The growing understanding of how sequence information can contribute to improved public health is driving global investments in sequencing facilities and programmes. The falling cost and complexity of generating GSD provides opportunities for expanding sequencing capacity; however, challenges to wid...espread implementation remain. This document provides policy-makers and stakeholders with guidance on how to maximize the public health benefit of SARS-CoV-2 genomic sequencing activities in the short and long term as the pandemic continues to unfold. Practical considerations for the implementation of a virus genomic sequencing programme and an overview of the public health objectives of genomic sequencing are covered. This guidance focuses on SARS-CoV-2 but is applicable to other pathogens of public health concern.
more
Esta primeira versão de Medicamentos para prevenção da COVID-19: Orientação dinâmica da OMS aborda o uso de hidroxicloroquina para prevenção da COVID-19. Segue-se a publicação de uma análise sistemática e NMA que reuniu dados de seis estudos com 6.059 participantes que não tinham COVID-...19 e receberam hidroxicloroquina. Três estudos envolveram participantes que tiveram uma exposição conhecida a uma pessoa com infecção por SARS-CoV-2. Em resposta à divulgação dos dados de estudos, o GDG da OMS desenvolveu recomendações sobre a hidroxicloroquina, um agente anti-inflamatório que atua por meio do bloqueio dos receptores Toll-like, reduzindo a ativação das células dendríticas. É usada para tratar a artrite reumatoide e o lúpus eritematoso sistêmico. Tem um efeito antiviral contra muitos vírus in vitro, inclusive o SARS-CoV-2, mas não foi demonstrado um efeito antiviral clinicamente útil para nenhuma infecção viral.
more
-Covid-19 и беременность
-Особенности применения методов диагностики у беременных
-Особенности лечения covid-19 при беременности
-Акушерская тактика при covid-19
-Маршрути...ация беременных и их новорожденных
-Организация работы родовспомогательных учреждений в период пандемии covid-19
medical care for pregnant women, women in labour, newborns and newborns in case a COVID-19 coronavirus infection
more
Prevention, early diagnosis, and effective treatment are essential for the control and elimination of Neisseria gonorrhoeae as a public health problem. Currently, in Latin America and the Caribbean, treatment for gonorrhea infection is largely empiric and based on clinical diagnosis. In the Americas..., the high burden of new N. gonorrhoeae infections (estimated at 11 million new cases a year), the complexity of the disease epidemiology, and in many countries the limited resources, make it difficult to fully understand the burden of disease and the burden of antimicrobial resistance (AMR) in N. gonorrhoeae.
PAHO has developed this document to facilitate the navigation of available guidance and recommendations for N. gonorrhoeae AMR surveillance by public health and health care professionals, at the national and subnational levels, involved in designing, implementing, and/or strengthening AMR surveillance of N. gonorrhoeae and overall surveillance of sexually transmitted infections.
more
The outbreak of COVID-19 comes with unpredictable primary and secondary impacts on vulnerable and food-insecure populations across the world. Mortality and morbidity appear to be most acute for elderly people, and those with underlying health conditions. At the same time, the widely anti...cipated economic downturn could have a more devastating effect on the world’s poor than the virus itself
more
It is too early to know the full impact of COVID-19 on Africa. To date the experience has been varied. There are causes for concern, but also reasons for hope. Early estimates were pessimistic regarding the pandemic’s impact on the continent. But the relatively low numbers of COVID-19 cases report...ed thus far have raised hopes that African countries may be spared the worst of the pandemic. While the virus is present in all African countries, most countries have recorded fewer than 1,000 cases. The African Union acted swiftly, endorsing a joint continental strategy in February, and complementing efforts by Member States and Regional Economic Communities by providing a public health platform.
more
Este documento apresenta uma orientação provisória aos Estados Membros para uma rápida investigação de casos suspeitos de COVID-19 após um alerta ou sinal. Tem como propósito ser utilizada por autoridades de saúde locais, regionais ou nacionais como considerações para a investigação de ...casos de COVID-19. Não deve ser considerada como um guia abrangente para investigação do surto. Há orientações detalhadas disponíveis para a investigação de surto de outros patógenos respiratórios, incluindo o MERS-CoV e influenza. Maiores informações sobre a investigação de surto para a COVID-19 podem ser encontradas no OpenWHO website.Essa orientação pode ser implementada em diferentes países com vários recursos e padrões epidemiológicos e deve ser adaptada da forma mais adequada. Este documento tem como objetivo descrever os componentes específicos necessários para uma investigação. Ela é elaborada com base no conhecimento sobre a epidemia da COVID-19 e considerações semelhantes para outros patógenos respiratórios, incluindo o vírus MERS-CoV e influenza. A OMS continuará atualizando essas recomendações à medida que surgirem mais informações.
