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Chagas Clinical Research Platform

Drugs for Neglected Diseases Initiative DNDi Latin America (2022) CC
To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Chagas disease. The patient-centred platform aims to f... more
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iagnostic Gaps and Recommendations for Human African Trypanosomiasis: Assessment of User Needs, Use Cases, and the Diagnostic Landscape

PATH (2016) C2
In support of the London Declaration goals, PATH aims to catalyze engagement of the diagnostics industry and product development efforts. As part of this work, PATH conducted a diagnostic landscape analysis to identify gaps and evaluated current and nascent HAT diagnostics that may provide solutions... more
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Taenia solium Use of existing diagnostic tools in public health programmes

World Health Organization WHO; Institutional Repository for Information Sharing iris (2022) C_WHO
Taeniasis and cysticercosis caused by the parasite T. solium affect vulnerable populations, mainly in Latin America, sub-Saharan Africa and Asia, where pigs (the intermediate host) roam free and poor sanitation allows pigs access to human faeces.
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Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa

Braae, U.; Saarnak, C.; Mukaratirwa, S. et al. Parasites and Vectors (2015) CC
The major neglected tropical diseases, Taenia solium taeniosis/cysticercosis and schistosomiasis caused by Schistosoma mansoni or S. haematobium are presumed to be widely distributed in Africa. Taenia solium taeniosis/ cysticercosis has been reported as an emerging disease in different regions of Af... more
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Diagnostics to support the eradication of yaws—Development of two target product profiles

Fongwen, N.; Handley, B.; Martin, D. et al. PLoS Neglected Tropical diseases (2022) CC
Yaws is targeted for eradication by 2030, using a strategy based on mass drug administration (MDA) with azithromycin. New diagnostics are needed to aid eradication. Serology is currently the mainstay for yaws diagnosis; however, inaccuracies associated with current serological tests makes it difficu... more
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Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in the Americas

Braae, U.; Thomas, L.; Roberson, L. et al. Parasites and Vectors (2018) CC
Taenia saginata is a zoonotic tapeworm that is of economic importance in countries where cattle are kept. The parasite is transmitted from human tapeworm carriers (taeniosis) to bovines (cysticercosis) by excretion of eggs or proglottids containing eggs into the environment via the stool. Bovines ca... more
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A – Z of Rabies – A guide to the world´s deadliest disease

Mission Rabies (2023) C2
Accessed on 07.03.2023 A – Z of Rabies – A guide to the world´s deadliest disease Mission Rabies
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Philippine Action Plan to Combat AMR: One Health Approach

Phillipine Department of Health (2019) C_WHO
Antibiotics have been useful in fighting infectious diseases in our country for decades, but because of the overuse and misuse of these agents, an increasing number of organisms are now resistant to them. The Philippines, like other Southeast Asian countries, has already been encountering the many c... more
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Clinical utlity of peptide microarrys in the serodiagnosis of neglected tropical diseases in sub-Saharan Africa: protocol for a diagnostic test accuracy sytematic review

Vengesai A., Naicker T., Kasambala M., et al. BMJ Open (2021) C2
Neglected tropical diseases tend to cluster in the same poor populations, and to make progress with their control, they will have to be dealt with in an integrated manner. Peptide microarrays may be a solution to tese problems, where diagnosis for co-infection can be detected simultaneously using th... more
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WHO Guide for Rabies Pre and Post Exposure Prophylaxis in Humans

World Health Organization WHO (2014) C_WHO
WHO strongly recommends discontinuation of the nerve tissue vaccine, and replacement with modern concentrated and purified cell culture derived vaccines (CCDV) and embryonated eggbased rabies vaccines. These vaccines must comply with WHO criteria for potency and innocuity following satisfactory ass... more
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Diagnostic Gaps and Recommendations for Human African Trypanosomiasis: Assessment of User Needs, Use Cases, and the Diagnostic Landscape

