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Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and annually updated a global strategy for asthma management and prevention that has formed the basis for many national guidelines. However, uptake of existing
...
guidelines is poor. A major revision of the GINA report was published in 2014, and updated in 2015, reflecting an evolving understanding of heterogeneous airways disease, a broader evidence base, increasing interest in targeted treatment, and evidence about effective implementation approaches. During development of the report, the clinical utility of recommendations and strategies for their practical implementation were considered in parallel with the scientific evidence.
more
Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, with airway reversibility. Management of chronic inflammation with anti-asthma medication improves asthma control and quality of li
...
fe. The aim of this journal is to provide an evidence-based approach for chronic asthma management in young children and adolescents and provide guidance on the use of new asthma drugs in children.
For that, the South African Childhood Asthma Working Group (SACAWG) convened in January 2017. The asthma treatment task group reviewed the available scientific literature and international asthma treatment guidelines. The evidence was then graded according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system and recommendations were made based on scientific evidence and local context. Asthma management recommendations were made for children ˂6 years of age and older children and adolescents, as well as for stepping up and stepping down of therapy. This review does not include biologics or novel asthma drugs, which are covered in another CME article in this edition of SAMJ.
The final conclusions are that it is important to ensure good response, treatment and adherence, type of medication, device and checking of technique are all critical. Stepping up of therapy should be done only after ensuring good adherence and technique. Once therapeutic response is achieved, medication administration has to be stepped down to improve ease of use and avoid unnecessary side-effects.
more
Over 90% of the morbidity and mortality related to chronic obstructive pulmonary disease (COPD) and asthma occurs in low-income and middle-income countries (LMICs) due to well documented factors including decreased access to screening, trained health professionals, and therapies for disease
...
management. Inhaler therapy (eg, aerosolised medications by inhalation, nebulisation, or propellant) is the mainstay of treatment for COPD and asthma. Adherence to maintenance medications for COPD and asthma results in improved lung function and quality of life, as well as decreased hospitalisation and mortality. WHO have included short-acting beta-agonists, long-acting muscarinic antagonists, and inhaled corticosteroids on the essential medications list, with a target goal of achieving 80% availability of these medications in public and private facilities. However, despite these efforts, accessibility, and affordability of medications for COPD and asthma remains scarce.
more
The active participation and engagement of health and care workers (HCWs) in health emergency preparedness, readiness and response is crucial to support risk communication, community engagement and infodemic management (RCCE-IM) interven
...
tions during emergencies. HCWs hold unique positions in society – repeatedly being identified among the main influencers of people’s behaviours: they are one of the most trusted sources of health information and advice in communities and role models for the acceptance and uptake of protective measures during health emergencies. On the frontline, HCWs have valuable insights and knowledge that can be harnessed to support health emergencies across the entire emergency cycle. Between October and December 2023, the WHO Regional Office for Europe interviewed key informants on strategies and experiences to meaningfully engage HCWs during emergencies
more
WFP in Namibia collaborated with partners to strategically transition from emergency food relief interventions towards transformative and sustainable food systems assistance. As part of this plan, WFP aims to transfer management of these projects to
...
the Namibian government, thereby contributing to the country's overall food self-sufficiency.
more
Clnical and microbiological predictors of healing in Buruli ulcer disease
Agbavor B.; Agbanyo A.; Loglo A. et al.
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
(2024)
C2
Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH and their
...
use as predictors of time to healing.
more
Clinical and microbiological predictors of healing in Buruli ulcer disease
Agbavor B.; Agbanyo A.; Loglo A. et al.
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
(2024)
C2
Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH and their
...
use as predictors of time to healing.
more
The Zithromax® Supply Chain Assessment Tool is designed to guide assessment team members through a series of interviews
with key informants and to establish inspection procedures when conducting logistics field assessments. The protocol allows
the assessment team to examine the readiness of the N
...
ational Trachoma Control Program and the District- level health
management structures to receive, manage, distribute and administer donated Zithromax® for mass drug administrati
more
The Zithromax® Supply Chain Assessment Tool is designed to guide assessment team members through a series of interviews
with key informants and to establish inspection procedures when conducting logistics field assessments. The protocol allows
the assessment team to examine the readiness of the N
...
ational Trachoma Control Program and the District- level health
management structures to receive, manage, distribute and administer donated Zithromax® for mass drug administrati
more
The Global Programme on Tuberculosis & Lung Health of the World Health Organization (WHO/GTB) is now combining all current recommendations into one overall set of consolidated guidelines on TB. The guidelines contain recommendations pertaining to all areas related to the programmatic
...
