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Mindfulness meditation improves emotion regulation and reduces drug abuse

Tang, Y.Y.; Tang, R.; Posner, M.I. Drug and Alcohol Dependence (2016) CC
Background The core clinical symptoms of addiction include an enhanced incentive for drug taking (craving), impaired self-control (impulsivity and compulsivity), emotional dysregulation (negative mood) and increased stress reactivity. Symptoms related to impaired self-control involve reduced activi... more
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Relaxation training

World Health Organization WHO (2012) C_WHO
The number of general health staff skilled in psychological treatment for depression is limited, and learning psychological treatments tends to require considerable training and supervision. Relaxation may be a relatively simple form of psychological treatment. It has been frequently studied in rese... more
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Substance abuse treatmentand care for women: Case studies and lessons learned

United Nations Office on Drugs and Crime (UNODC) (2004) C1
The present booklet is about gender-responsive substance abuse treatment services for women. It is part of the United Nations Office on Drugs and Crime (UNODC) project to develop tools to support the development and improvement of substance abuse treatment services, based on evidence from the litera... more
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Physical activity. Mental Health GAP resources.

World Health Organization WHO (2012) C_WHO
Advice on physical activity should be encouraged as part of treatment for adults with depressive episode/disorder with inactive lifestyles. In moderate and severe depression, this intervention should be considered as adjunct to antidepressants or brief structured psychological treatments.
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Gaps in service Utilization and service provision: an analysis of DHS and SPA Malaria data from Malawi, Senegal, and Tanzania

C. Taylor, A. Linn, W. Wang, and H. Moussa (2018) C2
Barriers to the prompt and effective diagnosis and treatment of malaria exist at both the community and health facility level. Household surveys measure malaria case management at the population level with standard indicators that assess treatment-seeking behavior, access to diagnostic testing, and ... more
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Dementia mhGAP module
recommended

World Health Organization WHO (2017) C_WHO
DEM supporting material • Person stories • Role plays • Case scenarios • Treatment planning handouts • Treatment planning suggestions • Multiple choice questions • Video link Activity 3: mhGAP DEM module – assessment
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Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy

Tirados, I.; Esterhuizen, J.; Kovacic, V.; Mangwiro, TNC.; Vale, GA et al. PLOS Neglected Tropical Diseases (2015) CC
Sleeping sickness is controlled by case detection and treatment but this often only reaches less than 75% of the population. Vector control is capable of completely interrupting HAT transmission but is not used because of expense. We conducted a full scale field trial of a refined vector control tec... more
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Human African Trypanosomiasis (HAT) - Sleeping Sickness

Drugs for Neglected Diseases initiative DNDi (2008) C2
At the forefront of DNDi’s efforts to develop new treatments is the need to understand the realities and treatment needs of patients and health care staff in the field. The ultimate goal for human African trypanosomiasis (HAT) is a truly simplified treatment which can be orally administered, impl... more
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Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership.

Bernhard, S.; Kaiser, M.; Burri, C.; Mäser, P. Diseases (2022) CC
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery for HAT with special emphasis on the discovery, pre-clinical development, and operational challenge... more
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The Chagas disease study landscape

Maguire, B.; Dahal, P.; Rashan, S. et al. PLoS Neglected Tropical Diseases (2021) CC
A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations s... more
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Social Anxiety Disorder

National Institute for Health and Care Excellence (NICE) (2013) C2
Recognition, Assessment and Treatment National Clinical Guideline Number 159
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Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions

Phillips, O.; J. Robert, K. Mohamed Abass et al. The Lancet Journal (2020) CC
The Lancet olume 395, ISSUE 10232, P1259-1267, April 18, 2020. Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia. Standard antimicrobial treatment with oral rifa... more
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Buruli ulcer: cured by 8 weeks of oral antibiotics?

Johnson, P.D.R. The Lancet Journal (2020) C1
Phillips and colleagues have shown that rifampicin combined with clarithromycin is non-inferior to RS8, and is safer. This much anticipated trial provides us with a high degree of confidence that an 8-week course of oral rifampicin and clarithromycin should now be the cornerstone of the treatment of... more
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MSF الإرشادات السريرية. دليل التشخيص والعلاج
recommended

Médecins sans Frontières (MSF) (2022) C2
Clinical Guidelines. Diagnosis and Treatment Manual.
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Antimicrobial Resistance Resource Platform
recommended

World Health Organization WHO (2022) C_WHO
Antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. AMR occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections ha... more
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HIV drug resistance report 2021

World Health Organization (WHO) (2021) C_WHO
The HIV drug resistance report 2021 summarizes findings from 38 countries that had finalized the surveys by the time of this report and shared data with WHO. Pretreatment HIVDR to non-nucleoside reverse-transcriptase inhibitors (NNRTI) can affect more than 10% of adults starting therapy and is fo... more
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UNAIDS data-2021

UNAIDS (2021) C_CDC
Global and Regional Data 1 December 2021; The 90–90–90 targets were missed, but not by much. At the end of 2020, 84% of people living with HIV knew their HIV status, 87% of people living with HIV who knew their HIV status were accessing antiretroviral therapy, and 90% of people on treatment were... more
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WHO Sciene in 5 Episode #33 - Medical oxygen

World Health Organization WHO (2021) C_WHO
Medical oxygen is an essential medicine in the treatment of COVID-19. How is it used? Why is there a shortage in some countries and what are WHO, partners and Governments doing about it? WHO’s Dr Janet Diaz explains in Science in 5.
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Statement on the Use of Ivermectin for COVID-19

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1
Ivermectin is an antiparasitic drug approved for the treatment of parasitic infections, including strongyloidiasis and onchocerciasis in humans. There is a reported increase in the use of ivermectin for the prevention and treatment of COVID-19 by the public in African Union Member States. Currently... more
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Covid-19 AMBOSS. English

AMBOSS (2020) CC
The outbreak of the coronavirus is leading to increased challenges in clinical management and uncertainty among the general population. To support the advice and treatment of patients, we have updated our Knowledge Library to include an informative Learning Card about COVID-19. This update contai... more