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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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WHO list of priority medical devices for management of cardiovascular diseases and diabetes
recommended

World Health Organization WHO (2021) C_WHO
This publication was developed in response to the need for a reference list of priority medical devices required for management of noncommunicable diseases (NCDs), focusing on cardiovascular diseases and diabetes, especially for low- and middle-income countries to support universal health coverage a... more
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Recommended package of interventions for HIV, viral hepatis and STI prevention, diagnosis, treatment and care for people who inject drugs: policy brief

World Health Organisation (WHO) (2023) C_WHO
HIV, viral hepatitis and STI epidemics, particularly among people who inject drugs and other key populations, continue to be fuelled by laws and policies criminalizing sex work; drug use or possession; diverse forms of gender expression and sexuality; stigma and discrimination; gender discrimination... more
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Guidelines for surveillance of drug resistance in tuberculosis

World Health Organization (2021) C_WHO
6th edition
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Operational manual on indoor residual spraying: Control of vectors of malaria, Aedes-borne diseases, Chagas disease, leishmaniases and lymphatic filariasis
recommended

World Health Organization WHO (2024) C_WHO
Indoor residual spraying (IRS) involves applying residual insecticide to potential vector resting sites on the interior surfaces of human dwellings or other buildings. The main aim of IRS is to kill vectors before they are able to transmit pathogens to humans. When carried out correctly, IRS has his... more
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WHO guideline for the treatment of visceral leishmaniasis in HIV co-infected patients in East Africa and South-East Asia 

World Health Organzation WHO WHO Neglected Tropical Diseases Department (2022) C_WHO
The leishmaniases are a group of diseases caused by Leishmania spp., which occur in cutaneous, mucocutaneous and visceral forms. They are neglected tropical diseases (NTDs), which disproportionately affect marginalized populations who have limited access to health care. HIV co-infected patients with... more
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Quality criteria for the evaluation of climate-informed early warning systems for infectious diseases

World Health Organization WHO (2021) C_WHO
The frequency of infectious disease epidemics is increasing, and the role of the health sector in the management of epidemics is crucial in terms of response. In the context of infectious disease epidemics, the use of climate-informed early warning systems (EWS) has the potential to increase the eff... more
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WHO consolidated guidelines on tuberculosis: module 4: treatment and care

World Health Organization WHO (2025) C_WHO
The Global Programme on Tuberculosis & Lung Health of the World Health Organization (WHO/GTB) is now combining all current recommendations into one overall set of consolidated guidelines on TB. The guidelines contain recommendations pertaining to all areas related to the programmatic management of T... more
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Young people and COVID-19: Behavioural considerations for promoting safe behaviours

World Health Organization WHO (2021) C_WHO
In the context of the coronavirus disease (COVID-19) pandemic response, WHO identifies young people as a priority target audience with specific concerns, experiences and behaviours. This policy brief provides relevant insights from behavioural evidence and a set of behavioural considerations for tho... more
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Tackling malaria in countries hardest hit by the disease: ministerial conference report, Yaoundé, Cameroon, 6 March 2024

World Health Organisation (WHO) (2024) C_WHO
The Malaria Ministerial Conference, co-hosted by WHO and the Government of Cameroon on 6 March 2024, brought together more than 400 stakeholders, including Ministers of Health and senior representatives from the African countries hardest hit by malaria, global health leaders, scientists, civil socie... more
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Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children: a field guide

World Health Organization WHO (2023) C_WHO
2nd edition. This second edition builds on the experience of more than 10 years of SMC deployment, and reflects changes introduced in the WHO guidelines for malaria, 3 June 2022. The goal of this publication is to share these best practices to improve SMC implementation, coverage, and monitoring and... more
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Community deployment of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine: a field guide

World Health Organization WHO (2024) C_WHO
The document outlines essential steps and provides guidance to countries on the adoption and deployment of c-IPTp so that it is integrated into the existing health system. It draws upon best practices and lessons learned from pilot implementation experiences in eight African countries and targets st... more
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Technical consultation to assess evidence on community-based delivery of intermittent preventive treatment in pregnancy for malaria

World Health Organization WHO (2023) C_WHO
Report of a virtual meeting 21–23 June 2022
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Diagnostic tests for detecting risk of Plasmodium vivax relapse

World Health Organization WHO (2024) C_WHO
Relapsing malaria caused by Plasmodium vivax parasites poses a significant challenge to global malaria elimination efforts. About one third of the population remains at risk of contracting P. vivax malaria, and 85% of P. vivax infections stem from reactivated latent parasites, leading to chronic ana... more
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Extending the WHO scheme for external quality assessment of nucleic acid amplification testing for monitoring antimalarial drug resistance: meeting report, 14 July 2023

World Health Organization WHO (2025) C_WHO
WHO recommends artemisinin-based combination therapies for treating uncomplicated malaria, alongside studies to monitor treatment effectiveness. Given the threat of antimalarial resistance, including partial resistance in several African countries, molecular tools are vital for tracking resistance. ... more
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Regional stakeholder meeting on the response to antimalarial drug resistance in Africa

World Health Organization WHO (2024) C_WHO
Meeting report, Kampala, Uganda, 7–8 November 2023
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Surveillance template protocol for pfhrp2/pfhrp3 gene deletions

World Health Organization WHO (2024) C_WHO
2nd edition. The purpose of this document is to present updated standardized protocols that P. falciparum-endemic countries can use to determine the prevalence of parasites with pfhrp2/3 gene deletions causing negative HRP2 RDT results among symptomatic falciparum patients. The findings should be us... more
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Global research agenda on malaria vaccine introduction and implementation

World Health Organization WHO (2024) C_WHO
Technical Report
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Malaria vaccines

World Health Organization WHO (2022) C_WHO
Preferred product characteristics and clinical development considerations
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WHO guideline for the prequalification assessment of insecticide-treated nets

World Health Organisation WHO (2024) C_WHO
The purpose of the guideline is to provide information to stakeholders on the necessary requirements for a complete prequalification dossier for insecticide-treated nets (ITNs). Its aim is to establish the baseline for dossier requirements which are necessary to assess ITN products for the purposes ... more