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Toolboxes
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2
Epidemiology
Chagas disease (American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi, and transmitted to humans by infected triatomine bugs, and less commonly by transfusion, organ transplant, from mother to infant, and in rare instances, by ingestion of contaminated food or
...
drink.1-4 The hematophagous triatomine vectors defecate during or immediately after feeding on a person. The parasite is present in large numbers in the feces of infected bugs, and enters the human body through the bite wound, or through the intact conjunctiva or other mucous membrane.
Vector-borne transmission occurs only in the Americas, where an estimated 8 to 10 million people have Chagas disease.5 Historically, transmission occurred largely in rural areas in Latin America, where houses built of mud brick are vulnerable to colonization by the triatomine vectors.4 In such areas, Chagas disease usually is acquired in childhood. In the last several decades, successful vector control programs have substantially decreased transmission rates in much of Latin America, and large-scale migration has brought infected individuals to cities both within and outside of Latin America.
more
The major neglected tropical diseases, Taenia solium taeniosis/cysticercosis and schistosomiasis caused by Schistosoma mansoni or S. haematobium are presumed to be widely distributed in Africa. Taenia solium taeniosis/ cysticercosis has been reported as an emerging disease in different regions of Af
...
rica [1, 2], but currently the exact distribution remains unclear. Reported prevalences of T. solium taeniosis and cysticercosis in African countries are not extensive and are further complicated by the lack of ‘gold standard’ tests for diagnosis.
more
The Pharmaceutical Forum of the Americas (PFA) has previously published guidelines and organised campaigns for community pharmacists on the prevention, detection and control of arbovirus infections in 2018 with a grant from the FIP Foundation for Pharmacy Education and Research. Building on that exp
...
ertise, FIP joined efforts with the PFA and is now publishing its first-ever handbook to support pharmacists in the
area of vector-borne diseases. As the integration of the regional forums in FIP advances, such collaborative projects are tangible results of an increasingly regionally informed and regionally targeted work by FIP.
more
The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients wit
...
h DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.
more
HIV Treatment Adherence Counseling and Retention Guide
Anderson, L.; J. Jospin, S. Safren, et al.
ICAP Columbia University, and Centers for Disease Control and Prevention CDC
(2024)
C_CDC
A job aid for cadres supporting adolescents living with HIV (ages 15-19) in Orphans and Vulnerable
Children (OVC) Programs
Archives of Medicine vo.7 no.5:10
Individuals infected with human immunodeficiency virus (HIV) often develop
multiple complications and comorbidities, among them, opportunistic infections.
The highest incidence of opportunistic infections was reported in the group
of patients with CD4 lymphocyte
...
levels below 200 cells / mm. Candidiasis,
toxoplasmosis and pneumocystis pneumonia (PCP) were the main representatives.
more
A job aid for cadres supporting caregivers of children and adolescents living with HIV (ages 0-14) in Orphans and Vulnerable Children (OVC) Programs
A Guide for Low Resource Situations
Accessed at March 2014
A finalidade deste documento é apresentar orientações
provisórias para intervenções destinadas a reduzir o risco
de infecção pelo vírus Zika e para tratar potenciais complicações durante a gravidez. Estas orienta ções baseiam-se nas melhores evidências disponíveis da investigação
...
e abrange áreas priorizadas por um grupo
internacional e multidisciplinar de profissionais de saúde e outras partes interessadas. Especificamente, apresenta: orientações para evitar a infecção pelo vírus Zika; cuidados pré-natais e tratamento dasmulherescom infecção;e cuidados durante a gravidez atodas as mulheres grávidas que vivam nas zonas afectadas, com o objectivo de
optimizar os resultados da saúde nas mães e nos recém-nascidos.
more
El objetivo del presente documento consiste en ofrecer
orientaciones provisionales sobre la definición de los casos
de SGB y las estrategias para tratar el síndrome en el
contexto del brote de virus de Zika y de su posible relación
con el SGB. Asimismo, pretende servir como base para la
elab
...
oración de protocolos clínicos y políticas sanitarias
locales relacionadas con la atención a los pacientes con
SGB. En marzo de 2016 se organizará una reunión de
expertos para elaborar más orientaciones sobre la
identificación y el tratamiento del SGB y otros posibles
trastornos neurológicos en el contexto de la transmisión del
virus de Zika.
more
Se espera que sean una referencia para la elaboración de protocolos clínicos y políticas sanitarias a nivel nacional y local relacionados con el embarazo, en el contexto de la transmisión del virus de Zika, pero no se pretende ofrecer una guía práctica completa para la prevención y el tratami
...
ento de esta infección.
more
Il vise à guider l ’ élaboration de protocoles cliniques et de politiques sanitaires à l ’ échelle nationale et locale en ce qui concerne les soins au cours de la grossesse dans le contexte de la transmission du virus Zika. Elles n ’ ont pas pour objectif de fournir un guide pratique exhau
...
stif pour la prévention et la prise en charge des infections à virus Zika.
more
The NGO Safety and Security Training Report provides a narrative of the research findings, an updated curriculum, and guidance tools for training. It is based on extensive research and interviews with members of the NGO community. The report draws upon existing training materials, community consulta
...
tions, survey responses, job descriptions, as well as relevant trends in humanitarian and development practice. It captures good practice and global understanding in regard to quality and consistency of NGO security training.
more
