Sangath is a non-governmental, not-for-profit organisation committed to improving health across the life span by empowering existing community resources to provide appropriate physical, psychological and social therapies. Its primary focus areas include child development, adolescent and youth health..., and adult health and chronic disease.
Started in 1996 by seven professionals in Goa, Sangath developed a vision to provide professional healthcare services for developmental disabilities and mental health problems. Today, it is one of the largest NGOs in the state, with more than 100 service providers, two centres in Goa, projects across India, collaborations with leading institutions in the world, and international recognition for its path-breaking research and intervention programmes in the community.
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Peripheral artery disease (PAD) is the most underdiagnosed, underestimated and undertreated of the atherosclerotic vascular diseases despite its poor prognosis. There may be racial or contextual differences in the Asia-Pacific region as to epidemiology, availability of diagnostic and therapeutic mod...alities, and even patient treatment response. The Asian Pacific Society of Atherosclerosis and Vascular Diseases (APSAVD) thus coordinated the development of an Asia-Pacific Consensus Statement (APCS) on the Management of PAD.
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Background
Low- and middle-income countries now experience the highest prevalence and mortality rates of cardiovascular disease.
Main text
While improving the availability and delivery of proven, effective therapies will no doubt mitigate this burden, we posit that studies evaluating cardiovasc...ular disease risk factors, management strategies and service delivery, in diverse settings and diverse populations, are equally critical to improving outcomes in low- and middle-income countries. Focusing on examples drawn from four cardiovascular diseases — coronary artery disease, stroke, diabetes and kidney disease — we argue that ethnicity, culture and context matter in determining the risk factors for disease as well as the comparative effectiveness of medications and other interventions, particularly diet and lifestyle interventions.
Conclusion
We believe that a host of cohort studies and randomized control trials currently being conducted or planned in low- and middle-income countries, focusing on previously understudied race/ethnic groups, have the potential to increase knowledge about the cause(s) and management of cardiovascular diseases across the world.
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Diskriminierungssensibler Umgang mit Patient*innen ermöglicht allen Menschen gesundheitliche Hilfe aufzusuchen. Im Gesundheitssystem gibt es Menschen, die weniger sichtbar sind als andere. Damit sich Ärzt*innen, Therapeut*innen, Pflegende und andere im Gesundheitssystem
Tätige stärker mit indiv...iduellen Bedürfnissen von Patient*innen auseinandersetzen, gibt dieser
Leitfaden Impulse.
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Research to develop point-of-care tests is in progress. Treatment of Buruli ulcer comprises 8 weeks of combined antibiotics (rifampicin and clarithromycin). Complementary therapies such as wound care, skin graft and prevention of disability are needed in some cases to ensure full recovery.
The targ...et set by the World Health Organization (WHO) for control of Buruli ulcer is for countries to achieve a rate of case confirmation by PCR of at least 70%. All endemic countries have at least one PCR facility to support confirmation of cases. However, most countries in the WHO African Region have not been able to reach the target, and the rate of case confirmation has been declining
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The 23rd meeting of the WHO Expert Committee on Selection and Use of Essential Medicines was coordinated from Geneva, Switzerland, and held virtually from 21 June to 2 July 2021. The Committee considered 88 applications proposing additions, changes and deletions of medicines, medicine classes and fo...rmulations on the Model Lists of Essential Medicines. The Committee evaluated the scientific evidence for comparative effectiveness, safety and cost-effectiveness of the medicines in question. The Committee also considered a review of the therapeutic alternatives for medicines on the Model Lists, and update to the AWaRe classification of antibiotics, and reviews and reports relevant to the selection and use of essential medicines.
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These guidelines are based on the 3rd Edition of the WHO Guidelines (Published 2015) World Health Organization’s Guidelines for the treatment of malaria. Additional literature surveys have been undertaken. Factors that were considered in the choice of therapeutic options included effectiveness, sa...fety, and impact on malaria transmission and on the emergence and spread of antimalarial drug resistance. On-going surveillance is critical given the spread of artemisinin resistance in Southeast Asia, although not yet confirmed anywhere in Africa. The guidelines on the treatment of malaria in South Africa aim to facilitate effective, appropriate and timeous treatment of malaria, thereby reducing the burden of this disease in our communities. This is essential to further reduce the malaria case fatality rates currently recorded in South Africa, to decrease malaria transmission and to limit resistance to antimalarial drugs.
