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Fostering Health Systems’ Monitoring to Better Serve Older Populations

World Health Organisation (WHO) (2023) C_WHO

The chapter Fostering Health Systems’ Monitoring to Better Serve Older Populations is part of the publication series entitled Decade of Healthy Aging: Situation and Challenges. The publications are designed to favor the prioritization of effective actions at the local level as well as the monitori... more

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Analysis of the nature and contribution of innovative health financing mechanisms in the WHO African Region

World Health Organisation (WHO) (2023) C_WHO

Africa is off track to reach the Sustainable Development Goals by 2030 and lags behind in building resilient health systems and health security, against a backdrop of limited resources. The world envisaged a significant role for governments in funding the Sustainable Development Agenda, but inadeq... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Dengue and severe dengue - WHO

World Health Organization WHO (2023) C_WHO

Website last accessed on 31.03.23 Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes causing a potentially lethal complication called severe dengue. The incidence of dengue has increased 30-fold over the last 50 years. Up to 50-100 million infections are ... more

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Challenges and opportunities for primary, secondary, and tertiary prevention of Chagas' disease

Rassi A., Dias J.C.P., Marin-Neto J.a. Heart (2009) C2

A century after its discovery, Chagas' disease still represents a major public health challenge in Latin America. Moreover, because of growing population movements, an increasing number of cases of imported Chagas' disease have now been detected in non-endemic areas, such as North America and some E... more

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Manual for case management of cutaneous leishmaniasis in the WHO Eastern Mediterranean Region

World Health Organization WHO WHO Regional Office for the Eastern Mediterranean (2014) CC

This publication represents a key step forward in translating Control of the leishmaniases (WHO Technical Report Series, No. 949) into a more practical tool for health personnel directly involved in the case management of cutaneous leishmaniasis. With this manual, countries will have, for the first ... more

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Schistosomiasis Key Facts

World Health Organization WHO (2023) C_WHO

Schistosomiasis is an acute and chronic parasitic disease caused by blood flukes (trematode worms) of the genus Schistosoma. Estimates show that at least 251.4 million people required preventive treatment in 2021. Preventive treatment, which should be repeated over a number of years, will reduce and... more

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Fascioliasis animal parasitic disease

Pan American Health Organization PAHO; World Health Organization WHO (2022) C_WHO

Fascioliasis is an animal parasitic disease (in cattle and sheep, but also pigs, donkeys, Llamas and alpacas that can be transmitted to humans. The infection is caught when aquatic or semi-aquatic plants with the larvae of the worm attached to their stem or leaves are ingested raw or poorly cooked. ... more

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Eradicating yaws in Africa: challenges and progress

Tchatchouang, S. The Lancet Microbe (2022) CC

Yaws, a neglected tropical disease (NTD) of the skin caused by the bacterium Treponema pallidum subspecies pertenue, is targeted in the latest WHO NTD Roadmap for eradication by 2030. In January, 2022, WHO published a manual that outlines the key activities that Ministries of Health in endemic count... more

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Film - People, Partnerships, and a Pill: 20 Years of ITI

Stanley, R. Productions International Trachoma Initiative; The Taskforce for Global Health (2018) CC

In 2018, we are celebrating 20 years of progress in eliminating trachoma, the world’s leading infectious cause of blindness. Set up in 1998 by Pfizer Inc. and the Edna McConnell Clark Foundation, the International Trachoma Initiative (ITI) supports Ministries of Health in over 30 countries around ... more

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Rabies & One Health: From basics to cross-sectoral action to stop human rabies deaths

World Health Organization WHO (2022) C_WHO

Rabies is a fatal zoonotic disease most often transmitted to people via bites from infected dogs. This course provides a general introduction to rabies, and the One Health approach currently taken to prevent it. It consists of seven video-lectures, demonstration videos, and lessons learnt from peopl... more

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Rabies a fatal but preventable viral disease

Center for Disease Control and Prevention CDC (2022) CC

Rabies is a fatal but preventable viral disease. It can spread to people and pets if they are bitten or scratched by a rabid animal. In the United States, rabies is mostly found in wild animals like bats, raccoons, skunks, and foxes. However, in many other countries dogs still carry rabies, and most... more

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Philippine Action Plan to Combat AMR: One Health Approach

Phillipine Department of Health (2019) C_WHO

Antibiotics have been useful in fighting infectious diseases in our country for decades, but because of the overuse and misuse of these agents, an increasing number of organisms are now resistant to them. The Philippines, like other Southeast Asian countries, has already been encountering the many c... more

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Core components for IPC - Implementation tools and resources

World Health Organization WHO (2020) C_WHO

Based on scientific evidence, expert consensus and country experiences, the WHO core components for infection prevention and control (IPC) are the foundation for establishing or strengthening effective programmes at the national and facility level. These new guidelines on core components of infecti... more

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The OIE Strategy on Antimicrobial Resistance and the Prudent Use of Antimicrobials

World Organisation for Animal Health (2016) C2

The OIE has been working on the AMR issue for a long time. In undertaking its role as a standard- setting organisation* for animal health, including zoonoses, the OIE has developed a wide range of international standards on antimicrobial agents, in particular on responsible and prudent use. The... more

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Guide to Prudent Use of Antimicrobial Agents in Dairy Production

International Dairy Federation (2013) C2

Antimicrobial agents play an indispensable role in animal health and welfare management. At the same time, the need for prudent use is obvious to ensure good food safety outcomes and to manage the potential risk of antimicrobial resistance. The emergence of multi-resistant bacteria is posing challen... more

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Training and deployment of Key Informants (KIs) for case finding for children with severe visual impairment and blindness and Improving the follow up of children after cataract and other surgeries

Kilimanjaro Centre for Community Ophthalmology KCCO (2022) CC

The WHO estimates that 19 million children aged 15 years or younger are visually impaired. Of these, 1.4 million are irreversibly blind and need visual rehabilitation interventions for full psychological and personal development. The remainder have visual problems that could be prevented or treated.... more

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Manuals, guidelines and toolkits to support the elimination of blinding trachoma

Courtright, P.; MacArthur, C. International Trachoma Initative iTi (2015) CC

The year 2020 is the target date for the elimination of blinding trachoma as a public health problem. There has been great progress, and there is unprecedented funding available – particularly from DFID, the Queen Elizabeth Diamond Jubilee Trust, and USAID. There is also reason for optimism that, ... more

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Report of the 4TH Global Scientific Meeting on Trachoma

World Health Organization WHO (2018) C_WHO

Trachoma is the leading infectious cause of blindness (2). It is characterized by repeated conjunctival infection with particular strains of Chlamydia trachomatis. This scars the conjunctivae and, in some cases, leads to trichiasis with or without entropion. The abrasive action of eyelashes can d... more

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Preventing Child and Maternal Deaths: A Framework for Action in a Changing World 2023-2030

US Agency for International Development USAID (2023) CC

Improving the survival chances and quality of life of women, newborns, and children remains an urgent global challenge. Since 2012, substantial progress has been made in reducing maternal and under-5 deaths, and a only handful of countries are on target to meet the SDG targets in 2030. Yet, 5 millio... more