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The many faces of diabetes. Is there a need for re-classification? A narrative review
Sakran, N.; Graham, Yiitka.; Pintar, T.; et al.
BMC Endocrine Disorders Volume 22 Article Number 9
(2022)
CC
The alarming rise in the worldwide prevalence of obesity and associated type 2 diabetes mellitus (T2DM) have reached epidemic portions. Diabetes in its many forms and T2DM have different physiological backgrounds and are difficult to classify. Bariatric surgery (BS) is considered the most effective
...
treatment for obesity in terms of weight loss and comorbidity resolution, improves diabetes, and has been proven superior to medical management for the treatment of diabetes. The term metabolic surgery (MS) describes bariatric surgical procedures used primarily to treat T2DM and related metabolic conditions. MS is the most effective means of obtaining substantial and durable weight loss in individuals with obesity. Originally, BS was used as an alternative weight-loss therapy for patients with severe obesity, but clinical data revealed its metabolic benefits in patients with T2DM. MS is more effective than lifestyle or medical management in achieving glycaemic control, sustained weight loss, and reducing diabetes comorbidities. New guidelines for T2DM expand the use of MS to patients with a lower body mass index.
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What does the future hold for the world’s children?
In many ways, the future is now. Today’s actions and decisions will determine the future children inherit.
Unfortunately, today's children live in a world fraught with crises, poverty and discrimination. Where far too many are deprived of
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opportunities to meet their full potential.
We can and must do better.
The future of childhood hangs in the balance.
This year’s State of the World’s Children Report examines the forces and trends shaping our world today and reflects on how they might shape the future.
The report explores three megatrends that will profoundly impact children’s lives between now and 2050: demographics shifts, the climate and environmental crises and frontier technologies.
It also presents three future scenarios – possible outcomes, not predictions – for how children could experience the world of 2050.
As we consider what we can do today, our responsibility is clear: now is the time to shape a better future for every child.
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“All sectors of humanitarian response are critical to providing an adequate and holistic response for children who have survived different types of violence, exploitation, abuse and neglect. Following the immediate humanitarian response, all humanitarian sectors have an important contribution to m
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ake to the effective rehabilitation and reintegration of child survivors. ‘Mainstreaming’ child protection, or ensuring that child protection considerations inform all aspects of humanitarian action, helps to maximize the child protection impacts of the work that all humanitarians do. ”
How to Use This briefing paper: This briefing paper is a quick reference for Plan International Child Protection in Emergencies (CPiE) staff on how to engage with other sectors operating in the emergency to ensure that child protection principles and considerations inform all aspects of humanitarian programming in other sectors. While there is child protection mainstreaming guidance for how to work with specific sectors (e.g. WASH, nutrition, distribution) this “All Sectors” briefing note can give CPiE staff the big picture of shared child protection mainstreaming messages that should be conveyed to all sectors. This briefing is aligned with the Minimum Standards for Child Protection in Humanitarian Action and the Sphere Standards, as well as Plan International staff feedback on what actions are the most vital for child protection mainstreaming in other sectors.
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This two-site randomised trial compared the effectiveness of a voluntary sector-led, community-based diabetes prevention programme to a waiting-list control group at 6 months, and included an observational follow-up of the intervention arm to 12 months.
Les tendances démographiques d’aujourd’hui façonneront la répartition des populations de demain. Il en va de même pour le carbone que nous rejetons dans l’atmosphère aujourd’hui, qui déterminera le climat de demain ou pour les technologies que nous développons et gouvernons, qui influ
...
enceront non seulement la manière dont les futures générations apprendront, travailleront et communiqueront, mais aussi le bien-être des enfants au cours des années à venir.
Alors que le premier quart du XXIe siècle touche à sa fin, le rapport La Situation des enfants dans le monde 2024 nous projette en 2050 et tente de répondre à la question suivante : Quelle est la meilleure voie à suivre pour assurer un avenir dans lequel chaque enfant jouit de ses droits, et bâtir un monde dans lequel tous les enfants survivent, s’épanouissent et réalisent leur plein potentiel?
