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This Review summarizes many of the persistent biological alterations associated with childhood maltreatment including changes in neuroendocrine and neurotransmitter systems and pro-inflammatory cytokines in addition to specific alterations in brain areas associated with mood regulation. Finally, I d ... more
Q9. In adults and children with convulsive epilepsy in remission, when should treatment be discontinued?
Q5: What is the added advantage of doing an electroencephalography (EEG) in people with convulsive epilepsy in non- specialist settings in low and middle income countries?

Antiepileptic drug treatment after first unprovoked seizure

World Health Organization (2012) C_WHO
Q8. Should Anti-Epileptic Drug (AED) treatment be started after first unprovoked seizure in non-specialist health settings?
SCOPING QUESTION: In adults with acute convulsive seizures, where intravenous access is available, which first-line anti- epileptic medication should be used to abort seizures when compared to comparator?

Brief psychosocial interventions

World Health Organization (2012) C_WHO
Q1: Are brief psychosocial interventions for people using cannabis or psychostimulants effective in reducing drug use, dependence and harm from drug use?
Ежегодно табак убивает более 7 миллионов человек (1), то есть ежедневно в результате употребления табака или воздействия вторичного табачного дыма (ВТД) умирает бол ... more
Данное руководство разработано в качестве стандартного пособия по оказанию первой психологической помощи для использования в странах с низким и средним уровнем ... more

C.5 Энкопрез

Alexander von Gontard International Association for Child and Adolescent Psychiatry and Allied Professions (2018) C1
Можно выделить две формы энкопреза: энкопрез с запором и без запора. Такое разделение крайне важно, так как в основе этих двух форм лежит разная патофизиология, они ... more
This is an abridged version of the 2019 Standards containing the evidence-based recommendations most pertinent to primary care. The tables and figures have been renum-bered from the original document to match this version. The complete 2019 Standards of Care do ... more
An evidence-informed approach for non-formal, out-of-school CSE programmes that aims to reach young people from left-behind populations This guidance is intended to assist anyone designing and/or implementing CSE in out-of-school settings, especially in low- and middle-income countries. This includ ... more
Nature, biodiversity and health: an overview of interconnections Urbanization, land use, global trade and industrialization have led to profound and negative impacts on nature, biodiversity and ecosystems across the world. The ongoing depletion of natural resources not only affects environmental c ... more
Religion and Development 01/2019. Discussion Paper Series of the Research Programme on Religious Communities and Sustainable Development
The One Health approach can help achieve progress and promotes synergies on national and global priorities by generating synergies at the human-animal-environmental interface. While evidence is still scare, it is likely that the approach is highly cost-effective and improves effectiveness of core pu ... more
Glob Heart . 2020 Oct 13;15(1):69. doi: 10.5334/gh.891.
Los objetivos de las guías son brindar directrices para optimizar el cuidado de la mayoría de los pacientes afectados por los VHB y VHC. Sin embargo, no reemplazan el criterio médico en la valoración y abordaje del paciente individual. En situaciones especiales, el mejor enfoque en el diagnóst ... more
Understanding and addressing violence against women
This global guidance was developed to support malaria-free countries and those that are close to malaria elimination to prevent re-establishment. The document outlines key concepts and principles for preventing re-establishment and provides guidance on strategies, interventions, planning and managem ... more