health and economic shocks. This is not just a sectoral crisis—it is an existential threat to Africa’s political, social, and economic resilience, and global stability. In response, African leaders, under Africa CDC’s stewardship, are advancing a comprehensive three-pillar strategy centered on domestic resource mobilization, innovative financing, and blended finance. more

Global Health Financing in Turbulent Times: A Detailed Analysis of The Global Fund's Resource Mobilization and Recovery Efforts

Kiai G.N. Aidspan (2024) CC

This article provides an in-depth analysis of the Global Fund's strategic initiatives in resource mobilization and recovery amid global economic fluctuations and geopolitical challenges. It highlights the Fund's successful conversion of pledges and innovative financing models that ensure sustainable ... more

Financing for Sustainable Development Report 2024

Inter-agency Task Force on Financing for Development United Nations (UN) (2024) CC

The world is facing a sustainable development crisis. The 2024 Financing for Sustainable Development Report: Financing for Development at a Crossroads finds that financing challenges are at the heart of the crisis and imperil the SDGs and climate action. The window to rescue the SDGs and prevent a c ... more

Regional Child Protection Operational Note

International Organization for Migration (IOM) (2025) C2

The Regional Child Protection Operational Note has been developed by IOM and UNICEF’s Regional and Country Offices in North, West and Central Africa as a collaborative inter-agency and cross-regional endeavour within the framework of the sixth phase of the IOM Regional Development and Protection P ... more

TB/HIV Coinfection Regional Clinical Manual 2017 Update

Pan American Health Organization PAHO (2018) C_WHO

The purpose of this guide is to provide updated clinical guidance on TB/HIV, with an emphasis on diagnostic aspects—including new techniques—as well as current treatment, while maintaining a public health approach. By compiling and consolidating the latest World Health Organization recommendatio ... more

2025 Global AIDS Update — AIDS, Crisis and the Power to Transform
recommended

UNAIDS (2025) C_WHO

A historic funding crisis is threatening to unravel decades of progress unless countries can make radical shifts to HIV programming and funding. The report highlights the impact that the sudden, large-scale funding cuts from international donors are having on countries most affected by HIV. Yet it a ... more

Prevention and Care for Child Survivors SOP

Child Protection Area of Responsibility; Gender Based Violence Area of Responsibility; Protection Cluster; UN Children's Fund UNICEF; United Nations Population Fund UNFPA (2025) CC

STANDARD OPERATING PROCEDURES - PREVENTION AND CARE FOR CHILD SURVIVORS

Policy Framework for Artificial Intelligence in Tanzania Health Sector

Ministry of Health of the United Republic of Tanzania (2022) C1

The Policy Framework for Artificial Intelligence in Tanzania's Health Sector was developed through collaboration between multiple stakeholders, including government bodies, academic institutions, non-governmental organisations (NGOs) and international partners. The framework demonstrates Tanzania’ ... more

World health statistics 2024: monitoring health for the SDGs, sustainable development goals

World Health Organization WHO (2024) C_WHO

The 2024 edition reviews more than 50 health-related indicators from the Sustainable Development Goals and WHO’s Thirteenth General Programme of Work. It also highlights the findings from the Global health estimates 2021, notably the impact of the COVID-19 pandemic on life expectancy and healthy l ... more

Implementation guidance on counselling women to improve breastfeeding practices

World Health Organization WHO (2025) C_WHO

Breastfeeding is a cornerstone of healthy infant nutrition, development and survival. It is critical for countries* to improve breastfeeding rates in order to achieve global targets for newborn and child health and survival, as well as economic growth and environmental sustainability

MEDBOX Annual Report 2024
recommended

The MEDBOX Team (2025) CC

The MEDBOX Annual Report provides an overview of the most important projects of the past year

National Strategic Plan for the Prevention and Control of Non-Communicable Diseases | 2021 - 2026

Word Health Organization WHO (2021) C_WHO

Non-Communicable Diseases (NCDs) have emerged as conditions of great public health concern in Kenya accounting for 39% of deaths annually. The Ministry of Health through the Department of Non-Communicable Diseases has adopted the vision of achieving a nation free from preventable burden of NCDs. Fur ... more

The intersection of mobility, environmental and climate change, and conflict in the East and Horn of Africa

Brown O. ; Madar S. (Alp Analytica) Mixed Migration Centre MMC (2025) CC

This report synthesizes the state of knowledge on the interlinkages between environmental degradation climate change conflict and mobility in the East and Horn of Africa, focusing on Burundi, Djibouti, Ethiopia, Kenya, Somalia, South Sudan, Tanzania, and Uganda.

Zoonotic Disease: Prevention and Control Strategy 2025-2029
recommended

Africa Center for Disease Control and Prevention CDC (2025) CC

Public health challenges over the past decade have highlighted the importance of approaching health through a holistic lens of human, animal, and environmental sectors, recognizing the need for a collaborative response against shared threats. Zoonotic diseases, transmitted between humans and animals ... more