Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P...lasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
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The right to the enjoyment of the highest attainable standard of physical and mental health is enshrined in many international human rights treaties. However, studies have shown that people with mental disabilities are often marginalized and discriminated against in the fulfillment of their right to... health. The aim of this study is to identify and reach a broader understanding of barriers to the right to mental health in the Eastern Cape Province in South Africa. Eleven semi-structured interviews were carried out with health professionals and administrators.
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A community-based approach.
These guidelines focus on manmade rather than natural disasters, but our experiences in India, El Salvador and Pakistan (earthquake interventions), and following the 2004 tsunami, cyclone Nargis in 2008 and the Haiti earthquake in 2010, showed that the principles describ...ed also work well in contexts of natural disasters.
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In the present study, the Office of the United Nations High Commissioner for Human Rights sets forth the standards on equality and non discrimination of persons with disabilities under article 5 of the Convention on the Rights of Persons with Disabilities. It aims at providing guidance for implement...ation of article 5 of the Convention, identifying good practices and making recommendations.
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The objective of this project was to list the medical devices required to provide the essential reproductive, maternal, newborn and child health interventions defined by existing WHO guidelines and publications, in order to improve access to these devices in low- and middle-income countries, support... quality of care, and strengthen health-care system. The medical devices are allocated across the reproductive, maternal, newborn and child health continuum of care according to the level of health-care delivery.
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Le Profil Pays constitue donc un document de référence pour tout chercheur, praticien et acteur intéressé par la planification familiale en général et par les besoins non satisfaits en particulier. Il fournit de précieux éclairages pour le renforcement des programmes actuels et futurs et la ...réduction des grossesses non désirées au Sénégal.
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Les infections associées aux soins (IAS) touchent des centaines de millions de patients dans le monde chaque année. Ces infections sont à l’origine de pathologies graves, de prolongements de la durée du séjour en établissement de soins, d’invalidités à long terme, de coûts personnels im...portants pour les patients et leurs familles, de charges financières supplémentaires élevées pour les systèmes de santé, et pire encore, de la perte tragique de la vie.
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This 10th edition of the Institute for Health Metrics and Evaluation’s annual Financing Global Health report provides the most up-to-date estimates of development assistance for health, domestic spending on health, health spending on two key infectious diseases – malaria and HIV/AIDS – and fut...ure scenarios of health spending. Several transitions in global health financing inform this report: the influence of economic development on the composition of health spending; the emergence of other sources of development assistance funds and initiatives; and the increased availability of disease-specific funding data for the global health community. For funders and policymakers with sights on achieving 2030 global health goals, these estimates are of critical importance. They can be used for identifying funding gaps, evaluating the allocation of scarce resources, and comparing funding across time and countries.
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It describes and analyzes the theoretical-practical incidences of misinformation, disinformation, and malinformation, including but not limited to the Information Science framework. Besides, it aims to outline an understanding of these three concepts based on 16 arrangements intercon...nected according to their intentionality.
Conclusions: We highlight that the complexity that permeates the various fields in the present situation is due to the difficulty of reaching a consensus on the semantic definition of the concepts of information, misinformation, and its disambiguations since these concepts have various properties.
Also available in: Portuguese
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Chronic Non Communicable Diseases. Case Management Desk Guide
This helpdesk report seeks to establish what lessons have been learnt from the current and previous Ebola outbreaks. It recommends good practice and makes suggestions based on the evidence for good practice and preparedness to reduce transmission and prevent further risk and exposure in affected cou...ntries.
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Le résumé d’orientation du Rapport de situation de l’OMS sur la santé bucco-dentaire dans le monde passe en revue les données les plus récentes sur les principales maladies bucco-dentaires, les facteurs de risque, ainsi que les défis à relever et les possibilités de réforme du système ...de santé. Le rapport établit comme constat clair que la situation de la santé bucco-dentaire dans le monde est alarmante et nécessite une action urgente. Le rapport servira de référence aux décideurs et permettra d’orienter un large éventail de parties prenantes dans différents secteurs en vue de guider les efforts de sensibilisation en faveur d’une meilleure définition des priorités en matière de santé bucco-dentaire dans les contextes mondiaux, régionaux et nationaux. En outre, le rapport fournit, par le biais d’une ressource en ligne distincte, les tout premiers profils de la santé bucco-dentaire des pays pour l’ensemble des 194 États Membres de l’OMS, donnant un aperçu unique des domaines et des marqueurs clés de la santé bucco-dentaire qui sont pertinents pour les décideurs.
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WHO-OHCHR launch new guidance to improve laws addressing human rights abuses in mental health care
Ahead of World Mental Health Day, the World Health Organization (WHO) and the Office of the High Commissioner on Human Rights (OHCHR) are jointly launching a new guidance, entitled "Mental health, h...uman rights and legislation: guidance and practice", to support countries to reform legislation in order to end human rights abuses and increase access to quality mental health care.
Human rights abuses and coercive practices in mental health care, supported by existing legislation and policies, are still far too common. Involuntary hospitalization and treatment, unsanitary living conditions and physical, psychological, and emotional abuse characterize many mental health services across the world.
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Module 2
Community Educators and Advocates
July 2017
Module 2: Community educators and advocates. Community educators and advocates are needed to increase awareness about PrEP in their communities. This module provides information on PrEP that should be considered in community-led activities ...that aim to increase knowledge about PrEP and generate demand and access.
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The Lancet Global Health Published:May 12, 2020DOI:https://doi.org/10.1016/S2214-109X(20)30229-1
December 2015
National guidelines for of Clubfoot
The report shows that where people and communities living with and affected by HIV are engaged in decision-making and HIV service delivery, new infections decline and more people living with HIV gain access to treatment. When people have the power to choose, to know, to thrive, to demand and to work... together, lives are saved, injustices are prevented and dignity is restored.
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