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Serious adverse events following treatment of visceral leishmaniasis: A systematic review and meta-analysis

Singh-Phulgenda, S., Dahal, P., Ngu, R. et al. PLOS Neglected Tropical Diseases (2021) C1
Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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The Treatment of Diarrhoea

World Health Organization WHO (2005) C_WHO
A manual for physicians and other senior health workers. This fourth revision of the manual reflects recent clinical experience and research findings in diarrhoea case management. Compared to earlier versions, it includes revised guidelines on the management of children with acute diarrhoea using th... more
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Extreme heat: Preparing for the heatwaves of the future

The International Federation of Red Cross and Red Crescent Societies IFRC; OCHA; Red Cross Red Crescent Climate Centre (2022) C1
Climate change is already having severe impacts across our planet, bringing new and previously unimaginable challenges to the people least responsible for greenhouse gas emissions. This report, the first we’ve released jointly in the history of our organizations, provides a sobering review of h... more
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Global analysis of health care waste in the context of COVID-19

World Health Organization WHO (2022) CC
The COVID-19 pandemic has led to large increases in healthcare waste, straining under resourced healthcare facilities and exacerbating environmental impacts from solid waste. This report quantifies the additional COVID-19 healthcare waste generated, describes current healthcare waste management syst... more
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Direct and indirect effects of the COVID-19 pandemic and response in South Asia

UN Children's Fund UNICEF (2021) C_UNICEF
It estimates that there have been 228,000 additional deaths of children under five in these six countries [Afghanistan, Nepal, Bangladesh, India, Pakistan and Sri Lanka] due to crucial services, ranging from nutrition benefits to immunisation, being halted. It says the number of children being tr... more
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Covid-19 Pandemic: Impact of restriction measures in West Africa

World Food Program WFP (2020) CC
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Global consultation of National Leprosy Programme managers, partners and affected persons on Global Leprosy Strategy 2021–2030

World Health Organization WHO (2020) C_WHO
The World Health Organization organized a Consultation of National Leprosy Programme managers, partners and affected persons to discuss the draft Global Leprosy Strategy, 2021--2030. This virtual event took place from 26 to 30 October 2020. It was attended by more than 450 stakeholders. Contribution... more
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ESC Guidance for the Diagnosis and Management of CV Disease during the COVID-19 Pandemic

European Society of Cardiology (2020) C1
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV‑2) causing coronavirus disease 2019 (COVID-19) has reached pandemic levels; Patients with cardiovascular (CV) risk factors and established cardiovascular disease (CVD) represent a vulnerable population when suffering from COVID-19; Patien... more
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Understanding the Impact of COVID-19

Assessment Capacities Project ACAPS (2020) C2
This report provides an overview of the key information gaps and limitations in interpreting existing COVID-19 data
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Guidance Note: Protection of Children during Infectious Disease Outbreaks

Arii M., F. Baele, J. Bedford et al. The Alliance for children protection in humanitarian action (2020) C2
Accessed on 31.03.2020 This Guidance Note aims to provide humanitarian child protection practitioners, particularly child protection advisors and program managers, with guidance on how to engage in responses to infectious disease outbreaks to ensure children’s protection needs are taken into ac... more
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National Guidelines for the Management of Viral Hepatitis

Spearman, CWN; MW Sonderup, Y Pillay et al. National Department of Health South Africa (2020) CC
Viral hepatitis is defined as inflammation of the liver cells due to viral infection. The burden of liver disease in South Africa is mostly underestimated as viral hepatitis, in particular chronic infection, is a silent and neglected cause of morbidity and mortality. However, the burden of disease i... more
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The Power of Cities: Tackling Noncommunicable Diseases and Road Traffic Injuries

World Health Organization WHO (2019) C_WHO
The report is geared towards mayors, local government officials and city policy planners.It highlights key areas where city leaders can tackle the drivers of NCDs, including tobacco use, air pollution, poor diets and lack of exercise, and improve road safety. From anti-tobacco actions in Beijing a... more
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Contraceptive eligibility for women at high risk of HIV

World Health Organization (2019) C_WHO
Guidance statement Recommendations on contraceptive methods used by women at high risk of HIV
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2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline
recommended

World Health Organization WHO (2019) C_WHO
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions. Gr... more
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The Core Elements of Human Antibiotic Stewardship Programs in Resource-Limited Settings: National and Hospital Levels
recommended

Centers for Disease Control and Prevention CDC (2018) C_CDC
Formularies are lists of antibiotics that are suggested for certain healthcare settings. In developing a recommended formulary, countries should consider the needs of patients and facilities where they receive care. For example, clinicians in rural or primary health centers may need wide access to f... more
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Guidelines for the vaccination of HIV-infected adolescents and adults in South Africa

S. K. Dlamini; S. A. Madhi; R. Muloiwa; et al. Southern African Journal of HIV Medicine; AOSIS (2018) CC
Southern African Journal of HIV Medicine ISSN: (Online) 2078-6751, (Print) 1608-9693 http://www.sajhivmed.org.za Published: 23 May 2018
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Bending the Curve - Keeping our Promise of Ending TB in the South-East Asia Region on time

World Health Organization. Regional Office for South-East Asia (2018) C_WHO
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Mental health in the Americas: an overview of the treatment gap

Kohn R, Ali A, Puac-Polanco V, Figueroa C, López-Soto V, Morgan K, et al. Rev Panam Salud Publica (2018) CC
To understand the mental health treatment gap in the Region of the Americas by examining the prevalence of mental health disorders, use of mental health services, and the global burden of disease.
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The Core Elements of Human Antibiotic Stewardship Programs in Resource-Limited Settings

Centers for Disease Control and Prevention CDC (2018) C_CDC
Antibiotic stewardship refers to coordinated efforts and activities that seek to measure and improve use of antibiotics. Implementation of ASPs has demonstrated positive public health and clinical impacts including reducing costs, lengths of hospital stays, and the burden of antibiotic resistance wh... more