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3
Malaria in children presents significant clinical challenges, with variations in presentation based on the malaria parasite involved and the child's underlying health conditions. The World Health Organization reports high incidence rates, particularly in sub-Saharan Africa, and emphasizes the import
...
ance of effective treatment strategies. First-line treatment often involves Artemether-Lumefantrine (ALu), while severe malaria requires careful management and the use of intravenous Quinine. Management protocols emphasize early diagnosis and the monitoring of severe complications to reduce mortality.
more
4th edition, Reference Manual
Pillar 3 of the Global technical strategy for malaria 2016–2030 calls for the transformation of malaria surveillance into a core intervention in all malaria-endemic countries, as well as in countries which have eliminated malaria but remain susceptible to re-establishment of transmission. This ref
...
erence manual covers subjects that are relevant to both settings.
The target readership of this manual includes staff working in ministries of health, national malaria programmes and health information systems; partners involved in malaria surveillance; and WHO technical officers who advise countries on malaria surveillance.
more
This Malaria Surveillance Assessment Toolkit implementation reference guide is a comprehensive reference document, as well as a step by-step guide. It aligns and adapts available tools into a single set of standardized tools, which can be used to conduct malaria surveillance assessments across all t
...
ransmission settings. Use of these standardized tools allows comparison of results between countries and within the same country over time, enabling countries to track their progress towards surveillance system strengthening.
more
2nd edition. The purpose of this document is to present updated standardized protocols that P. falciparum-endemic countries can use to determine the prevalence of parasites with pfhrp2/3 gene deletions causing negative HRP2 RDT results among symptomatic falciparum patients. The findings should be us
...
ed to guide RDT selection; more specifically when to shift away from exclusive use of HRP2 to detect P. falciparum infections.
more
This practical document is available to support programmes and partners to design and implement risk communication strategies to achieve high uptake of malaria vaccination.
Preferred product characteristics and clinical development considerations
Malaria vaccines: the 60‑year journey of hope and final success—lessons learned and future prospects
Tropical Medicine and Health (2023) 51:29
Two malaria vaccines are currently WHO prequalified and recommended1 for use to prevent
P. falciparum malaria in young children, the RTS,S/AS01 vaccine, currently manufactured by
GlaxoSmithKline (GSK), and the R21/Matrix-M vaccine, manufactured by Serum Institute of India
Pvt (SII)
Fragile Beginnings. The Fragile Beginnings series examines the growing body of research on the unique vulnerabilities of children: in utero and at birth, during infancy and childhood and throughout adolescence. Its purpose is to enable evidence-based advocacy and action on children’s environmental
...
health
more
Malaria Journal (2021) 20:190
National Malaria Social and Behavior Change (SBC) Strategy 2024–2028
Programme National de Lutte contre le Paludisme (PNLP) – République Démocratique du Congo (RDC)
Ministère de la Santé Publique, Hygiène et Prévention de la RDC
(2024)
C2
La République démocratique du Congo (RDC) occupe la 2ème place en termes de nombre de cas de paludisme et de décès associés dans le monde (12% des cas et 13% des décès), et représente à elle seule 54,6% des cas en Afrique centrale (OMS, Rapport Mondial sur la situation du paludisme 2022).
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La coordination des activités de changement social et comportemental entre les partenaires dans le pays reste un défi.
Une stratégie nationale solide de lutte contre le paludisme est essentielle pour coordonner et amplifier les efforts de lutte contre le paludisme dans toute la RDC. Breakthrough ACTION a joué un rôle central dans l’élaboration et la finalisation de la Stratégie nationale de SBC contre le paludisme 2024-2028, qui s’aligne sur le Plan stratégique national de lutte contre le paludisme 2024-2028. Cette mise à jour de la Stratégie nationale de lutte contre le paludisme intègre des conseils sur l’introduction du vaccin antipaludique en RDC, des informations clés issues des récentes études de recherche sur le paludisme menées par Breakthrough ACTION, ainsi que des messages de santé prioritaires actualisés destinés aux hommes, aux prestataires de services, aux femmes enceintes et aux femmes ayant des enfants de moins de cinq ans.
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The framework recommends expanded coverage of malaria diagnostic and treatment services, intensified vector control to drive down transmission, strengthened malaria surveillance, and increased transborder collaboration, especially in terms of efforts to control the sale and use of artemisinin monoth
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erapies. Since it is unlikely that national malaria control programs will be able to implement all the activities described in this framework simultaneously, a list of suggested priority activities has been included in the Annex.
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SuperBetter Children is a health and wellbeing curriculum designed to be integrated into school programmes or offered as an extracurricular activity.
The document “Malaria Prophylaxis for Travellers: Guideline for Healthcare Workers” (2019) from Sri Lanka provides guidance for healthcare providers on preventing malaria among travelers to endemic areas.
It explains that since Sri Lanka was certified malaria-free in 2016, the main risk comes f
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rom imported cases, mostly Sri Lankan travelers. The document emphasizes assessing travelers’ risk, advising on mosquito bite prevention, and prescribing appropriate chemoprophylaxis like chloroquine, mefloquine, atovaquone-proguanil, or doxycycline depending on destination and traveler profile.
It highlights that children, pregnant women, and immunocompromised individuals are particularly at risk, and stresses adherence to medications and protective measures. Special instructions are given on handling missed doses, long-term prophylaxis, and managing side effects. Overall, the guideline aims to maintain Sri Lanka’s malaria-free status by preventing reintroduction through well-informed traveler care.
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The Manual for Indoor Residual Spraying in Urban Areas for Aedes aegypti Control is intended not only for operational personnel and middle and senior management of programs responsible for the prevention and control of Aedes-borne diseases, but also for the academic community involved in Aedes resea
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rch, private pest control personnel, and the general public.
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O Manual para aplicação de borrifação residual em áreas urbanas para o controle do Aedes aegypti não se dirige apenas ao pessoal operacional e aos gerentes e gestores de nível médio dos programas de prevenção e controle das doenças transmitidas pelo Aedes, mas também à comunidade acadê
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mica ligada à pesquisa operacional sobre BRI-Aedes, aos controladores de pragas privados e ao público em geral.
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Ce manuel est destiné aux prestataires de soins chargés de la prise en charge des cas de paludisme simple et grave au niveau des structures de santé. C’est un document de référence facile d’utilisation, fournissant des connaissances et des compétences utiles aux agents de santé prenant e
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n charge les cas de paludisme.
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This training module on malaria case management has been developed to support the staff involved in malaria control and elimination programmes in the effective organization of malaria diagnosis and case management services