Pour ce faire, ce rapport examine trois grandes tendances, à savoir trois forces puissantes qui s’inscrivent dans la durée à l’échelle mondiale et qui auront de profondes répercussions sur la vie des enfants entre aujourd’hui et 2050 : les changements démographiques, la crise climatique et environnementale et les technologies d’avant-garde. Comprendre ces tendances et leurs implications pour les enfants semble en effet essentiel pour mieux appréhender les défis et les possibilités qui
nous attendent
more
Las tendencias demográficas actuales determinarán las futuras características de la población. El carbono expulsado hoy a la atmósfera definirá el clima del mañana. Las tecnologías que hoy desarrollamos y controlamos no solo influirán en la forma de aprender, trabajar y comunicar de las fut
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uras generaciones, sino también en el bienestar de la infancia durante las próximas décadas.
Conforme el primer cuarto del siglo XXI llega a su fin, el Estado Mundial de la Infancia 2024 ha decidido mirar hacia adelante y situarse en el año 2050. Y plantea la siguiente pregunta: ¿cuál es la mejor manera de lograr un futuro donde todos los niños y niñas disfruten de sus derechos? ¿Cómo podemos construir un mundo donde todos puedan sobrevivir, prosperar y desarrollar plenamente su potencial?
El informe examina tres megatendencias o grandes fenómenos mundiales y a largo plazo que tendrán importantes efectos sobre las vidas de los niños y niñas de aquí a 2050: los cambios demográficos, las crisis climáticas y medioambientales y las tecnologías de vanguardia. Si entendemos estas tendenciasy lo que implican para la infancia, comprenderemos mejor los retos y las oportunidades que se nos pueden presentar.
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ستشكل الاتجاهات الديموغرافية اليوم أنماط السكان في المستقبل. وسيحدد الكربون الذي نسكبه اليوم بغزارة في الغلاف الجوي معالم مناخ الغد. وستؤثر التقانات التي نطورها ون
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تحكم بها اليوم على طرق تعلم الأجيال المقبلة وعملها وتواصلها وأيضاً على عافية الأطفال لسنوات طويلة.
مع اقترابنا من نهاية الربع الأول من القرن الحادي والعشرين، يتطلع تقرير حالة أطفال العالم لعام 2024 إلى عام 2050. ويسأل: كيف يمكننا تأمين مستقبل تتحقق فيه حقوق جميع الأطفال — عالم يحيا فيه جميع الأطفال ويزدهرون ويحققون إمكاناتهم بالكامل؟
يتناول هذا التقرير ثلاث قوى عالمية قوية وطويلة الأمد (أو اتجاهات كبرى) ستترك أثراً عميقاً على حياة الأطفال من الآن حتى عام 2050، وهي: التحولات الديموغرافية، وأزمات المناخ والبيئة، والتقانات الرائدة. وبفهم هذه الاتجاهات وتداعياتها على الأطفال، يمكننا أن ندرك بشكل أفضل التحديات والفرص التي تنتظرنا.
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L’article « Traitement du paludisme d’importation de l’enfant » sur le site Pas à Pas en Pédiatrie traite de la prise en charge médicale du paludisme chez les enfants revenant de zones endémiques. Il décrit les différents types de paludisme, les symptômes à reconnaître, les critère
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s de gravité, ainsi que les traitements recommandés selon les formes cliniques et l’espèce de Plasmodium en cause. L’accent est mis sur l’importance du diagnostic rapide et de l’adaptation de la prise en charge aux recommandations françaises.
