Guidelines for the treatment of human African trypanosomiasis. Web Annex A. Commissioned by WHO Cochrane Response
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions.
Gr...am-negative bacteria, such as Klebsiella pneumoniae and Escherichia coli, can cause severe and often deadly infections that pose a particular threat for people with weak or not yet fully developed immune systems, including newborns, ageing populations, people undergoing surgery and cancer treatment.
The report highlights a worrying gap in activity against the highly resistant NDM-1 (New Delhi metallo-beta-lactamase 1), with only three antibiotics in the pipeline. NDM-1 makes bacteria resistant to a broad range of antibiotics, including those from the carbapenem family, which today are the last line of defence against antibiotic-resistant bacterial infections.
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The use of Delamanid and Bedaquiline for Children with Drug-Resistant Tuberculosis.
Standard for the Exchange of Earthquake Data
In this guide, the African Palliative Care Association (APCA) has put together evidence‑based information on the use of specific opioids commonly used in the management of moderate‑to‑severe pain to manage both cancer and non‑cancer pain. APCA hopes that this guide will be a useful tool i...n aiding health professionals at all levels of healthcare delivery to assess and manage pain using opioids. All opioids included in this guide are listed on the WHO model list of essential medicines but we remind readers that oral morphine is the standard opioid of choice for managing moderate‑to‑severe pain and we recommend that it should be made available at all times.
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Understanding and addressing violence against women
Anxiety Disorders
Chapter F.4
PLoS Negl Trop Dis 16(10): e0009774. Although the practice of communication is often called upon when intervening asn involgvingcommunties affected by NTD's, the disciplinary framewokr of healt communication research has been largely absent from NTD strategies. To illustrate how practices conceptual...ized and developed within the communication field habe been applied in the context of NTD elimination, we conducted a scoping review focusing on two diseases currently targeted for elimination by the WHO: lymphatic filariasis and Chagas disease
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Practical Guidelines of Insulin Therapy in Diabetes Mellitus Patients
The Government of India is embarking on a mammoth task to prevent COVID-19 spread among communities. The Rapid Evidence Synthesis team received a request to support the planning and development of resources for ensuring preparedness of FLHWs for COVID-19 . The rapid evidence synthesis was conducted ...in a period of three days.
The findings highlight what we can learn from recent pandemics such that we are prepared for potential scenarios and challenges due to COVID-19. Key issues which decision-makers need to consider, based on available evidence
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En s’appuyant sur les ODD et sur la Stratégie mondiale, ainsi que sur la Convention relative aux droits de l’enfant (CRC) et sur la Convention sur l’élimination de toutes les formes de discrimination à l’égard des femmes (CEDAW ), l’UNICEF imagine un monde où aucun enfant ne décède ...de maladies évitables, et où chacun d’entre eux réalise pleinement son potentiel sur le plan de la santé et du bien-être. Pour les cinq premières années (2016-20), la Stratégie de l’UNICEF en matière de santé (ci-après dénommée «la Stratégie») fixe deux grands objectifs :
1. Mettre fin aux décès évitables de mères, de nouveau-nés et d’enfants;
2. Promouvoir la santé et le développement de tous les enfants.
Pour atteindre ces objectifs, la Stratégie prend en considération les besoins des enfants en matière de santé à tous les stades de la vie.
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Dialogues Clin Neurosci. 2017 Jun; 19(2): 93–107.