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These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
The goal of producing these Standard Operating Procedures (SOPs) was therefore targeted at fostering standardization across all levels of care to ensure HIV viral load monitoring remains a basic right offered to all people living with HIV (PLHIV) on lifelong antiretroviral therapy (ART) regardless o ... more
About six in ten adolescents 10-19 years of age living with HIV are on antiretroviral medications
Slightly more than half of children under 15 years of age living with HIV are on antiretroviral medications
The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations. The guidelines were updated to comply with Executive Orders. You can download the full guidelines, charts and recommendations
JAMA. 2025;333(7):609–628. doi:10.1001/jama.2024.24543
Lancet HIV 2019 Published Online March 15, 2019 http://dx.doi.org/10.1016/S2352-3018(19)30052-9 Analytical antiretroviral treatment interruption (ATI) is an important feature of HIV research, seeking to achieve sustained viral suppression in the absence of antiretroviral therapy (ART) when the goa ... more
Nature communications, 16, 906 (2025). https://doi.org/10.1038/s41467-025-56116-1
Recent suspensions and reductions in official development assistance (ODA) have posed significant challenges to HIV programme continuity in several countries. These funding disruptions have impacted people living with HIV and other vulnerable populations who rely on these essential services, like a ... more
Dosing of LPV/r by formulation & dose modification (RTV super-boosting/double-dose LPV/r) for children receiving rifampicin-containing TB treatment. Chart
What is new in this guideline. Fact Sheet
Annexure 6 National Guidelines South Africa 2023
The emergence of high-level dolutegravir resistance was extremely rare in people switched to first-line dolutegravir-based treatment in Zambia and Malawi, a large prospective study has found.
Modelling shows that it will be essential to complement lenacapavir with additional prevention options, testing and treatment. See “Meeting reports” at https://www.unaids.org/en/resources/publications/all for a description of models and tools to estimate potential impact and quantifications requ ... more
In line with the Defeating meningitis by 2030: a global road map, the WHO guidelines on meningitis diagnosis, treatment and care Executive Summary provides a summary of the evidence-based recommendations for the clinical management of children and adults with community-acquired meningitis, including ... more
El documento es una guía de bolsillo para establecer y operar un Centro de Tratamiento de Cólera (CTC). Proporciona pautas para seleccionar la ubicación, clasificar a los pacientes según la gravedad de la deshidratación, implementar medidas de control de infecciones y garantizar el suministro a ... more
The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping laboratory services producing comparable and reliable ... more

Guideline: Adherence to antiretroviral therapy in adolescents and young adults (expanded version)

L. Fairlie; L. Jankelowitz; H. Ronald; et al. Southern African HIV Clinicians Society; Right to Care (Training Health Seriously) (2017) C2
Recommendations, resources and references A publication of the Southern African HIV Clinicians Society
The target audience for this training course is non-clinicians such as Home Based Carers, Community Caregivers, Youth Care Workers, Peer educators, Community Health Workers etc. primarily those who will be providing adherence counselling to clients with HIV, TB, Hypertension and Diabetes. This group ... more
PARTICIPANT GUIDE. This Participant Guide has been designed to assist health facilities and community based non-clinicians to develop skills to provide linkage to care, adherence and retention in care services for chronic conditions