more
El ámbito de aplicación incluye a todos los trabajadores involucrados en trabajos de asistencia sanitaria (comprendidos los desarrollados en aislamiento, traslados, labores de limpieza, eliminación de residuos,etc.), así como los de transportes aéreo,marítimo y ferrocarril de ...larga distancia o internacional, los colectivos de rescate (bomberos, salvamento marítimo, policía, guardia civil, etc.), atención al público, hostelería, sector servicios, etc. Dado que el contacto con el virus puede afectar a entornos sanitarios y no sanitarios, corresponde a las empresas evaluar el riesgo de exposición y seguir las recomendaciones que sobre el particular emita el servicio de prevención,siguiendo las pautas y recomendaciones formuladas por las autoridades sanitarias.
more
While much progress has been achieved over the past year, the Region of the Americas has stubbornly remained the epicenter of the COVID-19 pandemic. PAHO is launching its 2021 COVID-19 Response Strategy and Donor Appeal to continue supporting Latin American and Caribbean countries and territories i...n their fight against COVID-19. This document outlines PAHO’s regional strategy for the year 2021 to sustain and scale-up the response to COVID‑19 pandemic in the Americas, suppress the community transmission of the virus and mitigate the longer-term health impact of the pandemic.
US$ 239 million is needed to support critical response efforts in the Americas between 1 January and 31 December 2021
more
Au cours d’une pandémie à COVID-19 une détérioration de la situation nutritionnelle des enfants et des femmes est très probablement liée à l’augmentation des prix des denrées alimentaires, la réduction de la disponibilité alimentaire et la baisse du revenu de la population suite au ral...entissement de la vie économique. Par ailleurs, la manière dont les interventions de nutrition sont offertes doit s’adapter à l’épidémie de COVID-19 pour éviter toute propagation de la maladie à COVID-19. C’est pourquoi, ce manuel est produit par le programme national de nutrition en collaboration avec le cluster nutrition et les autres partenaires pour donner des orientations sur la meilleure façon de poursuivre la mise en œuvre des interventions de nutrition en veillant aux mesures de prévention et contrôle de l’infection.
more
Accessed on 22.03.2020
Le Gouvernement du Burkina Faso a pris en compte au niveau du deuxième axe stratégique du Plan National de Développement Economique et Social (PNDES) 2016 – 2020 la nécessité de développer des actions allant dans le sens de la mitigation de l’impact du VIH sur les... populations. Deux CSLS successifs couvrant les périodes 2001-2005 et 2006 – 2010 ont été mis en œuvre contribuant de manière significative à baisser et à stabiliser la progression de la pandémie, en ramenant le taux de séroprévalence de 7,17% en 1997 à 0.90% en fin 2014 selon les estimations de l’ONUSIDA. Malgré cette évolution positive, le Burkina Faso demeure en situation d’épidémie généralisée. Ce même rapport mentionne que le nombre de PVVIH est estimé à 110.000, dont 57.000 femmes. 75.000 enfants sont estimés orphelins du fait du Sida. L’EDS IV réalisée en 2010 note que la prévalence en population générale présente des disparités selon le sexe. En effet, les femmes ont une prévalence de 1.2% contre 0.8% chez les hommes d’où un ratio H/F de 1.5 confirmant ainsi la théorie de la féminisation de l’infection pour des raisons à la fois socio-économiques et biologiques. Une étude récente conduite par le SP/CNLS ciblant les travailleuses du sexe (TS) a montré une prévalence au VIH de 16,19%, c’est à dire plus de 16 fois celle en population générale.
more
Guide de recommandations rapides 11 juin 2020
Depuis son identification en Chine en décembre 2019, le nouveau coronavirus responsable de la COVID‐19 s’est rapidement propagé pour causer une pandémie. Cette maladie se manifeste par des symptômes respiratoires non spécifiques de gravité var...iable et peut nécessiter une assistance respiratoire importante. Son diagnostic est actuellement confirmé grâce l’identification de l’ARN du virus grâce à un test de laboratoire utilisant la technique de la transcription inverse-amplification génique (en anglais, reverse transcriptase polymerase chain reaction, soit RT-PCR.
more
This book provides significantly expanded content and experience in relation to a broader stewardship context- for example, stewardship in specific populations, different countries as well as the role of different professions in stewardship to political and media engagement. We hope this book has so...mething to offer everyone practicing in this area. Therefore, The British Society for Antimicrobial Chemotherapy [BSAC] in collaboration with ESGAP are very pleased to present this e-book on Global Antimicrobial Stewardship that is relevant to health care professions working in preventing and managing infection across the healthcare communities and health care facilities. It aims to support health care professionals, or teams, or policy makers interested in learning about bringing the principles of stewardship to the bed side
more
Personne ne se rend dans un établissement de soins de santé pour tomber malade. On s’y rend pour aller mieux, pour accoucher, pour se faire vacciner. Cependant, des centaines de millions de gens sont confrontés à un risque accru d’infection quand ils se font soigner dans des établissements ...de santé où les services de première nécessité font défaut, y compris les services d’approvisionnement en eau, d’assainissement et d’hygiène (WASH) et les services de gestion des déchets médicaux. Non seulement l’absence de services WASH dans les établissements de santé compromet la sécurité sanitaire des patients et leur dignité, mais il peut éventuellement exacerber la propagation d’infections résistant aux antimicrobiens et compromettre les efforts faits en vue de l’amélioration de la santé maternelle et infantile.
