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Integrated Outbreak Analytics (IOA) applies a multidisciplinary approach to understanding outbreak dynamics and to inform outbreak response. It aims to drive comprehensive, accountable, and effective public health and clinical strategies by enabling communities, and national and subnational health a
...
uthorities to use data for operational decision-making. IOA embraces a holistic perspective of outbreak dynamics throughout: from the trigger questions to the data that are collected or accessed, to the interpretation of results and the recommendations that follow. In addition, IOA promotes co-development and monitoring of evidence informed actions.
The IOA toolkit aims to provide a clear understanding of IOA and highlight the importance of using an integrated, holistic approach to manage outbreak responses. It provides step-by-step guidance for setting up IOA and putting IOA principles into action. Finally, this toolkit provides guidance on applying IOA in humanitarian and emergency contexts, offering a practical and adaptable approach to informing public health emergency responses.
Developed based on the model from the Democratic Republic of the Congo (DRC), its creation involved extensive consultation with experts experienced in IOA applications. The toolkit was piloted in Tanganyika Province, DRC, as well as Somalia and Sudan, demonstrating its adaptability to diverse emergency scenarios. It builds upon an existing array of tools, templates, reports, case studies, animations, and publications used by stakeholders in diverse contexts.
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Early warning systems are an essential tool for risk management and disaster preparedness that help save lives and minimize the potential impact of disasters. To be effective, early warning systems need to rely on the direct participation of at-risk communities, facilitate public education and aware
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ness of risks, disseminate messages and warnings efficiently, and help maintain a constant state of preparedness to enable early action.
Accessed August 2025
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The overall objective of this approach is to accelerate efforts toward malaria elimination by increasing
access to early diagnosis and treatment. The specific objectives are to: Minimize the barriers that the population faces in accessing timely, quality diagnosis and treatment. Reduce the time bet
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ween diagnosis and the start of treatment. Reduce the parasite reservoir in symptomatic infected persons through early treatment. Maximize the transmission-blocking strategy by taking early action on gametocytes. Decrease the incidence of P. vivax relapses.Ultimately, disrupt malaria transmission and prevent mortalit.
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This publication provides an overview of evidence and guidance on the growing challenge of workplace heat stress in the context of climate change. It highlights the health and productivity risks faced by billions of workers, especially in manual labor sectors. The report details the physiological, s
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ocioeconomic, and mental health impacts of heat stress and outlines evidence-based strategies for prevention and mitigation. It emphasizes the need for occupational heat action programmes, stakeholder collaboration, and tailored interventions to protect vulnerable workers, reduce productivity losses, and support sustainable development in a warming world.
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Antimalarial chemotherapy is crucial for reducing morbidity, mortality, and drug resistance, and is the cornerstone of malaria control. Existing antimalarial drugs act at different stages of the parasite’s life cycle. These drugs range from classic agents such as chloroquine and quinine to newer a
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rtemisinin derivatives. They include tissue schizonticides, blood schizonticides, gametocytocides, and sporontocides. Artemisinin and its derivatives are the most effective and fastest-acting treatment against drug-resistant Plasmodium falciparum, achieving rapid parasite clearance and reducing transmission potential. Other key drugs include mefloquine, halofantrine, proguanil, sulfadoxine–pyrimethamine, atovaquone–proguanil, tetracyclines, clindamycin and azithromycin. Each of these drugs has a specific mechanism of action, pharmacokinetics, efficacy, safety profile and contraindications. Rational drug combinations and adherence to national treatment guidelines are essential for managing resistance, ensuring safety in vulnerable populations such as children and pregnant women, and optimising therapeutic outcomes in cases of both uncomplicated and severe malaria.
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The 2024 World Malaria Report shows that the malaria burden remains overwhelmingly concentrated in Africa. The continent accounted for 94% of global cases and 95% of malaria-related deaths in 2023. Although the number of malaria cases increased globally from 204 million in 2000 to 246 million in 202
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3, the number of deaths declined from 805,000 to 569,000. Children under five are still the most affected group, accounting for 76% of malaria deaths in Africa. A few countries, particularly Nigeria and the Democratic Republic of the Congo, carry the highest burden. Since 2000, Africa has significantly reduced malaria incidence and mortality, averting over 1.7 billion cases and 12 million deaths. Nevertheless, malaria continues to pose a significant health challenge, necessitating ongoing action and investment.
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Drawing on the World Health Organization’s package of NCD best buys, the report demonstrates how these evidence-based measures can help countries reduce premature deaths, strengthen health systems, and advance progress towards the Sustainable Development Goals. It provides policymakers, donors, ad
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vocates, and partners with a clear economic and social rationale for scaling up implementation of proven solutions. By framing NCD prevention and control as both a health and development priority, the report offers a roadmap for action that delivers benefits across populations, economies, and generations. The evidence is clear: investing in WHO’s best buys is not only possible—it is imperative. The time to act is now.