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Interactive Graphic.This interactive graphic covering our current knowledge of the Ebola virus and the history of disease outbreaks has now been updated with information on convalescent therapies and on drug and vaccine developmen
This guide covers: Treatment That Works; Myths About Treatment; Success Stories; Resources | Do you or a loved one have PTSD? There is no need to suffer. Treatment works. If you have PTSD—posttraumatic stress disorder — you don’t have to suffer. There are good treatments that can help. This b...ooklet describes therapies and medications that are proven to help people with PTSD.
You’ll hear from experts about what treatment is like, and how it can help you. Don’t let PTSD get in the way of your enjoyment of life, hurt your relationships, or cause problems for you at
work or school. PTSD treatment works.
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The ACT Consortium was an international research collaboration dedicated to evaluating the effectiveness, safety and implementation of artemisinin-based combination therapies (ACTs) for treating malaria. Operating across multiple countries in Africa and Asia, the consortium conducted over 25 studies... focused on improving malaria case management, drug delivery, diagnostic practices and patient outcomes. Emphasising interdisciplinary research, the consortium generated robust evidence to inform national malaria control policies and global health strategies. This website serves as a comprehensive archive of the consortium's work, providing researchers, policymakers, and programme implementers in global health and infectious disease control with access to protocols, guidance documents, data tools, and peer-reviewed publications.
Accessed on 15/0//2025.
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DOI: 10.5772/intechopen.102891Little progress has been made since the 1960s and 19. 70s to widen the therapeutic arsenal against Trypanosoma cruzi, the causative pathogen of Chagas disease, which remains a frustrating and perplexing infectious disease. This chapter focuses on the strategic and opera...tional challenges in the clinical drug development of a novel antitrypanosomal agent for Chagas disease. The various elements that contribute to a robust assessment of treatment effect including dose selection, choice of patient population, trial methodology, endpoint measures, and regulatory perspectives are discussed. The learnings herein should serve as resource to help researchers and other stakeholders optimize their clinical development plans and speed delivery of new medicines to patients with Chagas disease.
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The updates are based on evidence emerging from the: Ongoing monitoring of the disease. Protection that the population already developed against COVID-19 through previous infection or vaccination. Epidemiological situation, availability of diagnostic tests and access to therapeutic options.
European Scientific Journal March 2015 edition vol.11, No.9 ISSN: 1857 – 7881 (Print) e - ISSN 1857- 7431
Objective: To describe the clinical, therapeutic and outcome aspects of emergency obstetric care at the University Hospital of Parakou in Benin
Existing data on chronic obstructive pulmonary disease (COPD) prevalence are irregularly distributed around the world, and in many geographic regions data are scarce or even nonexistent. This fact hinders the implementation of adequate preventive and therapeutic interventions to reduce the high burd...en and costs of COPD. In the current study, we have used the Geographic Information System (GIS) inverse distance weighted (IDW) interpolation technique with the objective of visualising spatial data of COPD prevalence in the world and obtaining a visual impression of the magnitude of this global health problem. GIS has been recognised as an effective tool to display the geographical distribution of data, even when they are few and widely separated, as is the case with the prevalence of COPD.
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The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public health problem throughout Latin America. Current therapeutic options are characterised by limited efficacy, long treatment regimens and frequent toxic side-effects. Advances in this area have been compromised by gaps... in our knowledge of disease pathogenesis, parasite biology and drug activity. Nevertheless, several factors have come together to create a more optimistic scenario. Drug-based research has become more systematic, with increased collaborations between the academic and commercial sectors, often within the framework of not-for-profit consortia. High-throughput screening of compound libraries is being widely applied, and new technical advances are helping to streamline the drug development pipeline. In addition, drug repurposing and optimisation of current treatment regimens, informed by laboratory research, are providing a basis for new clinical trials. Here, we will provide an overview of the current status of Chagas disease drug development, highlight those areas where progress can be expected, and describe how fundamental research is helping to underpin the process.
