Moçambique foi o primeiro país fora da região do Sahel a expandir com sucesso a quimioprevenção sazonal da malária (QSM). Neste documento de aprendizagem, descrevemos as lições decorrentes da aplicação em larga escala da QSM em Moçambique.
The Malaria Consortium website provides comprehensive information about the organization’s work in preventing, controlling, and eventually eliminating malaria and other communicable diseases. It showcases the organization’s projects, research, publications, and policy work across Africa and Asia.... The site highlights areas such as disease surveillance, health system strengthening, seasonal malaria chemoprevention, and integrated community case management.
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MSD Manual Consumer Version
Malawi's Ministry of Health officially declared on August 16, 2023, that the cholera outbreak is no longer a national health emergency. Since the outbreak began in February 2022, the country recorded 58,982 cholera cases and 1,768 deaths. Through coordinated efforts by the government, development pa...rtners, and local communities, the outbreak has been contained in 26 out of 29 districts.
Only a few isolated cases remain in areas affected by Cyclone Freddy. The Minister of Health emphasized the importance of water, sanitation, and hygiene (WASH) initiatives to prevent future outbreaks. The World Health Organization (WHO) praised Malawi’s progress and pledged continued support to mitigate remaining risks.
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La vidéo "Choléra - Questions & Réponses" de l'Organisation Mondiale de la Santé (OMS) explique les aspects essentiels du choléra, une maladie diarrhéique aiguë causée par l'ingestion d'eau ou d'aliments contaminés par la bactérie Vibrio cholerae. Elle met en avant les principaux symptôme...s, notamment une diarrhée aqueuse sévère, des vomissements et une déshydratation rapide, pouvant être mortelle sans traitement adéquat. La transmission se fait principalement par l’eau insalubre et les mauvaises conditions sanitaires. Pour prévenir la maladie, il est essentiel d'avoir accès à de l'eau potable, d'améliorer l'hygiène et l'assainissement, et d'utiliser la vaccination dans les zones à haut risque. En cas d'infection, la réhydratation orale ou intraveineuse est le traitement principal, tandis que les antibiotiques sont parfois administrés dans les cas graves. La vidéo insiste sur l'importance d'une intervention rapide et de mesures préventives pour limiter la propagation du choléra et protéger les populations à risque.
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The video "Cholera - Questions & Answers" by the World Health Organization (WHO) explains the essential aspects of cholera, an acute diarrheal disease caused by ingesting water or food contaminated with the Vibrio cholerae bacterium. It highlights the main symptoms, including severe watery diarrhea,... vomiting, and rapid dehydration, which can be fatal without proper treatment. Transmission occurs primarily through unsafe water and poor sanitation conditions. To prevent the disease, it is crucial to have access to clean drinking water, improve hygiene and sanitation, and use vaccination in high-risk areas. In case of infection, oral or intravenous rehydration is the primary treatment, while antibiotics are sometimes administered in severe cases. The video emphasizes the importance of rapid intervention and preventive measures to limit the spread of cholera and protect at-risk populations.
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Esta publicación ha sido concebida como una herramienta para el Equipo de Salud que atiende a niños en los diferentes niveles de la atención ambulatoria. Procura ser una referencia ágil y práctica para la consulta diaria, que contemple los aspectos
relevantes a tener en cuenta durante los cont...roles de salud. Las publicaciones de referencia señaladas al final del documento permiten profundizar diversos temas no
desarrollados aquí, entre los cuales se cuentan
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The Lancet Group publishes the latest monkeypox-related content across epidemiology, treatments, and much more. Here you can explore monkeypox content published across all Lancet journals and content types. All of our monkeypox content is free to access.
THIS LEAFLET AIMS AT GUIDING YOU THROUGH THE VERY FIRST DAYS OF AN OUTBREAK
The document provides guidance on managing acute diarrhoea outbreaks, specifically cholera and shigellosis. It outlines steps for identifying outbreaks, differentiating between cholera and shigellosis, and treating patients based on the severity of dehydration. Recommendations include the use of ora...l rehydration solutions (ORS), antibiotics in severe cases, and strict hygiene practices to prevent transmission. The document also emphasizes community protection measures such as disinfection of water sources, isolation of cases, and proper food hygiene. It is a practical resource for health workers to quickly respond to diarrhoeal disease outbreaks.
