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1
Early Warning and Response to Outbreaks and other Public Health Events: A Guide provides practical guidance for strengthening early warning functions within existing public health surveillance systems in WHO’s South-East Asia Region. The document explains how countries can detect, verify, and resp
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ond rapidly to outbreaks and other unusual public health events in line with the International Health Regulations (2005). It describes the five key steps of an Early Warning and Response (EWAR) system—information collection, signal detection, event verification, response, and communication—and outlines how to set alert thresholds, identify signals, and ensure timely reporting. The guide also includes recommendations for monitoring and evaluating system performance to improve timeliness, sensitivity, and overall effectiveness in preventing and controlling public health threats.
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This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
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The document “Guidelines for the Investigation and Control of Disease Outbreaks” provides practical guidance for public health professionals on how to detect, investigate, and manage outbreaks of communicable diseases. It describes the key steps of outbreak investigation, including confirming th
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e outbreak, establishing a case definition, collecting epidemiological and laboratory data, identifying the source and mode of transmission, and implementing control measures. The guidelines also explain how to organize outbreak response teams, communicate findings, and document results in outbreak reports. Overall, the document aims to support systematic and effective outbreak investigations in order to control disease spread and protect public health.
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Outbreak Investigation, Response and Control – Module 8. Integrated Disease Surveillance Project: Training Manual for State & District Surveillance Officers
Integrated Disease Surveillance Project (IDSP)
Ministry of Health and Family Welfare, Government of India
(2005)
C2
The document “Outbreak Investigation, Response and Control – Module 8” is a training module from the Integrated Disease Surveillance Project (IDSP) designed to guide health officials in investigating and managing disease outbreaks. It explains the basic principles and steps of outbreak investi
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gation, including detecting unusual increases in disease cases, confirming diagnoses, collecting and analyzing epidemiological data, and identifying the source and mode of transmission. The module also describes appropriate control and prevention measures, emphasizes timely reporting and coordination within the surveillance system, and aims to strengthen the capacity of public health workers to effectively respond to infectious disease outbreaks at the district and state levels.
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Organisation mondiale de la Santé (2019). Guide pratique pour l’élaboration et la conduite d’exercices de simulation destinés à tester et à valider les plans de préparation à la grippe pandémique. Organisation mondiale de la Santé.
Guide to revision of national pandemic influenza preparedness plans - Lessons learned from the 2009 A(H1N1) pandemic
Brown C., Ciotti M., Hegermann-Lindencrone M., et al
European Centre for Disease Prevention and Control (ECDC), WHO Regional Office for Europe
(2017)
C_WHO
The document “Guide to revision of national pandemic influenza preparedness plans – Lessons learned from the 2009 A(H1N1) pandemic” provides guidance for countries on how to improve and update their national pandemic preparedness plans. It is based on lessons learned from the 2009 influenza pa
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ndemic and aims to help governments strengthen their readiness for future pandemics. The report outlines key components of effective pandemic planning, including risk assessment, coordination between sectors, communication strategies, healthcare system preparedness, vaccination and antiviral strategies, and business continuity planning. It also emphasizes the importance of international cooperation and flexible planning that can adapt to different pandemic scenarios. Overall, the guide serves as a framework to support countries in developing stronger, more coordinated responses to future influenza pandemics.
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The document “Mpox Continental Response Plan 2.0” outlines the strategy developed by the Africa Centres for Disease Control and Prevention (Africa CDC) in collaboration with the World Health Organization (WHO) to respond to the ongoing mpox outbreak across Africa. The plan describes coordinated
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actions to strengthen surveillance, laboratory capacity, case detection and contact tracing in affected countries. It also focuses on improving access to vaccines, diagnostics and treatment, supporting healthcare systems, and enhancing risk communication and community engagement. In addition, the document highlights the importance of regional and international cooperation, resource mobilization and technical support to help African countries control the outbreak and prevent further spread. Overall, the plan serves as a continental framework to guide a coordinated public health response to mpox in Africa.
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Morbidity and Mortality Weekly Report MMWR / March 10, 2023 / Vol. 72 / No. 10
Southern African Journal of HIV Medicine
Why we need Targets for 2025.
1.2020 Fast Track targets will soon elapse; 2. Current UNAIDS strategy concludes in 2021; 3. Informs possible UN General Assembly Special Session on AIDS in 2021; where a new Political Declaration on AIDS would be adopted; 4. Informs the strategies of other organisatio
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ns (Global Fund, PEPFAR); . An updated set of programmatic targets for 2025 in needed to keep us on
track for 2030
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This document consolidates, for the first time, WHO recommendations on the prevention, testing, treatment and monitoring of hepatitis B and C, and includes testing strategies for hepatitis D. Drawing on a decade of evidence-based guidance issued between 2015 and 2025, it provides a single, practical
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handbook to support global progress toward eliminating viral hepatitis by 2030.