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Promoting and protecting the mental health and psychosocial wellbeing of children, adolescents, and their caregivers remains undamental to achieving the Sustainable Development Goals (SDGs), with a direct contribution to SDG 3 (Good Health and Well- eing). In 2024, UNICEF accelerated the scale-up o
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f integrated, multisectoral MHPSS programming. These efforts contributed to the strengthening of national and subnational child and adolescent mental health systems by supporting programming across the continuum of care, investing in workforce development, advancing data systems and evidence generation, and promoting institutional leadership and coordination mechanisms. UNICEF’s growing reach, particularly through health, education, and child protection systems, reflects a strategic commitment to embedding MHPSS in sustainable development frameworks and in responses that bridge humanitarian action and development programming.
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The health impacts of climate change are no longer a distant threat. They are being felt here and now and becoming more extreme.
To address these threats, the WHO Asia-Pacific Centre for Environment and Health in the Western Pacific Region (ACE) was established in 2019 through a partnership with
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the Seoul Metropolitan Government, the Ministry of Climate, Energy and Environment of the Republic of Korea and the World Health Organization (WHO).
The Centre’s mission is to strengthen cooperation and drive action where environment and health meet. This focus on environmental health has created a strong foundation for system-wide change.
This strategic plan builds directly on that work. Over the next five years, the Centre will expand its reach, supporting countries to take practical, systems-based action that ensures healthier people, healthier environments and a healthier planet.
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This plan, approved by the Organization’s 62nd Directing Council, was shaped by extensive consultations with countries and stakeholders, and commits to transformative health outcomes over the next six years, tackling noncommunicable diseases (NCDs), mental health, health security, fragmented healt
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h systems and services, and the elimination of communicable diseases, amongst others.
“The COVID-19 pandemic taught us that the Region of the Americas is stronger when we work together,” said Dr. Jarbas Barbosa, PAHO Director. “This Strategic Plan harnesses our collective strength to build resilient health systems, reduce disease burden, and improve health and well-being for all across the Americas.”
The plan builds on lessons from the COVID-19 pandemic, which exposed gaps in health systems while highlighting the power of joint action. It targets measurable impacts in countries, such as reducing maternal mortality, reversing rising suicide rates, and eliminating diseases like leprosy and Chagas.
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AIDS 2024, 38:1579–1588. Treatment interruptions are a barrier to successful antiretroviral therapy (ART). 'Fresh start messages', which leverage significant days on the calendar (e.g., new year, public holiday) in order to prompt action, have the
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potential to encourage people with HIV (PWH) to return to care. We evaluated a 'fresh start' intervention (text messages) to increase return to care in PWH who had missed their last appointment.
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EWARS is a surveillance system developed by the World Health Organization to detect and respond quickly to disease outbreaks in emergency settings where normal health systems are disrupted. It allows health facilities to report priority diseases on a regular basis and generates alerts when unusual p
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atterns or suspected outbreaks occur. The system is designed to be simple and fast to set up, even in remote areas, and supports rapid public health action to prevent the spread of disease during crises.
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The window to 2030, the SDG target year, is closing. Without accelerated and sustained progress, hard-won UHC gains risk being lost. Using revised and improved UHC indicators the report presents the latest available UHC data and concludes with a call to shared
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action.
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The document “Communicable Disease Surveillance and Response Systems: A Guide to Planning” is a World Health Organization (WHO) guide designed to help countries develop and strengthen national surveillance and response systems for communicable diseases . It explains why surveillance is essential
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for early detection of outbreaks, informed decision-making, and effective public health action, especially in the context of the revised International Health Regulations (2005).
The guide provides a structured approach to strategic and operational planning. It outlines how countries should assess their existing systems, define a vision and goals, identify expected key result areas (EKRAs), prioritize activities, set realistic targets, allocate resources, and monitor progress. It also includes practical tools such as templates, worksheets, and examples to support ministries of health in organizing planning workshops and developing multi-year strategic plans and annual operational plans. Overall, the document serves as a practical framework to improve preparedness, early warning, and response to public health emergencies.
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Monitoring air quality (for example collecting continuous and quality data) is integral and critical to detecting air pollutants and to ensuring information sharing with the public, policy-makers, and regulatory compliance. Air quality monitoring is also one of the first and necessary steps for quan
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tifying the health impacts from air pollution and monitoring progress towards reducing air pollution. The main pollutants (e.g. particulate matter [PM], nitrogen dioxide, and tropospheric ozone) should be monitored continuously and consistently. Sharing these high-quality and standardized data publicly is essential to raise awareness and encourage decision-makers to take action.