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UNICEF reports that the Democratic Republic of the Congo (DRC) is experiencing its most severe cholera outbreak in six years, with over 31,000 suspected or confirmed cases and 230 deaths in the first seven months of 2023. The North Kivu province is particularly affected, recording more than 21,400 c...ases, including over 8,000 children under five—a sixfold increase compared to all of 2022. The surge is attributed to escalating conflict and displacement in eastern DRC, leading to overcrowded camps with inadequate water and sanitation facilities, creating conditions conducive to cholera transmission. UNICEF emphasizes the urgent need for improved access to clean water, sanitation, and healthcare to prevent further spread of the disease.
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The document provides guidance on managing acute diarrhoea outbreaks, specifically cholera and shigellosis. It outlines steps for identifying outbreaks, differentiating between cholera and shigellosis, and treating patients based on the severity of dehydration. Recommendations include the use of ora...l rehydration solutions (ORS), antibiotics in severe cases, and strict hygiene practices to prevent transmission. The document also emphasizes community protection measures such as disinfection of water sources, isolation of cases, and proper food hygiene. It is a practical resource for health workers to quickly respond to diarrhoeal disease outbreaks.
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The technical note by the Global Task Force on Cholera Control (GTFCC) discusses the use of Oral Cholera Vaccines (OCVs) for international workers and travelers in cholera-affected areas. It reviews the effectiveness of WHO-prequalified vaccines (Dukoral®, Shanchol™, and Euvichol®), emphasizing ...their role in preventing infection and reducing transmission risks.
The document highlights concerns about travelers contracting cholera in endemic regions and potentially spreading the disease upon returning home. While the overall risk is considered low, certain groups, such as humanitarian workers and travelers to high-risk areas like South Asia, face a higher exposure.
Recommendations include vaccination for emergency and relief workers who may come into direct contact with cholera patients or contaminated environments. However, routine vaccination for general travelers is not widely recommended. The note also calls for better surveillance and studies to assess the potential of vaccines in preventing international transmission.
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The Interim Guidance on Cholera Rapid Diagnostic Tests (RDTs) by the Global Task Force on Cholera Control (GTFCC) provides recommendations for using RDTs to detect cholera in areas with limited laboratory capacity. It highlights the advantages of RDTs, such as rapid detection (within 30 minutes), ea...se of use by non-laboratory personnel, and their role in early outbreak identification and surveillance. However, it emphasizes that RDTs should not replace culture or PCR testing, as they vary in sensitivity (58-100%) and specificity (60-100%). The document advises on proper test selection, storage, training, and integration into national surveillance systems to enhance cholera response efforts.
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Drawing on lessons from recent events, WHO launched ‘PRET - Preparedness and Resilience for Emerging Threats’ to support countries in updating their pandemic plans. Building on the current global momentum, PRET applies a “mode of transmission lens.”
The first PRET module focuses on preparin...g for respiratory pathogens. Future modules will focus on other pathogen groups such as arthropod-borne viruses.
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MSF often responds to outbreaks of cholera in the countries we work. But how do we set up our cholera treatment centres to ensure our patients get the best care possible - and that the disease doesn't spread? Learn more about the layout and activities of an MSF cholera treatment centre in this inter...active guide.
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The document provides essential guidelines for managing cholera outbreaks. It includes instructions for preparing oral rehydration solutions (ORS) using simple ingredients like sugar and salt to treat dehydration caused by cholera. The text also emphasizes the importance of access to clean water, sa...nitation, and hygiene to prevent the spread of the disease. It is part of the World Health Organization's effort to provide clear, actionable steps for controlling cholera in affected areas.
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Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P...lasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
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Front. Malar. 3:1336324. doi: 10.3389/fmala.2025.1336324
The article introduces Pf-HaploAtlas, a new online tool developed by MalariaGEN to track genetic mutations in the Plasmodium falciparum parasite—the most deadly malaria-causing species. This app allows researchers and public health professionals to explore global data on drug resistance mutations ...and genetic variation across thousands of parasite genomes. The tool is designed to improve understanding of how malaria parasites evolve and spread, and to support efforts in monitoring antimalarial drug resistance. With an intuitive interface, Pf-HaploAtlas enables users to visualize haplotype patterns, compare regional differences, and access up-to-date data that can inform control strategies and research.
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