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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Area-Based Assessment with Key Informants - A Practical Guide

UN High Commissioner for Refugees, REACH Initiative (2019) C1

Much remains unknown about displaced communities in out-of-camp areas as identification constraints hinder knowledge on the overall situation and preeminent needs of an area. When compared to regularly monitored in-camp populations, less is known about the health, sanitation, livelihoods, food secur... more

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Public policy challenges in light of the care crisis: The impact of the pandemic on households with children and adolescents led by women

Guzmán M. National Directorate for Economy, Equality and Gender and UNICEF (2021) C_UNICEF

The crisis caused by the COVID-19 pandemic exacerbated preexisting structural economic inequalities, and had a disproportionate impact on informal workers, especially on women and young people, who lost jobs and income. The situation was even more difficult for single-parent households led by women,... more

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Report on the right to freedom of opinion and expression in South Sudan since the July 2016 crisis

UN Office of the High Commissioner for Human Rights, UN Mission in South Sudan (2018)

This report is jointly released by the Human Rights Division (HRD) of the United Nations Mission in South Sudan (UNMISS) and the Office of the United Nations High Commissioner for Human Rights (OHCHR) and focuses on the right to freedom of opinion and expression in South Sudan. It covers the per... more

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Toward Harmonization: Community Health Policy and Program Trends

USAID, JSI Research & Training Institute, fhi360 (2020) CC

The Community Health Systems (CHS) Catalog is a resource that provides information on community health program workers, and interventions for the 25 countries deemed priority by USAID’s Of of Population and Reproductive Health. It comprises a compilation of 25 country profiles developed from a de... more

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COMPENDIUM of health system responses to large-scale migration in the WHO European Region
recommended

World Health Organization WHO, Regional Office for Europe (2018) C_WHO

The scale of international migration in the WHO European Region has increased substantially in the last decade. The dynamics of large-scale migration pose specific challenges and opportunities to health systems, and responses will differ from country to country. Strengthening health system responses... more

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Indonesia: National Action Plan on AMR 2017-2019

Food and Agriculture Organization of the United Nations FAO, World Health Organization WHO and World Organisation for Animal Health OiE (2017) C_WHO

The issue of Antimicrobial resistance has become one of the most substantial health issues, prompting the World Health Assembly (WHA) to urge Member States to finalise tailor made national action plans by May 2017, aligning them with objectives of the Global Action Plan (GAP). These cover awareness,... more

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Bridging the emergency gap

Monica de Castellarnau and Velina Stoianova Médecins Sans Frontières (MSF) (2018) C2

Reflections and a call for action after a two-year exploration of emergency response in acute conflicts
There is general consensus that the humanitarian sector is failing to mount timely and adequate responses in the acute phase of conflict-related emergencies, according to the two-year Emergen... more

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Democratic Republic of the Congo Country Strategic Plan (2021–2024)

World Food Program WFP (2021) CC

Food and nutrition security in the Democratic Republic of the Congo is subject to the relentless impact of conflict, epidemics and climate events that have persisted in the country for decades, further compounded by the global COVID-19 pandemic. Lack of infrastructure and investment in agriculture, ... more

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Protecting Humanitarian Action: Key Challenges and Lessons from the Field

Advanced Training Program on Humanitarian Action ATHA Harvard Humanitarian Initiative (2016) C1

The first section highlights knowledge and questions regarding security incidents, trends, and causes of violence, including around causes and motives for attacks, and tensions between individual and collective responses. The next section then explores the role of the humanitarian principles, and th... more

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Evaluation of Humanitarian Action (EHA). Course Reference Manual

Margie Buchanan-Smith and John Cosgrave Channel Research; ALNAP (2010)

This manual is for the beginner/intermediate and advanced EHA courses run by Channel Research on behalf of ALNAP. It is supported by a course specific set of case studies and exercises and by a bibliography of evaluation references

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The ACT-Accelerator: Two years of impact

World Health Organization WHO (2022) C_WHO

The two-year impact report for the Access to COVID-19 Tools (ACT) Accelerator details impact, case studies and timelines of key milestones for the Diagnostics, Therapeutics and Vaccines pillars, as well as the Health Systems and Response Connector.

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WFP: Inclusive Participation of Persons with Disabilities in Emergency Preparedness and Response Practice Guide (March 2024)

World Food Programme WFP (2024) CC

The World Food Programme (WFP) has taken important steps to progress disability inclusion across its programming and operations. In late 2022, WFP commissioned the Nossal Institute, University of Melbourne in partnership with the Faculty of Psychology, Universitas Gadjah Mada, Indonesia to identify ... more

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Kenya Climate Smart Agriculture Strategy-2017-2026

Ministry of Agriculture, Livestock and Fisheries (2017) CC

Climate Smart Agriculture provides an excellent opportunity for the transformation by uniting agriculture, development and climate change under a common agenda through integrating the three dimensions of sustainable development (economic, social and environmental) by jointly addressing food security... more

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GLI Guide to TB Specimen Referral Systems and Integrated Networks

Global Laboratory Initiative (GLI), Stop TB Partnership (2018) C1

This guide includes information relevant for tuberculosis (TB) program and laboratory managers, as well as Ministry of Health officials across disease programs interested in establishing integrated solutions for specimen referral. Though TB-focused in name, it offers integration-oriented assessment,... more

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Strengthening the collection, analysis and use of health workforce data and information: a handbook

World Health Organisation (WHO) (2023) C_WHO

Access to health workers who are fit for purpose, motivated and protected is a fundamental force of health service delivery and the achievement of universal health coverage and the health and health-related Sustainable Development Goals. Data and knowledge of the distribution, skill mix and future d... more

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Field Trials of Health Interventions: A Toolbox

Peter G. Smith, Richard H. Morrow, and David A. Ross (2015)

This version of Field Trials of Health Interventions includes seven new chapters on conducting systematic literature reviews, trial governance, preliminary studies and pilot testing, budgeting and accounting, intervention costing and economic analysis, and Phase IV studies. Before new interventions... more

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Measuring Resilience: Lessons learned from measuring resilience in Oxfam’s large-N Effectiveness Reviews

Oxfam (2015) C1

Resilience has rapidly become one of the most prominent objectives for the development sector, so ascertaining how best to measure it is an essential task for practioners working in monitoring and evaluation. In this discussion paper, the main insights emerging from the series of large-N Effectivene... more

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India: National Action Plan on Antimicrobial Resistance (NAP-AMR) 2017 – 2021

Ministry of Health & Family Welfare (MoHFW), World Health Organization WHO (2017) C_WHO

The threat posed by antimicrobial resistance (AMR) to public health as well as global health security has been reiterated in umerous World Health Assembly (WHA) resolutions. AMR is also prioritized under the Global Health Security Agenda (GHSA), and India is one of the contributing countries. The Mi... more

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National Action Plan on Antimicrobial Resistance/Afghanistan

Ministry of Public Health, Afghanistan Food and Agriculture Organization of the United Nations FAO (2017) C2

AMR is one of the Key priority of the global health security agenda action package, as well as it is one of the commitments of Ministry of Public Health Afghanistan to combat AMR. In Afghanistan because of war and some other political issues the borders of the country are not well secured and well c... more

COMPENDIUM of health system responses to large-scale migration in the WHO European Region recommended

COMPENDIUM of health system responses to large-scale migration in the WHO European Region
recommended