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BMC Public Health (2025) 25:3774 https://doi.org/10.1186/s12889-025-24555-6. The study results provide useful insights on how climate change influences malaria in African countries, and reiterates the need for a greater engagement of policymakers and social partners, in intensifying the
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action needed to fight the transmission of malaria in Sub-Sahara Africa
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The book is designed for use everywhere, and especially in low-resource settings. With its focus on improving conditions at the community level, this book proposes ways to challenge stigma and build support for people with epilepsy, especially in places where care is limited. Prevent, manage, live w
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ell with epilepsy, and take action against epilepsy stigma with this friendly and illustrated guide. This comprehensive, easily understood resource gives you a handle on complex physical and social aspects of epilepsy.
Now available to purchase now through Hesperian’s online book store!
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All young people, including those with special needs and from the most vulnerable groups, have the right to quality health care services. Unfortunately, this right is not a reality, particularly in the case of sexual and reproductive health services. Many youth in need of sexual and reproductive hea
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lth care may either decline or be denied access to health services for a variety of reasons: Providers are often biased and do not feel comfortable serving youth who are sexually active; youth do not feel comfortable accessing existing services because they are not "youth-friendly" and may not meet their needs; and, often, community members do not feel that youth should have access to sexual and reproductive health services.
To address provider and site bias toward serving youth, EngenderHealth created a training curriculum intended to sensitize all staff at a health care facility on the provision of youth-friendly services. The curriculum was created as a result of the participatory work that we have been doing with youth in Nepal to address the needs of all levels of providers at different service-delivery settings. The curriculum has been field-tested and used in Nepal, Russia, Mongolia, and the United States.
Youth-Friendly Services allows staff to reflect upon and assess their own beliefs about adolescent sexuality while ensuring that those values and attitudes do not compromise the basic sexual and reproductive health rights to which youth are entitled. The curriculum also helps providers understand cross-cultural principles of adolescent development and health needs specific to youth. Once participant knowledge, attitudes, and skills are improved, sites conduct a self-assessment on the youth-friendliness of their services and create an action plan for specific improvements.
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Cardiovascular disease is a major cause of disability and premature death throughout the world, and contributes substantially to the escalating costs of health care. The underlying pathology is atherosclerosis, which develops over many years and is usually advanced by the time symptoms occur, genera
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lly in middle age. Acute coronary and cerebrovascular events frequently occur suddenly, and are often fatal before medical care can be given. Modification of risk factors has been shown to reduce mortality and morbidity in people with diagnosed or undiagnosed cardiovascular disease.
This publication provides guidance on reducing disability and premature deaths from coronary heart disease, cerebrovascular disease and peripheral vascular disease in people at high risk, who have not yet experienced a cardiovascular event. People with established cardiovascular disease are at very high risk of recurrent events and are not the subject of these guidelines. They have been addressed in previous WHO guidelines.
Several forms of therapy can prevent coronary, cerebral and peripheral vascular events. Decisions about whether to initiate specific preventive action, and with what degree of intensity, should be guided by estimation of the risk of any such vascular event. The risk prediction charts that accompany these guidelinesb allow treatment to be targeted accord-
ing to simple predictions of absolute cardiovascular risk.
Recommendations are made for management of major cardiovascular risk factors through changes in lifestyle and prophylactic drug therapies. The guidelines provide a framework for the development of national guidance on prevention of cardiovascular disease that takes into account the particular political, economic, social and medical circumstances.
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DHS Working Paper No. 136
A total of 1,222 children age 6-23 months were included in this analysis. Twenty percent of children were stunted and 43% were moderately anemic. Regarding IYCF practices, only 16% of children received a minimum acceptable diet, 25% received diverse food groups, 58% were ... fed with minimum meal frequency, 85% currently breastfed, and 59% consumed iron-rich foods. Breastfeeding reduced the odds of being stunted. By background characteristics, male sex, perceived small birth size, children of short stature, and children of working mother were significant predictors of stunting. Iron-rich food consumption was inversely associated with moderate anemia. Among covariates, male sex and maternal anemia were also significant predictors of moderate anemia among children age 6-23 months.
The study concluded that stunting and anemia among young children in Myanmar are major public health challenges that need urgent action. more
A total of 1,222 children age 6-23 months were included in this analysis. Twenty percent of children were stunted and 43% were moderately anemic. Regarding IYCF practices, only 16% of children received a minimum acceptable diet, 25% received diverse food groups, 58% were ... fed with minimum meal frequency, 85% currently breastfed, and 59% consumed iron-rich foods. Breastfeeding reduced the odds of being stunted. By background characteristics, male sex, perceived small birth size, children of short stature, and children of working mother were significant predictors of stunting. Iron-rich food consumption was inversely associated with moderate anemia. Among covariates, male sex and maternal anemia were also significant predictors of moderate anemia among children age 6-23 months.
The study concluded that stunting and anemia among young children in Myanmar are major public health challenges that need urgent action. more