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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Communicable disease threats report, 11 November 2017

European Centre for Disease Prevention and Control (2017) C1

The ECDC Communicable Disease Threats Report (CDTR) is a weekly bulletin for epidemiologists and health professionals on active public health threats. This issue covers the period 5-11 November 2017 and includes updates on measles, rubella, chikungunya, West Nile virus, Plague, monkeypox, legionnair... more

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Monkeypox: Current status in West and Central Africa

World Health Organization (WHO) (2018) C_WHO

Monkeypox is an emerging viral zoonosis with symptoms similar to those observed in smallpox patients, although less severe. Since the global eradication of smallpox in 1980, monkeypox has emerged as the most important orthopoxvirus in humans. The Advisory Committee on Variola Virus Research (ACVVR) ... more

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The impact of Covid-19 on HIV, TB and Malaria Services and Systems for Health: a Snapshot from 502 health facilities across Africa and Asia

The Global Fund (2021) CC

In 2020, the COVID-19 pandemic impacted the world beyond imagination. To date, it has infected more than 135 million people, killed over 2.9 million people, and is projected to plunge up to 115 million people into extreme poverty.1 As countries have gone into lockdown, gender-based violence has incr... more

Manual de Vigilância do Óbito no Contexto da Síndrome Inflamatória Multissistêmica Pediátrica Associada à Covid-19

Ministério da Saúde, Brasil (2021) C2

O Ministério da Saúde (MS), por meio da Coordenação-Geral do Programa Nacional de Imunizações (CGPNI) e da Coordenação-Geral de Informações e Análises Epidemiológicas (CGIAE) da Secretaria de Vigilância em Saúde (SVS) publica o Protocolo de Vigilância do Óbito no Contexto da síndrom... more

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Recomendaciones psicológicas para explicar a la infancia el brote de Coronavirus-COVID19

Colegio Oficial de Psicología de Madrid (2020) C1

RECOMENDACIONES PSICOLÓGICAS PARA EXPLICAR A NIÑOS Y NIÑAS EL BROTE DE CORONAVIRUS-COVID 19 El Colegio Oficial de la Psicología de Madrid, a través de la Sección de Psicología Clínica, de la Salud y Psicoterapia, quiere transmitir una serie de pautas dirigidas a padres, profesionales y fami... more

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Apercu des Besoins humanitaires 2016

l’Equipe Humanitaire Pays (2015) C2

le Sénégal continue d’être confronté à une crise alimentaire et nutritionnelle qui touche particulièrement le nord et l’est du pays. Selon les estimations faites en novembre 20151, plus de 2,4 millions de personnes sont en insécurité alimentaire (soit 17% de la population), dont 220 461 ... more

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Disability considerations for COVID-19 vaccination

World Health Organization WHO; UNICEF (2021) C_WHO

Available in Chinese, English, French, Russian and Spanish; WHO and UNICEF policy brief, 19 April 2021 Persons with disabilities are disproportionately impacted by COVID-19, both directly because of infection, and indirectly because of restrictions to reduce the spread of the virus. Persons with di... more

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Scoping review of interventions to maintain essential services for maternal, newborn, child and adolescent health and older people during disruptive events

World Health Organization WHO (2021) C_WHO

To support countries in adapting their response to different COVID-19 scenarios, the World Health Organization (WHO) Department of Maternal, Newborn, Child and Adolescent Health and Ageing commissioned this scoping review of published and grey literature. The objective was to identify interventions ... more

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Directrices provisionales de bioseguridad de laboratorio para el manejo y transporte de muestras asociadas al nuevo coronavirus 2019 (2019-nCoV)

OPS OPS (2020) C_WHO

En enero de 2020, el agente etiológico responsable de un grupo de casos de neumonía grave en Wuhan, China, fue identificado como un nuevo betacoronavirus (2019-nCoV), distinto del SARS-CoV y MERS-CoV (1) (2) (3). La secuencia genómica completa de este nuevo agente está disponible y se han desarr... more

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Manual for the care and management of patients in Ebola Care Units/ Community Care Centres - Interim emergency guidance, January 2015
recommended

World Health Organization (2015)

This manual provides guidance on best practices to be followed in Ebola Care Units (ECUs)/Community Care Centres (CCCs). It is intended for health aid workers (including junior nurses and community health-care workers) and others providing care for patients in ECUs/CCCs. While the focus is on the ca... more

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Information note on HIV and COVID-19

World Health Organization WHO (2020) C_WHO

People living with HIV depend on life-saving antiretroviral therapy (ART) and access to ART must be maintained during periods of travel restrictions and lockdowns resulting from the COVID-19 pandemic. The Information note on HIV and COVID-19 addresses common concerns people living with HIV have rega... more

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Sick Development

Anna Marriott Oxfam International (2023) CC

Development finance institutions owned by European governments and the World Bank Group are spending hundreds of millions of dollars on expensive for-profit hospitals in the Global South that block patients from getting care, or bankrupt them, with some even imprisoning patients who cannot afford th... more

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Beware long-term damage to human rights and refugee rights from the coronavirus pandemic: UNHCR

UNHCR (2020) CC

The coronavirus pandemic has deepened the plight of people fleeing war, conflict and persecution. As countries battle to protect their populations and economies, fundamental norms of refugee and human rights law are at risk. “The core principles of refugee protection are being put to test – b... more

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COVID-19 vaccine side effects (Video)

World Health Organization WHO (2021) C_WHO

Vaccines are designed to give you immunity without the dangers of getting the disease. It’s common to experience some mild to moderate side effects when receiving vaccinations. This is because your immune system instructs your body to increase blood flow so more immune cells can circulate, and it ... more

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Recomendações importantes sobre água, saneamento e higiene COVID - 19 na comunidade

Organização Pan-American da Saúde OPS (2020) C_WHO

RECOMENDAÇÕES IMPORTANTES SOBRE ÁGUA, SANEAMENTO (esgoto ) E HIGIENE COVID - 19 NA COMUNIDADE2 Boas práticas com água, saneamento e higiene, em particular lavagem de mãos com sabão e água limpa, devem ser estritamente aplicadas e mantidas, pois são importantes barreiras adicionais para ... more

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Patterns of funding allocation for tuberculosis control in fragile states

Warsame A.; Patel P.; Checchi F. International Journal of Tubercolosis and Lung Disease (2014) CC

The Creditor Reporting System was analysed for official development assistance funding disbursements towards TB control in 11 conflict-affectedstates, 17 non-conflict-affected fragile states and 38 comparable non-fragile states. The amounts of funding, funding relative to burden, funding relative to... more

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O álcool e a COVID-19: o que você precisa saber

Pan American Health Organization PAHO, World Health Organization WHO (2020) C_WHO

Este folheto informativo contém informações importantes que você deve saber sobre o consumo de álcool e a COVID-19. Aborda, entre outras coisas, a desinformação que está sendo difundida por meio das redes sociais e outros meios de comunicação sobre o álcool e a COVID-19. O mais important... more

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Coronavirus COVID-19 Isolement à domicile

Ministère de la Santé - Le Gouvernement Luxembourgeis (2020) C1

Vous avez une infection confirmée mais vous ne devez pas être hospitalisé car votre état général est bon. Vous devez néanmoins être isolé à domicile. Les personnes vivant sous le même toit et vos relations intimes doivent se mettre en auto-quarantaine pour une période de 7 jours. Ces rec... more

Manual for the care and management of patients in Ebola Care Units/ Community Care Centres - Interim emergency guidance, January 2015 recommended

Manual for the care and management of patients in Ebola Care Units/ Community Care Centres - Interim emergency guidance, January 2015
recommended