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Version 46 22 Dec 2025. his document provides an overview of malaria rapid diagnostic tests (RDTs) for Principal Recipients (PRs) of Global Fund grants, indicating their eligibility for procurement under the Global Fund's Quality Assurance Policy. The included products have been assessed and approve
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d by the WHO Prequalification of Diagnostics Programme (WHO PQ), the relevant regulatory authorities of the GHTF founding members or the Global Fund Expert Review Panel for Diagnostics (ERPD). Updates are made based on new evidence and regulatory assessments.
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Indicators and questions to monitor progress towards the Global AIDS Strategy 2026-2031 targets
The 2026 outlook remains concerning. Without sustained support, health needs will remain acute. Disease outbreak risks persist amid degraded surveillance. Interagency planning indicates 10.8 million people may be in need, with 4.1 million requiring health assistance. The burden of noncommunicable di
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seases and mental health conditions is expected to worsen. At the same time, international financing for Ukraine’s health response has declined, while humanitarian and health needs remain acute, making sustained support in 2026 critical to prevent further deterioration of essential services.
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The 2026 appeal seeks nearly US$ 1 billion to respond to 36 emergencies worldwide, including 14 Grade 3 emergencies requiring the highest level of organizational response. These emergencies span sudden-onset and protracted humanitarian crises where health needs are critical.
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Recognizing this need and the role of NPHIs in ensuring health security across the continent, the Africa CDC has prioritized the strengthening of NPHIs as a critical pillar of both the New Public Health Order and the Africa CDC Strategic Plan 2023-2027. To aid the realization of this goal, the Afric
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a CDC has developed a Plan for the Development of National Public Health Institutes in Africa 2025-2027. The goal is to ensure that NPHIs are not only present in every Member State but are also empowered with the necessary legal frameworks, resources and expertise to effectively lead Africa’s health security efforts.
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This document assembles these best practices and provides a resource for the proper management of equipment in the laboratory to ensure accurate, reliable and timely testing, and maintain a high level of laboratory performance. Improved equipment management also lowers repair costs, lengthens instru
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L’épidémie de maladie à virus Ebola représente l’une des menaces sanitaires les plus graves pour la santé publique mondiale, en raison de sa létalité élevée, de sa propagation rapide et de ses conséquences sociales, économiques et sécuritaires. L’expérience des 16 précédentes fl
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ambées en République Démocratique du Congo et dans d’autres pays d’Afrique de l’Ouest a montré que la préparation et la réponse rapide sont essentielles pour contenir efficacement la maladie et sauver des vies.
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Sustaining HIV Community-led Responses: Technical guidelines for costing and budgeting
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Community-led responses (CLRs) are a vital pillar of the HIV response and central to achieving national and global targets, including the 30-80-60 commitments outlined in the 2021 Political Declaration on HIV and AIDS. These guidelines provide practical, step-by-step methods for costing and budgetin
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g community-led responses (CLRs), tailored to the unique features of CLRs. They are designed for use by community-led organizations (CLOs), their partners, national governments, policy-makers, donors, and researchers involved in planning, implementing, financing or evaluating CLRs that address HIV.
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The Marburg Virus Disease (MVD) Response Plan outlines Tanzania’s national strategy for responding to a Marburg virus outbreak declared in the Kagera Region in January 2025. The document describes the current epidemiological situation, assesses the risks posed by the outbreak, and sets strategic o
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bjectives to contain the disease and prevent further transmission. It details response measures across multiple sectors, including surveillance, laboratory testing, case management, infection prevention and control, risk communication, logistics, and community engagement. Furthermore, the plan defines coordination mechanisms, operational procedures, monitoring indicators, and the financial resources required to implement the response. Overall, the plan serves as a comprehensive framework to guide national and international stakeholders in controlling the outbreak and protecting public health.
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Filoviral hemorrhagic fever (FHF) is caused by ebolaviruses and marburgviruses, which both belongto the family Filoviridae. Egyptian fruit bats (Rousettus aegyptiacus) are the most likely natural reservoir for marburg viruses and entry into caves and mines that they stay in has often been associated
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with outbreaks of MVD. On the other hand, the natural reservoir for ebola viruses remains elusive;however, handling of wild animal carcasses has been associated with some outbreaks of EVD. In thelast two decades, there has been an increase in the incidence of FHF outbreaks in Africa, some beingcaused by a newly found virus and some occurring in previously unaffected areas such as Guinea, Liberia and Sierra Leone, in which the most recent EVD outbreak occurred in 2014. Indeed, the predicted geographic distribution of filoviruses and their potential reservoirs in Africa includes manycountries in which FHF has not been reported. To minimize the risk of virus dissemination inpreviously unaffected areas, there is a need for increased investment in health infrastructure in African countries, policies to facilitate collaboration between health authorities from different countries, implementation of outbreak control measures by relevant multi-disciplinary teams and education of the populations at risk.
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This review article examines 42 years of Ebola virus disease (EVD) outbreaks in Sub-Saharan Africa, from 1976 to 2019. The authors analyze the epidemiology, geographical distribution, mortality rates, and response strategies associated with 34 Ebola outbreaks across 11 African countries. The review
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