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In den letzten Jahren hat die öffentliche Debatte über Kinderschutzfragen zu entscheidenden Veränderungen - sowohl in der Öffentlichkeit wie in der Fachdebatte in Deutschland - geführt. Anfang 2012 trat ein neues Bundeskinderschutzgesetz in Kraft; der Aufarbeitungsprozess nach dem Missbrauchssk...andal, der Deutschland ab Anfang 2010 in einer breiteren öffentlichen Diskussion erschüttert hat, hat mit dem Abschluss der Arbeit der Unabhängigen Beauftragten zur Aufarbeitung des sexüllen Kindesmissbrauchs, der ehemaligen Bundesfamilienministerin Frau Dr. Christine Bergmann, und mit dem Abschlussbericht des Runden Tisches Ende 2011 eine Bestandsaufnahme abgeschlossen und eine Agenda für die weitere Arbeit der Umsetzung aufgestellt. Zu diesen zahlreichen zu bearbeitenden Punkten gehören auch ein hilfreicherer Umgang mit Betroffenen im Gesundheitswesen, eine bessere Diagnostik und Abklärung in Kinderschutzfällen, auch auf der medizinischen Seite. Verzögerungen bei der Implementation von Hilfe, Unterstützungsmaßnahmen und Therapien werden beklagt und Lotsenfunktionen in Bezug auf gesetzliche Ansprüche wie z.B. im Rahmen des Opferentschädigungsrechts werden vorgeschlagen.
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This document updates the ARIA sections on the links between rhinitis and asthma. Relevant publications between January 2000 and December 2005 were included. Complementary and alternative medicine is not evaluated in this document since it has been published separately. Likewise, an update on pharma...cological therapy of AR was published separately. Therefore, in the therapeutical component of the current review we decided to focus on aspects related to concomitant rhinitis and asthma.
The aim of this review was to present new evidence related to major ARIA statements, either to support or to refute them, by bringing the most recent information in the context of the previous knowledge on this subject. Additionally, we looked for information that could potentially lead to novel statements.
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Ein Bilderbuch über Hilfe nach traumatischen Erlebnissen für Eltern und Kinder mit Kriegs- und Fluchterfahrung .
Das Trauma-Bilderbuch versucht, ein schweres Thema verständlich darzustellen: Ein Kind erlebt kriegsbedingt eine überwältigende Angstsituation, der „Schatten dieser Angst“ verfo...lgt das Kind noch, wenn die schreckliche Situation bereits eine ferne Vergangenheit geworden sein könnte.
Es kann Kindern, Eltern und deren Unterstützern helfen, die ebenso unsichtbare wie lebenseinschränkende Belastung zu verstehen. Es zeigt auf, was das Kind jetzt braucht: praktische Hilfen im Alltag, tröstende Botschaften der Eltern und evt. den Weg in eine Therapie.
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Dans la plupart des pays, les services de lutte contre la tuberculose (TB) sont décentralisés jusqu’aux dispensaires
les plus périphériques et souvent au sein même des villages et des quartiers. Par contre, les services
de lutte contre le VIH/Sida sont généralement beaucoup plus centralis...és parce que la diffusion des
soins, notamment de la thérapie antirétrovirale (TARV), n’a commencé qu’assez récemment. De ce fait,
les patients qui ont besoin d’un traitement à la fois contre la tuberculose et le VIH/Sida peuvent être obligés
de se rendre dans deux établissements distincts et ainsi d’avoir à parcourir de longues distances pour
accéder aux soins. L’absence de services intégrés TB/VIH peut provoquer des retards dans le diagnostic
et le traitement, et même se traduire par un mauvais suivi des traitements, voire par des interruptions. Par
ailleurs, les patients ont à supporter la charge financière des frais de déplacement et des autres coûts indirects,
tels que de longs temps d’attente et une perte de revenu
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Guide pratique à l’usage des médecins, infirmiers, techniciens de laboratoire, auxiliaires de santé, techniciens sanitaires et logisticiens.
Le document est un guide complet pour la gestion des épidémies de choléra, fournissant des protocoles détaillés pour la prévention, l’investigat...ion des épidémies, le traitement et les mesures de contrôle. Il couvre des aspects essentiels tels que la thérapie de réhydratation, l’assainissement de l’eau, la promotion de l’hygiène et la mise en place de centres de traitement. Conçu pour le personnel médical et non médical, il vise à soutenir une réponse efficace aux épidémies et à réduire la morbidité et la mortalité liées au choléra.
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