management of TB (e.g. screening, preventive treatment, diagnostics, patient support, and the treatment of drug-susceptible TB and DR-TB). The consolidated guidelines contain modules specific to each programmatic area.
more
The "National Guideline for Cholera Surveillance and Outbreak Response" by the Ethiopian Public Health Institute (EPHI) provides a comprehensive approach to combating cholera outbreaks in Ethiopia. It emphasizes the importance of a multisectoral approach, including case
...
management, WASH measures, and the use of cholera vaccines. A key component is the establishment of Cholera Treatment Centers (CTCs) that provide 24/7 care. Additionally, the guideline stresses water quality monitoring and hygiene practices to prevent the spread of cholera and protect public health.
more
This comprehensive HPFM report thoroughly explores Kenya’s health financing landscape. It provides an in-depth analysis of the current state of affairs and sheds light on required strategic changes in health financing. The report points out the need to improve public financial
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management within the health sector, for more efficient financial systems. It focuses on better resourceraising and utilization mechanisms. The matrix highlights the need for consolidation of fragmented health financing arrangements, for a more efficient health system. It also emphasizes the need for enhancing strategic purchasing of health services, to improve the overall efficiency and quality of care. Additionally, the report stresses the critical
role of leveraging data and information systems for more evidence-based informed decision-making. These recommendations are crucial for advancing Kenya’s health financing system and moving closer to the UHC goal.
more
This question bank is a menu of qualitative questions related to healthcare workers’ knowledge, perceptions and practices during infectious disease outbreaks. The question bank will generate qualitative data on healthcare workers’ subjective understandings of risks, case
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management, protection and wider outbreak operations. These data can be used to inform risk communication and community engagement activities as well as other response pillars. Some of the issues covered in these questions are complex, for example stigma or views on vaccine safety
more
In order to improve access to malaria services in remote mining areas of Guyana, the Ministry of Health and PAHO implemented a community case management programme, training workers in mining camps to test for and treat uncomplicated malaria. However
...
, formative research by Breakthrough ACTION Guyana found that awareness of these services among miners was low. In response, the project supported the development of social and behavioural change (SBC) interventions to increase the visibility of volunteer malaria testers (VMTs), strengthen their counselling skills and improve retention by recognising their contributions.
more
The Logistics Cluster (logcluster.org) is a network of humanitarian actors coordinated by the UN (led by the WFP). In the event of disasters, it ensures efficient logistics through coordination, information management and the provision of shared log
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istics services (e.g. transport, storage) in order to speed up the delivery of humanitarian aid and fill gaps in the supply chain
more
The Manual for Indoor Residual Spraying in Urban Areas for Aedes aegypti Control is intended not only for operational personnel and middle and senior management of programs responsible for the prevention and control of Aedes-borne diseases, but also
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for the academic community involved in Aedes research, private pest control personnel, and the general public.
more
This global guidance was developed to support malaria-free countries and those that are close to malaria elimination to prevent re-establishment. The document outlines key concepts and principles for preventing re-establishment and provides guidance on strategies, interventions, planning and
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management. Country examples are included to highlight good practices and illustrate practical applications.
more
Diabetic retinopathy affects over one-third of people with diabetes and is the leading cause of vision loss in working-age adults. Without effective intervention, the number of people with diabetic retinopathy will increase as global diabetes prevalence rises.
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Management and screening for diabetic retinopathy should begin in primary healthcare, where providers play a key role in educating patients, arranging eye examinations and referring patients for treatment if necessary.
more
In line with the Defeating meningitis by 2030: a global road map, the WHO guidelines on meningitis diagnosis, treatment and care Executive Summary provides a summary of the evidence-based recommendations for the clinical management of children and a
...
dults with community-acquired meningitis, including acute and long-term care. Meningitis poses a significant public health threat, despite successful efforts to control the disease globally. The burden of morbidity and mortality from meningitis remains high, particularly in low- and middle-income countries and in settings experiencing large-scale, disruptive epidemics.
more
In this guide, the African Palliative Care Association (APCA) has put together evidence‑based information on the use of specific opioids commonly used in the management of moderate‑to‑severe pain to manage both cancer and non‑cancer pain.
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APCA hopes that this guide will be a useful tool in aiding health professionals at all levels of healthcare delivery to assess and manage pain using opioids. All opioids included in this guide are listed on the WHO model list of essential medicines but we remind readers that oral morphine is the standard opioid of choice for managing moderate‑to‑severe pain and we recommend that it should be made available at all times.
more