more
Integrated management of childhood illness. The last update was in the IMCI chart booklet in 2014, but since then there have been significant updates on the management of sick young infant (SYI) aged up to 2 months. This 2019 update of the sick young infant section Management of the sick young infan...t age up to 2 months: IMCI chart booklet. supersedes the 2014 IMCI chart booklet. The new updates reflect the recent guidelines on Managing possible serious bacterial infection (PSBI) in young infants when referral is not feasible published in 2015. It includes assessment, classification and referral of SYI with PSBI; and outpatient treatment of SYI with local infection or fast breathing (pneumonia) in infants 7-59 days old. Other updates include: a new section on how to reassess, classify and treat SYI with PSBI when referral is not feasible in outpatient health facilities by IMNCI trained health workers; changes in assessment and management of young infants for HIV infection; and identification of infants less than 7 days of who need Kangaroo Care.
more
Poor quality health services are holding back progress on improving health in countries at all income levels.
Today, inaccurate diagnosis, medication errors, inappropriate or unnecessary treatment, inadequate or unsafe clinical facilities or practices, or providers who lack adequate training an...d expertise prevail in all countries.
The situation is worst in low and middle-income countries where 10 percent of hospitalized patients can expect to acquire an infection during their stay, as compared to seven percent in high income countries. This is despite hospital acquired infections being easily avoided through better hygiene, improved infection control practices and appropriate use of antimicrobials.. At the same time, one in ten patients is harmed during medical treatment in high income countries.
more
Monkeypox is an emerging viral zoonosis with symptoms similar to those observed in smallpox patients, although less severe. Since the global eradication of smallpox in 1980, monkeypox has emerged as the most important orthopoxvirus in humans. The Advisory Committee on Variola Virus Research (ACVVR) ...which meets annually to oversee smallpox research has highlighted the importance of diagnostics that could distinguish between variola and other strains of orthopoxviruses, including monkeypox virus. The ACVVR encourages the positive effects of current smallpox research on all orthopoxviruses, specifically monkeypox, such as the development of diagnostic tools.
more
La surveillance épidémiologique est un processus continu de collecte, d’analyse et de diffusion d’informations pour la prise d’actions de riposte. Les activités de surveillance épidémiologique sont mises en œuvre au Sénégal selon la stratégie SIMR (Surveillance Intégrée de la Maladi...e et Riposte) et suivant le RSI (version 2005). Cependant, très souvent les données de surveillance des maladies, surtout au niveau communautaire, ne sont pas toujours bien enregistrées, notifiées et analysées. Aujourd’hui, les maladies transmissibles émergentes et ré-émergentes comme la maladie à virus Ebola (MVE), constituent une menace importante pour la santé et le bien-être de nos communautés.
more
Objective: The study aimed to describe the current epidemiological, clinical and immunological profile of newly
detected HIV - positive patients in Northern Benin by 2016. Methods: It was a prospective study conducted from May 2 to
October 31, 2016 on three main sites of care of people living with... HIV (PLHIV) in the department of Borgou in Benin. All
new cases of HIV infection have been systematically and comprehensively recruited. Initial epidemiological, clinical and
immunological data were collected using a questionnaire. These data were entered and analyzed using the Epi Info 7 software.
Results: In total, 185 adults (68 male and 117 female) newly screened HIV positive were included in this study. The middle age
was 36.2 ± 10.9 years and the sex ratio was 0.6 One hundred and thirty-five patients (73%) were between 25 and 50 years old.
In terms of the profession, 132 patients (71.3%) were engaged in liberal activities (craftmen, traders and retailers). The
majority was schooled (113 or 61.1%) and resided in urban areas (146 or 79%). One hundred and sixteen patients lived in
couple (62.7%) with an average monthly income estimated at 70 US Dollars. Clinically, 123 patients (66.5%) were in WHO
stage III. The body mass index was over 18.5 kg/m2 in 124 patients (67%). The median number of TCD4 lymphocytes was
254.5 cells/ml and 25 patients (13.5%) had a number of CD4 over 500 cells/ml. HIV1 was really predominant (97.8%). Most
patients (152 or 82.2%) had been screened for clinical suspicion. Conclusion: HIV infection in Benin remains the prerogative
of young, female, educated and poor people. Screening is delayed and hence the need to develop innovative strategies for early
more
Rapport de Suivi de la Déclaration de Politique du Bénin
À l’instar des autres pays de la sous-région, le Bénin est un pays à épidémie mixte. Depuis 2006, la prévalence du VIH s’est stabilisée à 1,2% dans la population générale. Malgré cette tendance à la stabilisation, il exi...ste des poches de concentration de fortes prévalences au sein de certaines populations clés plus exposées aux risques d’infection, notamment les professionnelles de sexe (PS), les détenus, les HSH et les CDI.
more