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STANDARD OPERATING PROCEDURES - PREVENTION AND CARE FOR CHILD SURVIVORS
Pregnant travelers face numerous risks, notably increased susceptibility to or severity of multiple infections, including malaria. Because pregnant women residing in areas non-endemic for malaria are unlikely to have protective immunity, travel to endemic areas poses risk of severe illness and pregn
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ancy complications, such as low birthweight and fetal loss. If travel to malaria-endemic areas cannot be avoided, preventive measures are critical. However, malaria chemoprophylaxis in pregnancy can be challenging, since commonly used regimens have varying levels of safety data and national guidelines differ. Furthermore, although chloroquine and mefloquine have wide acceptance for use in pregnancy, regional malaria resistance and non-pregnancy contraindications limit their use. Mosquito repellents, including N,N-diethyl-m-toluamide (DEET) and permethrin treatment of clothing, are considered safe in pregnancy and important to prevent malaria as well as other arthropod-borne infections such as Zika virus infection. Pregnant travelers at risk for malaria exposure should be advised to seek medical attention immediately if any symptoms of illness, particularly fever, develop.
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MOBILISIERUNG INLÄNDISCHER ÖFFENTLICHER RESSOURCEN FÜR GESUNDHEIT
Diese Publikation erklärt anhand von Grafiken die Wichtigkeit von Entwicklungszusammenarbeit im Allgemeinen und für Gesundheit im Speziellen. Denn finanzielle Beiträge im Rahmen der Entwicklungszusammenarbeit haben sich in den letzten Jahrzehnten als unerlässlich, wirksam, günstig und verantwor
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tungsvoll erwiesen.
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لى الرغم من أّن أفريقيا تحتضن ما يقارب خمس سكان العالم وتتحمل ربع العبء المرضي عالمًيا، فإن مساهمتها في الأبحاث
لا ةيملاعلا ةيحصلا زواجتت 3 طقف % . نمكي و دحأ زربأ ةي
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صلا ثاحبلأا هجاوت يتلا تايدحتلا يف ةراقلا يف تايقلاخأ راطإ فعض
ثحبلا روصقو يف ةيلودلا ثحبلا تايقلاخأ ئدابم لا ريفوت ةيامح يلثملا لل يف ةقرافلأا نيكراشم ةيثحبلا تاساردلا . زيمتت
بوعشلا ةيقيرفلأا ب دقتعم تاموظنمو ميقو تافاقث ية لئاضفو ةديرف ، يعدتسي امب لاا و فاشكتس لا مهف قمعب قايس يف
ريت في بيئة أفريقية بأن ضرمل ةيبلس تاصيخشتب ىضرملا غلابإ ُج أ ،لاثملا ليبس ىلع .ثحبلا تايقلاخأ جئاتن ترهظ دراسٌة أ
ءانثأناطرسلا دق ةرينتسملا ةقفاوملا ةيلمع يلعرثؤت .ىضرملل ةياعرلاو جلاعلا جئاتن بلا يف ،ةيقيرفلأا تائي فلاخب لودلا
،ةمدقتملا ُيمنح اهتمام أكبر لا عمتجملا ةيللاقتس باسح يلع .درفلا ةيللاقتسا كلذ يلع ةولاع فف ةيقيرفلأا تاعمتجملا ي
دق ،ظوحلم لكشب ةيحصلا ةفاقثلا تايوتسم اهيف ضفخنت يتلا دحي مهف ةعيبط ةقفاوملا ةرتف للاخ ضارملأاو ثاحبلأا
ةرينتسملا نم ةرينتسم تارارق ذاختا ىلع ةردقلا ةيفاك ةفرعم ىلع ةينبمو ةيعاو . ةيداصتقلااو ةيعامتجلاا عاضولأا يندت نأ ام
فلأا ناكسلل يف نيكراشملا ةقرا طاخملل ةضرع رثكأ مهلعجي دق تاساردلا ، إذ قد تؤثر الحوافز الُمقّدمة عليهم في قرارات مه
ب .اهيف ةكراشم
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Seulement 3 % de la recherche mondiale en santé provient d’Afrique, malgré sa part de 18 % de la population
mondiale et de 25 % de la charge de morbidité. L’un des défis auxquels est confrontée cette recherche limitée en
matière de santé sur le continent provient du cadre défaillant d
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e l’éthique de la recherche et de l’incapacité des
principes internationaux d’éthique de la recherche à protéger de manière optimale les participants africains à la
recherche. Les populations africaines possèdent des cultures, des valeurs, des systèmes de croyances et des
vertus spécifiques qu'il convient d'explorer et de comprendre pour mener la recherche de manière éthiques. Par
exemple, une étude menée en Afrique a révélé que l'information sur les diagnostics, notamment ceux de cancer,
lors du consentement éclairé a été jugée défavorable, ce qui peut altérer le traitement et les résultats des soins
prodigués aux patients. En Afrique, contrairement aux pays développés, l'accent est davantage mis sur
l'autonomie communautaire que sur l'autonomie individuelle. Le niveau d’alphabétisation en santé des populations
africaines est faible par rapport à celui des pays développés, ce qui affecte leur compréhension du consentement
éclairé et compromet leur capacité à prendre des décisions éclairées. Le statut socio-économique inférieur des
populations africaines pourrait également rendre les participants à l'étude vulnérables, car les incitations offertes
pourraient influencer leur décision de participer à l'étude.