Program for Appropriate Technology in Health PATH (2016) C2
This analysis focused on the chronic form of HAT caused by T. b. gambiense, as it contributes to the majority of disease burden. Information from the literature review, product development landscape, and stakeholder interviews was compiled to: - Identify use cases and understand current diagnosti... more
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Epidemiological and clinical aspects of urogenital schistosomiasis in women, in Burkina Faso, West Africa

Zida, A.; Briegel, J.; Kabré, I. et al. BioMed Central (2016) CC
Human schistosomiasis, a parasitic and often chronic illness, is one of the major neglected tropical diseases worldwide. It is estimated that 240 million people suffer from schistosomiasis, with more than 200000 fatalities recorded each year. Schistosomiasis is caused by an infection of the blood fl... more
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Target product profile for a point-of-care diagnostic test for dermal leishmaniases - Control of Neglected Tropical Diseases

World Health Organization WHO (2022) C_WHO
Localized cutaneous leishmaniasis and its evolving forms (diffuse cutaneous leishmaniasis, mucosal leishmaniasis and cutaneous leishmaniasis recidivans), together with the sequela of visceral leishmaniasis (post-kala-azar dermal leishmaniasis), account for about one million cases of dermal leishmani... more
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Chagas Disease: Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV

Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV Clinical Info HIV (2018) CC
Epidemiology Chagas disease (American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi, and transmitted to humans by infected triatomine bugs, and less commonly by transfusion, organ transplant, from mother to infant, and in rare instances, by ingestion of contaminated food or... more
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Guidelines for the Prevention and Treatment of Opportunistic Infections

Clinical Info HIV gov. (2018) CC
Chagas disease (American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi, and transmitted to humans by infected triatomine bugs, and less commonly by transfusion, organ transplant, from mother to infant, and in rare instances, by ingestion of contaminated food or drink.1-4 The... more
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Schistosomiasis (Bilharzia) Frequently Asked Questions

The National Institute for Communicable Diseases (2022) CC
Schistosomiasis, also known as bilharzia, is a disease caused by parasitic worms that require two hosts: humans and certain species of snails. There are two forms of the disease, namely, intestinal schistosomiasis, caused by Schistosoma mansoni and S. japonicum, and urogenital schistosomiasis, cause... more
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Regional Economic Prospects Report (September 2022): A Cold Winter Ahead? - Confronting the energy crunch

European Bank for Reconstruction and Development Reliefweb OCHA Services (2022) C2
EBRD expects Ukraine’s economy to contract by nearly a third in 2022 - EBRD continues to expect Ukraine’s economy to shrink by 30 per cent in 2022 - Bank lowers 2023 GDP growth forecast from 25 per cent to 8 per cent - EBRD Regional Economic Prospects (REP) report highlights war-induced uncer... more
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History, epidemiology and diagnostics of dengue in the American and Brazilian contexts: a review

Souza Salles, T.; T. da Encarnação Sá-Guimarães, E. Seam Lima de Alvarenga et al. (2018) CC
Parasites & Vectors volume 11, Article number: 264 (2018) Dengue creates a staggering epidemiological and economic burden for endemic countries. Without a specific therapy and with a commercial vaccine that presents some problems relative to its full effectiveness, initiatives to improve vector... more
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Epidemiology of dengue in SAARC territory: a systematic review and meta-analysis

Dhan Bahadur Shrestha, Pravash Budhathoki, Bipana Gurung et al. (2022) CC
Parasites & Vectors volume 15, Article number: 389 (2022) Dengue is one of the common arboviral infections and is a public health problem in South East Asia. The aim of this systematic review and meta-analysis was to evaluate the prevalence and distribution of dengue in SAARC (South Asian Associ... more
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Where women have no doctor

A. August Burns, Ronnie Lovich, Jane Maxwell, Katharine Shapiro Hesperian Health Guides (2020) CC
An essential resource that helps a community understand, treat, and prevent many health problems that affect women. Topics include reproductive health, violence, mental health, HIV, and more.