This study, conducted by Tudu et al. (2020), explores the clinical characteristics and outcomes of patients with concurrent malaria and HIV infection, a combination that is relatively understudied in India. The research was carried out at the Department of Medicine, VIMSAR, Odisha, over a one-year p...eriod and included patients who presented with fever lasting up to seven days. Out of 340 patients diagnosed with malaria, 52 (15.29%) were found to also be HIV-positive.
The patients were divided into three groups: Group A with malaria and HIV co-infection, Group B with HIV mono-infection, and Group C with malaria mono-infection. The clinical presentation in co-infected patients resembled that of HIV more closely than malaria. Common symptoms in the co-infected group included fever (82.7%), vomiting (72.3%), anemia (72.3%), headache (65.4%), and aspiration pneumonia (57.7%). Laboratory findings revealed that a significant number of co-infected patients had hemoglobin levels below 7 g/dL and CD4 cell counts under 200 cells/μL, indicating advanced immunosuppression.
All patients received antimalarial treatment with injectable artesunate and antiretroviral therapy (ART). Despite appropriate treatment, the outcome for co-infected patients was comparatively worse: while 48 out of 52 recovered, 6 patients died, mainly due to complications such as anemia, acute kidney injury, and aspiration pneumonia.
In conclusion, the study highlights that although malaria-HIV co-infection is not highly prevalent, it is associated with severe clinical outcomes. Routine screening for both infections in febrile patients is recommended to ensure timely diagnosis and treatment.
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Presentation Current WHO guidance, strategies and lessons learnt of pre- and post-validation surveillance of NTDs
Le monde fait face aux conséquences graves du manque de services et de traitements de santé mentale disponibles. Les troubles mentaux touchent tous les pays, toutes les cultures et toutes les collectivités. Selon l’Organisation mondiale de la Santé (OMS), 10% de la charge mondiale de morbidit... est liée aux troubles mentaux, neurologiques et à l’usage de substances psychoactives.
Dans les pays à revenu faible ou intermédiaire, plus de 75% des personnes atteintes de troubles mentaux ne reçoivent aucun traitement. En 2020, en raison de la pandémie mondiale, 93% des pays ont déclaré que leurs services de santé mentale ont été suspendus ou interrompus (OMS, 2020e). L’OMS a signalé une hausse de 25% des cas de dépression et d’anxiété durant la pandémie. L’Organisation de coopération et de développement économiques (OCDE) estime que la dépression et l’anxiété coûtent à l’économie mondiale 1 000 milliards d’USD par an.
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En este documento se ofrece, en un formato de fácil consulta, el panorama general de las cuestiones relativas a la salud y los derechos sexuales y reproductivos que pueden afectar a los derechos humanos, la salud y el bienestar de los adolescentes (de edades comprendidas entre los 10 y los 19 años...) y las directrices pertinentes de la Organización Mundial de la Salud (OMS) para abordar dichas cuestiones. Este documento permite acceder al amplio conjunto de directrices de la OMS al respecto y constituye un útil recurso para la labor de promoción, formulación de políticas, investigación y diseño de programas y proyectos. Tiene por finalidad apoyar la aplicación de la Estrategia Mundial para la Salud de la Mujer, el Niño y el Adolescente 2016-2030 (1) y está armonizado con las medidas mundiales aceleradas en favor de la salud de los adolescentes (AA HA!) de la OMS y el marco operativo de la OMS sobre salud sexual y su relación con la salud reproductiva (2, 3).
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D’un format facilement accessible, simple à utiliser, le présent document décrit succinctement
les problèmes liés à la santé et aux droits en matière de sexualité et de reproduction qui peuvent
affecter les droits fondamentaux, la santé et le bien-être des adolescents (âgés de 10 à... 19 ans)
et il présente les lignes directrices pertinentes de l’Organisation mondiale de la Santé (OMS). Ce
document donne accès aux nombreuses lignes directrices formulées par l’OMS, et il constitue
une source d’informations utile pour les activités de sensibilisation, la conception des politiques
et des programmes ou projets et la recherche. Son objectif est de soutenir la mise en oeuvre
de la stratégie mondiale pour la santé des femmes, des enfants et des adolescents 2016–2030 (1), en conformité avec le cadre pour une action mondiale accélérée en faveur de la santé des
adolescents et avec le cadre opérationnel de l’OMS sur la santé sexuelle et ses liens avec la
santé reproductive (2,3).
