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Clinical Presentation of T.b. rhodesiense Sleeping Sickness in Second Stage Patients from Tanzania and Uganda

Kuepfer, I.; Hhary, EP.; Mpairwe, A.; Edielu, A.; Burri, C.; Blum, JA. PLOS Neglected Tropical Diseases (2011) CC
A wide spectrum of disease severity has been described for Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense (T.b. rhodesiense), ranging from chronic disease patterns in southern countries of East Africa to an increase in virulence towards the north. However, only limited d... more
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Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan

Bukachi, SA.; Mumbo, AA.; Alak, ACD.; Sebit, W.; Rumunu, J. et al. PLOS Neclected Tropical Diseases (2018) CC
A clear understanding of the knowledge, attitudes and practices (KAP) of a particular community is necessary in order to improve control of human African trypanosomiasis (HAT).New screening and diagnostic tools and strategies were introduced into South Sudan, as part of integrated delivery of primar... more
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Elimination of human African trypanosomiasis as public health problem

World Health Organization WHO Team Control of Neglected Tropical Diseases (2022) C_WHO
More countries eliminate human African trypanosomiasis as a public health problem: Benin and Uganda (gambiense form) and Rwanda (rhodesiense form) Human African trypanosomiasis (HAT), or sleeping sickness, transmitted by tsetse flies in sub-Saharan Africa, is a life-threatening disease that afflict... more
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Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy

Tirados, I.; Esterhuizen, J.; Kovacic, V.; Mangwiro, TNC.; Vale, GA et al. PLOS Neglected Tropical Diseases (2015) CC
Sleeping sickness is controlled by case detection and treatment but this often only reaches less than 75% of the population. Vector control is capable of completely interrupting HAT transmission but is not used because of expense. We conducted a full scale field trial of a refined vector control tec... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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Human African Trypanosomiasis (HAT) - Sleeping Sickness

Drugs for Neglected Diseases initiative DNDi (2008) C2
At the forefront of DNDi’s efforts to develop new treatments is the need to understand the realities and treatment needs of patients and health care staff in the field. The ultimate goal for human African trypanosomiasis (HAT) is a truly simplified treatment which can be orally administered, impl... more
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Community Assessment For Public Health Emergency Response (Casper) Toolkit; third edition 3.2
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Centers for Disease Control and Prevention CDC (2019) CC
2nd edition
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Operational considerations for the provision of the HIV continuum of care

European Centre for Disease Prevention and Control ECDC (2022) C1
This document provides an overview of key considerations for the provision of the HIV continuum of care in the context of displaced people from Ukraine in the EU/EEA. This document has two aims: firstly, to outline what is known of the Ukrainian HIV epidemic, and secondly, to use the HIV continuum o... more
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Interim advice for public health authorities on summer events during the monkeypox outbreak in Europe, 2022

European Centre for Disease Prevention and Control ECDC (2022) C1
14 June 2022. The aim of this document is to provide concise advice to public health authorities and guide their prevention, awareness-raising and behaviour change interventions before, during and after upcoming summer events.
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Guidance for the prevention and control of COVID-19 in temporary reception centres in the context of the large numbers of people fleeing Ukraine
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European Centre for Disease Prevention and Control ECDC (2022) C1
This document offers public health guidance for the prevention and control of COVID-19 in reception centres, and other temporary accommodation facilities, in the context of the mass influx of Ukrainian people into the European Union (EU), the European Economic Area (EEA) and the Republic of Moldova.
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Implementation Guide for COVID-19 Vaccines in Africa
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African Union; Africa CDC Centres for Disease Control and Prevention; World Health Organization WHO, et al. (2021) C1
“Guide to facilitate the implementation of the WHO/UNICEF “Guidance on developing a national deployment and vaccination plan for COVID-19 vaccines” for Africa t contains action-oriented lists of critical topics to address and checklists tailored to the context of African Union Member States. ... more
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African Union Framework for Antimicrobial Resistance Control 2020–2025
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African Union; Africa CDC Centres for Disease Control and Prevention; World Health Organization WHO, et al. (2021) CC
Reports of antimicrobial-resistant (AMR) microorganisms are increasing globally, threatening to render existing treatments ineffective against many infectious diseases. In Africa, AMR has already been documented to be a problem for human immunodeficiency virus (HIV) and the pathogens that cause mala... more
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Guidance on Emergency Expedited Regulatory Authorisation and Access to COVID-19 Vaccines in Africa

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1
Taking the whole of Africa approach to fighting the COVID-19 pandemic has and will continue to require coordinated efforts from multiple stakeholders from across the continent. Africa CDC would like to acknowledge the deep partnership and continued support of AUDA-NEPAD, AVAREF, WHO AFRO, the Bill a... more
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Cadre de l'Assurance Qualité Test de Diagnostic Rapide de l'Antigene COV-2-SARS
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African Union; Africa CDC Centres for Disease Control and Prevention; AMREF; ASLM; et al. (2021) CC
ASLM in collaboration with the Africa Centres for Disease Control and Prevention, and in partnership with the Clinton Health Access Initiative, Amref and Last Mile Health present the Quality Assurance Framework for SARS-CoV-2 Antigen Rapid Testing for Diagnosis of COVID-19. This framework aims to pr... more
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Методы обнаружения и описания вариантов SARS-CoV-2 – первое обновление. 20 декабря 2021 г.

European Centre for Disease Prevention and Control ECDC; WHO Europe (2021) C1
20 Dec. 2021
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African Antibiotic Treatment Guidelines for Common Bacterial Infections and Syndromes – Final Report

Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy (2021) CC
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Lignes directrices africaines sur le traitement antibiotique des infections et des syndromes bacteriens courants

Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy (2021) CC
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COVID-19 infection prevention and control for primary care, including general practitioner practices, dental clinics and pharmacy settings. First Update

European Centre for Disease Prevention and Control ECDC (2020) C1
Infection prevention and control (IPC) practices are of critical importance in protecting the function of healthcare services at all levels and mitigating the impact on vulnerable populations. Although the management of possible COVID-19 cases is usually guided by national policies for specific heal... more
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Guidance on easing lockdown

Africa CDC Centers for Disease Control and Prevention (2020) CC
In response to the first cases of coronavirus disease 2019 (COVID-19) reported on the continent, many African Union Member States implemented large-scale public health and social measures (PHSM) rapidly. These measures were aimed at reducing transmission and the number of new cases being reported, p... more
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COVID -19 Outbreak Guidelines for Setting up Isolation Facility/Ward

Ministry of Health & Family Welfare Government of India; Na􏰀tional Centre for Disease Control Ministry of Health & Family Welfare Government of India; Na􏰀tional Centre for Disease Control (2020) C2
Accessed: 16.04.2020