The document also highlights simplified service delivery models that promote decentralization, integration with primary care and related programmes such as HIV and tuberculosis, as well as task sharing and differentiated care to expand access and improve efficiency. It further underscores the need for robust data and monitoring systems to support effective programme implementation.
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Le présent document a été publié pour la première fois en 2006 (Lewis et de Bernis, 2006). Il est vraiment remarquable de le lire aujourd’hui1 et de constater à quel point la situation de la fistule a changé. En 2006, ce travail original et novateur a mis en évidence la fistule obstétrica
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le en tant que problème urgent de santé publique et a permis d’élaborer les premiers conseils pratiques pour les personnes impliquées dans les soins aux femmes souffrant de cette affection. En 2018, la communauté internationale a appelé à l’élimination de la fistule obstétricale dans un délai de dix ans, s’inscrivant ainsi en droite ligne avec l’Agenda 2030 pour le développement durable et ses 17 objectifs mondiaux.
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The document explains how Unitaid contributes to strengthening global pandemic prevention, preparedness, and response, particularly in low- and middle-income countries. It highlights lessons from the COVID-19 pandemic, including inequalities in access to health tools, and emphasizes the need for bet
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ter coordination, stronger health systems, and increased investment in research and development. The text describes Unitaid’s role in improving access to diagnostics, treatments, and medical oxygen, supporting regional manufacturing, and working with global partners to ensure faster and more equitable responses to future health emergencies.
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The document is a report by an expert group that presents a framework for improving future pandemic preparedness and emergency response, particularly in the context of India but with relevance to global health systems. It analyzes lessons learned from COVID-19 and past epidemics, identifies key weak
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nesses in areas such as governance, surveillance, data management, research, and coordination, and proposes a comprehensive strategy to address them. The report emphasizes the importance of early detection, strong public health infrastructure, coordinated governance, scientific innovation, and international collaboration. A central idea is the ability to respond effectively within the first 100 days of an outbreak by having systems, resources, and policies already in place. Overall, it aims to strengthen resilience and ensure faster, more efficient responses to future health crises.
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The document is a practical handbook developed by the European Centre for Disease Prevention and Control (ECDC) that provides guidance on how to design, plan, conduct, and evaluate simulation exercises in public health settings. Its main purpose is to help organisations improve their preparedness an
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d response to communicable disease outbreaks by using structured exercises as a training and evaluation tool. The handbook explains different types of exercises, outlines the steps involved in organising them, and highlights the importance of clear objectives, coordination, and evaluation. Overall, it aims to strengthen emergency preparedness by enabling organisations to identify weaknesses, improve collaboration, and enhance their ability to respond effectively to public health crises.
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Ukraine. Sitrep 2026: Fifth year of war: deepening humanitarian needs and impact on the HIV Response
As the war in Ukraine enters its fifth year, the humanitarian crisis continues to deepen, with profound consequences for access to essential services, including health care.
Modern warfare tactics, including the widespread use of drones and repeated attacks on critical infrastructure, are increasin
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g civilian harm and fundamentally reshaping how health services are delivered, especially in conflict-affected settings.
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Le document présente un cadre stratégique de l’Organisation mondiale de la Santé pour la gestion des risques liés aux situations d’urgence et aux catastrophes dans le domaine de la santé. Il met en évidence que ces événements (comme les épidémies, les catastrophes naturelles ou les con
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flits) ont des impacts majeurs sur la santé, les systèmes de soins et le développement des sociétés. Le cadre propose une approche globale et proactive fondée sur la prévention, la préparation, la réponse et le relèvement, tout en soulignant l’importance de la collaboration entre différents secteurs et acteurs. L’objectif principal est de réduire les risques sanitaires, de renforcer la résilience des communautés et des systèmes de santé, et d’améliorer la sécurité sanitaire à l’échelle mondiale.
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Artificial intelligence for tuberculosis control: a scoping review of applications in public health
Menon, S.; and K. Ghislein Kuro
(2025)
J Glob Health. 2025;15:04192. This scoping review highlights the potential of AI-driven predictions in national TB programmes to enhance diagnostics, track trends, and strengthen public health surveillance. While promising for reducing transmission and support-
ing TB care in low-resource settings,
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these models require large-scale validation to ensure real-world applicability, especially for high-risk groups
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Guía de manejo clínico del paciente grave con fiebre amarilla
recommended
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Las recomendaciones aquí presentadas fueron elaboradas a partir de una síntesis sistemática de la evidencia disponible y adoptan un enfoque pragmático, orientado a facilitar su aplicación en escenarios clínicos complejos y de alta demanda. Su desarrollo se fundamenta en los principios de la me
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todología GRADE, lo que garantiza transparencia en la evaluación de la evidencia y claridad en la formulación de las recomendaciones.
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International Journal for Parasitology: Drugs and Drug Resistance Volume 28, August 2025, 100602
This review provides innovative insights to circumvent antimalarial drug resistance and diversify malaria therapeutics.
