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Current Treatments to Control African Trypanosomiasis and One Health Perspective

Venturelli, A.; Tagliazucchi, L.; Lima, C.; Venuti, F. et al. MDPI Microorganisms (2022) CC
Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei. Despite important advances in the reduction or disappearance of HAT cases, AAT represents a risky reserv... more
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Breaking the silence an Opportunity for Patients with Chagas Disease

Moriana, S.; Oritz, G.; Fanjul, G. Chagas Coalition (2016) CC
Not long ago, on the occasion of the 100th anniversary of the discovery of Chagas disease, several campaigns denounced the scant progress has been made in diffrent spheres- medical, scientific and politcal- but major challanges still remain. This is an appropriate time to celebrate what has been ach... more
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IDF Diabetes Atlas

International Diabetes Federation (2021) CC2
Key global findings 2021 The IDF Diabetes Atlas 10th edition reports a continued global increase in diabetes prevalence, confirming diabetes as a significant global challenge to the health and well-being of individuals, families and societies.
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Global Initiatibe for Chronic Obstructive Lung Disease - Pocket Guide 2023

Global Initiative for Chronic Obstructive Lung Disease – GOLD (2023) CC2
Chronic Obstructive Pulmonary Disease (COPD) is now one of the top three causes of death worldwide and 90% of these deaths occur in low- and middle-income countries (LMICs). More than 3 million people died of COPD in 2012 accounting for 6% of all deaths globally. COPD represents an important public... more
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European Respiratory Society guidelines for the diagnosis of asthma in adults

Renaud, L.; Imran, S.; Inigo, O., et al. European Respiratory Journal (2022) CC
Although asthma is very common, affecting 5–10% of the population, the diagnosis of asthma in adults remains a challenge in the real world, which results in both over- and under-diagnosis. A taskforce was set up by the European Respiratory Society to systematically review the literature on the dia... more
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Task-shifting to improve asthma education for Malawian children: a qualitative analysis

Nkhalamba, L.; Rylance, S.; Muula, S. A. et al. Human Resources for Health (2021) CC
Background Asthma education, a key component of long-term asthma management, is challenging in resource-limited settings with shortages of clinical staff. Task-shifting educational roles to lay (non-clinical) staff is a potential solution. We conducted a randomised controlled trial of an enhanced a... more
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Surveillance and control of Anopheles stephensi

World Health Organisation (WHO) (2024) C_WHO
Anopheles stephensi is an invasive mosquito species which has been found spreading across Africa. While this species presents a new challenge for malaria control on the continent, its surveillance and management have been ongoing in Asia for many years. This document aims to summarize key lessons fr... more
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Global spending on health: rising to the pandemic’s challenges

World Health Organization WHO (2022) C_WHO
The results of the report clearly show that in 2020, a year dominated by the emergence of COVID-19 and its associated health and economic crises, governments around the world rose to the challenge. Sharp increases in government spending on health at all country income levels underpinned the rise in ... more
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IRC Ethiopia strategic plan 2022-2025

Internationam Water and Sanitation Centre (2023) CC
After introducing Ethiopia's WASH sector challenges and trends, the plan describes IRC Ethiopia's vision and strategy which draws from IRC and Water For People's joint framework - Destination 2030. It then details the organisational changes and business development needed to implement the strategic ... more
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Identifying common opportunistic infections among people with advanced HIV disease

World Health Organization WHO (2024) CC
Advanced HIV disease (defined in persons living with HIV with a CD4 cell count of <200cells/mm3 or presenting with a WHO Stage 3/4 AIDS-defining illness) poses a challenge to many countries globally and is responsible for significant mortality and morbidity among people living with HIV. In 2017, WHO... more
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Tuberculosis Research Funding Trends 2005-2020

World Health Organisation (WHO) (2021) C_WHO
Previous advocacy efforts have achieved tangible goals in terms garnering political commitments to increase financing for TB—as seen at the 2018 UN High-Level Meeting on TB. The challenge now is to ensure that these commitments are actually met within a global biomedical research ecosystem that... more
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Clinical Management of Yellow Fever in the Region of the Americas. Experiences and Recommendations for Health Services

Pan American Health Organisation PAHO (2023) CC
The waves of yellow fever transmission in the Region of the Americas in 2016–2018 involved the largest number of human and epizootic cases to be reported in several decades. Yellow fever is a serious viral hemorrhagic disease that poses a challenge for health professionals. It requires early recog... more
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Molecular and Clinical Aspects of Chronic Manifestations in Chagas Disease: A State-of-the-Art Review - ProQuest

Medina-Rincón G.J., Gallo-Bernal S., Jiménez P.A. et al Pathogens (2021) C2
Chronic manifestations of Chagas disease present as disabling and life-threatening conditions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mechanisms underlying Trypanosoma cruzi’s infection and the host-parasit... more
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A primary health care approach to obesity prevention and management in children and adolescents: policy brief

World Health Organisation (WHO) (2023) C_WHO
Obesity in all age groups, including children and adolescents, is a public health challenge across all settings. Obesity is now classified as a complex multifactorial chronic disease and not just a risk factor for other noncommunicable diseases and comorbidities. Recognizing the significance of prim... more
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Antibiotic Guidelines, 2019 (First edition) - Myanmar

World Health Organization WHO (2019) C_WHO
This is the first edition of Empiric Antibiotic Guidelines, as a guidance to all medical practitioners at North Okklapa General & Teaching Hospital. Antibiotics are critical in the management of infection and can have a significant impact in reducing morbidity and mortality. Emerging antimicrobia... more
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Worldwide Control and Management of Chagas Disease in a New Era of Globalization: a Close Look at Congenital Trypanosoma cruzi Infection.

Abras A., Ballart C., Fernández-Arévalo A., et al. Clinical Microbiology Reviews (2022) CC
Population movements have turned Chagas disease (CD) into a global public health problem. Despite the successful implementation of subregional initiatives to control vectorial and transfusional Trypanosoma cruzi transmission in Latin American settings where the disease is endemic, congenital CD (cCD... more
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Preventing Child and Maternal Deaths: A Framework for Action in a Changing World 2023-2030

US Agency for International Development USAID (2023) CC
Improving the survival chances and quality of life of women, newborns, and children remains an urgent global challenge. Since 2012, substantial progress has been made in reducing maternal and under-5 deaths, and a only handful of countries are on target to meet the SDG targets in 2030. Yet, 5 millio... more
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Safe consultations with survivors of violence against women and girls

UN Women (2022) C_WHO
One of the principles underpinning the delivery of all essential services and coordination of those services is the “survivor-centered approach”, which places the human rights, needs, and wishes of women and girl survivors at the centre of service delivery. A key challenge faced by many entit... more
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Медики провели близько 300 зустрічей у центрах перебування ВПО, де розповіли про імунізацію

UN Children's Fund UNICEF (2022) C_UNICEF
Медики провели близько 300 зустрічей у центрах перебування ВПО, де розповіли про імунізацію 04 Липень 2022 Forty-eight health workers have been visiting internally displaced persons’ (IDP) centres in Ukraine as part... more
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The Building Blocks of a Circular Economy: USAID’S Local Systems Approach to Reducing Ocean Plastic Pollution

USAID (2022) CC
Ocean plastic pollution has reached crisis level: every minute, more than an entire garbage truck of plastic makes its way into the world’s oceans—roughly 11 million metric tons annually. While plastic waste presents an immediate threat to marine wildlife and ecosystems, this global challenge al... more