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Este documento muestra las acciones que son requeridas para la prevención, control, vigilancia y coordinación multisectorial para una adecuada y efectiva acción frente al riesgo sanitario que implica la introducción del CHIKV en nuestro país
La mortalité maternelle et néonatale demeure un problème de santé publique au Bénin. Tous les efforts déployés par l’Etat béninois et les Partenaires Techniques et Financiers ont abouti à peu d’amélioration de la santé des mères et des nouveau-nés. Les Objectifs du Millénaire pour ...le Développement (OMD) n°4 et 5 en rapport avec la santé maternelle et infantile n’ont pas été atteints en 2015 comme programmé.
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MEDBOX Issue Brief no. 7, Dec. 2020
Die Impfung gegen die Ausbreitung des SARS-CoV-2-Virus stellt einen Meilenstein in der Bekämpfung der Pandemie dar. Für den Erfolg der Impfung unabdingbar ist eine gute Kommunikation und Aufklärung der Bevölkerung. Im Folgenden sind einige Informationen zur I...mpfstrategie, Durchführung der Impfung, ethische Überlegungen, sowie Aufklärungsmaterialien in deutscher und englischer Sprache aufgelistet
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This study aimed to analyze the geographical distribution of coronavirus disease 2019 (COVID-19) and to identify high-risk areas in space and time for the occurrence of cases and deaths in the indigenous population of Brazil. This is an ecological study carried out between 24 March and 26 October 20...20 whose units of analysis were the Special Indigenous Sanitary Districts. The Getis-Ord General G and Getis-Ord Gi* techniques were used to verify the spatial association of the phenomena and a retrospective space–time scan was performed. There were 32 041 confirmed cases of COVID-19 and 471 deaths. The non-randomness of cases (z score = 5.40; P < 0.001) and deaths (z score = 3.83; P < 0.001) were confirmed. Hotspots were identified for cases and deaths in the north and midwest regions of Brazil. Sixteen high-risk space–time clusters were identified for the occurrence of cases with a higher RR = 21.23 (P < 0.001) and four risk clusters for deaths with a higher RR = 80.33 (P < 0.001). These clusters were identified from 22 May and were active until 10 October 2020. The results indicate critical areas in the indigenous territories of Brazil and contribute to better directing the actions of control of COVID-19 in this population.
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As a high-burden neglected tropical disease, soil-transmitted helminth (STH) infections remain a major problem in the world, especially among children under five years of age. Since young children are at high risk of being infected, STH infection can have a long-term negative impact on their life, i...ncluding impaired growth and development. Stunting, a form of malnutrition in young children, has been long assumed as one of the risk factors in acquiring the STH infections. However, the studies on STH infection in children under five with stunting have been lacking, resulting in poor identification of the risk. Accordingly, we collected and reviewed existing related research articles to provide an overview of STH infection in a susceptible population of stunted children under five years of age in terms of prevalence and risk factors. There were 17 studies included in this review related to infection with Ascaris lumbricoides, Trichuris trichiura, hookworm, and Strongyloides stercoralis from various countries. The prevalence of STH infection in stunted children ranged from 12.5% to 56.5%. Increased inflammatory markers and intestinal microbiota dysbiosis might have increased the intensity of STH infection in stunted children that caused impairment in the immune system. While the age from 2 to 5 years along with poor hygiene and sanitation has shown to be the most common risk factors of STH infections in stunted children; currently there are no studies that show direct results of stunting as a risk factor for STH infection. While stunting itself may affect the pathogenesis of STH infection, further research on stunting as a risk factor for STH infection is encouraged.
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Organisation mondiale de la Santé. (2011). Planches pour le diagnostic microscopique du paludisme.
Covid-19 Social Policy Response Series / No.14
This report examines Ecuador’s social policy response to mitigate the Covid-19 pandemic’s effects and protect
vulnerable populations. It chronologically traces containment, closure policies, social policies and programmes
put in place following t...he announcement of Covid-19 as a global pandemic. A combination of external con-
straints and domestic structures, i.e. informality and weak coordination, led to truncated efforts in the healthcare
response, while persistent inequalities in access to technology and high levels of informality led to fragmented
education, labour policies and social protection responses. The report zooms into the Family Protection Grant
(Bono de Protección Familiar or BPF), a new social protection programme that covers informal workers, which
captures the difficulties in reaching unregistered populations amid lockdown and containment measures.
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We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized controlled trials (RCTs) as well as prospective and retro...spective cohort studies (CSs) with an internal or external control group that evaluated any adherence intervention and conducted a meta-analysis of their impact on TB treatment outcomes. Our search identified 7,729 articles, of which 129 met the inclusion criteria for quantitative analysis. Seven adherence categories were identified, including DOT offered by different providers and at various locations, reminders and tracers, incentives and enablers, patient education, digital technologies (short message services [SMSs] via mobile phones and video-observed therapy [VOT]), staff education, and combinations of these interventions.
https://doi.org/10.1371/journal.pmed.1002595
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