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Dies ist ein entscheidender Moment bei der Bekämpfung von HIV, Tuberkulose (TB) und Malaria. Für unsere achte Wiederauffüllung benötigt der Globale Fonds 18 Milliarden US-Dollar, um 23 Millionen Menschenleben zu retten, die Sterberate der drei Krankheiten um 64 % zu senken und am Aufbau einer We
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lt mitzuwirken, die gesünder, sicherer und gerechter ist.
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Diese Veröffentlichung befasst sich mit der öffentlichen Entwicklungshilfe (Official Development Assistance, ODA) der USA mit Schwerpunkt auf den Bereichen Gesundheit, HIV/AIDS, Tuberkulose und Malaria. Außerdem wird die ODA der USA im Vergleich zu anderen Gebern und Finanzierungszielen betrachte
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t.
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Zero draft of the outcome document adopted at the Third Internatinal Conference on Financing for Development (Addis Ababa, Ethiopia, 13–16 July 2015) and endorsed by the General Assembly in its resolution 69/313 of 27 July 2015.
The UN’s SDG Stimulus Plan, which calls for additional liquidity, effective debt restructuring and the expansion of development financing, has the potential to free up significant fiscal space in developing economies. For 52 most debt-vulnerable economies, a 30 percent haircut of 2021 public exter
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nal debt stock could lower debt service payments in 2022–2029 by between US$44 billion and $148 billion, depending on the participation of various creditor classes. For all developing economies, a 40 percent “refinancing” of their 2021 bond debt stock to average official creditor rates could amount to a $121 billion savings on interest payments in 2022–2029. Against the backdrop of growing economic and geopolitical fragmentation, this policy brief describes building blocks for exiting the crisis.
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FACTI Panel Interim Report - Executive Summary
The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel)
The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel)
(2020)
CC
The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel) was convened by the 74th President of United Nations General Assembly and the 75th President of the Economic and Social Council on 2 March 2020. The objective of the
...
FACTI Panel is to contribute to the overall efforts undertaken by Member States to implement the ambitious and transformational vision of the 2030 Agenda for Sustainable Development. It is mandated to review current challenges and trends related to financial accountability, transparency and integrity, and to make evidence-based recommendations to close remaining gaps in the international system.
more
FACTI Panel Interim Report
The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel)
The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel)
(2020)
CC
The High-Level Panel on International Financial Accountability, Transparency and Integrity for Achieving the 2030 Agenda (FACTI Panel) was convened by the 74th President of United Nations General Assembly and the 75th President of the Economic and Social Council on 2 March 2020. The objective of the
...
FACTI Panel is to contribute to the overall efforts undertaken by Member States to implement the ambitious and transformational vision of the 2030 Agenda for Sustainable Development. It is mandated to review current challenges and trends related to financial accountability, transparency and integrity, and to make evidence-based recommendations to close remaining gaps in the international system.
more
