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1
Tuberculosis (TB) remains a serious public health threat in South Africa and is the
leading cause of death in people living with HIV (PWH). Pre-hospital and early in-
hospital mortality is of particular concern in PWH. Significant progress has been made
to date, but a monumental effort is require
...
d to reach the END TB target of zero deaths
due to TB by 2035. One of the measures would be to curb early in-hospital mortality
due to TB. This goal provided impetus for the development of this package of care.
more
This issue brief provides information about TB and HIV clinical trials and research programs
impacted by U.S. government funding disruptions, and proposes urgent actions that
donor agencies, governments, and philanthropies can take to preserve scientific advances
underway and prevent the collapse
...
of TB and HIV medical research in South Africa
more
FORTBILDUNG – SCHWERPUNKT TUBERKULOSE HIV & More
Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV K-19 Tuberculosis/HIV Coinfection
Updated: September 12, 2024 Key Considerations and Recommendations
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
...
ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
July 2023 version .The 2023 ART guideline introduces simplified ART provision and harmonised methods of management of children, adolescents and adults, as well as pregnant women living with HIV/AIDS, TB and other common opportunistic infections.
The guidelines also provide guidance on the use of D
...
olutegravir (DTG) dispersible tablets for children from 3kg and 4 weeks old.
These guidelines have been revised with the Differentiated Models of Care SOPs to ensure simultaneous consideration and alignment of clinical, adherence and service delivery updates.
more
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
This is the 2025 draft Malawi Guidelines for Syndromic Management of Sexually Transmitted Infections which is yet to be approved by the SMT.
In: Antenatal Care, Maternal Care, Under 5 Clinics, Family Planning Clinics and HIV Exposed Child Follow Up.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replaces all previous editions of the Malawi Antiretrovir
...
al therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
more
Essential triple EMTCT services include testing for HIV, syphilis and HBV in ante-
natal care (ANC) settings; prompt and efficacious interventions to treat women
who test positive; prevent transmission of any of the infections to their children;
counseling for women and their partners to reduce t
...
ransmission risk and ensure
appropriate treatment; encourage clean and safe delivery; appropriate follow
up of exposed infants including provision of HBV vaccine birth dose; promoting
optimal infant-feeding; and lifelong treatment and care for mothers living with
HIV or those eligible for treatment for hepatitis B infections and treatment for
syphilis.
more
Technical Document
Panels Recommendation Updated Dec 2024
What works?
Bhana A et al. Journal of the International AIDS Society 2021, 24(S2):e25713
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes
organization of adolescent-friendly services to guide heath management teams and health
care workers (HCWs) on their roles. It also outlines important aspects to consider when
offering comprehensive care to adolescents an
...
d their parents/caregivers at health facilities
and in the community. Comprehensive care should include the provision of quality clinical
and psychosocial support (PSS) services with clear linkages to the community. These
services need to be adolescent-friendly at any health facility with clear prescription of
minimal standards, and has to be integrated into existing services at the health facility
more
Journal of Adolescent Health 2022 1-16
Policy Brief
International Journal of Integrated Care, 2025; 25(2): 5, 1–12. DOI: https://doi.org/10.5334/ijic.8920. Community-based intervention support plays a crucial role in enhancing
the lives of orphans and vulnerable children in Africa. Community-based intervention
support needs to be integrated into
...
a wider social service system. Further research
focusing on the cost of community-based intervention support and successful
programs for mainstreaming community-based intervention into a wider social
system is needed.
more
Guidance for Orphans and Vulnerable Children Programs