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This guideline is intended to provide recommendations to applicants wishing to submit applications for the registration of medicines. It represents the Medicines Control Council’s current thinking on the safety,
...
quality and efficacy of medicines.
more
The standards of care for HIV define the expected or desired quality of prevention, treatment, and care for people at risk of HIV acquisition or living with HIV.
The standards are based on a scientific rationale, as well as the responsibilities of
...
each stakeholder, to ensure that people receive appropriate, high-quality prevention and care that aligns with the most up-to-date medical knowledge and ethical standards
more
Mpox Molecular Diagnostic Tests(RT-PCR)
recommended
March 2025. Access to appropriate, quality-assured diagnostics remains a challenge. There is limited information on key characteristics of available test kits, including their performance, reliability, and ability to detect relevant Mpox clades. Add
...
itionally, the lack of multiplex diagnostic tools capable of distinguishing Mpox from other pathogens with similar clinical presentations further complicates case detection and response efforts.
more
The Pocket Guide to Managing Contraceptive Supplies addresses one of
the most important components of any program that provides family
planning services—the logistics system that manages the delivery,
quality, and storage of contraceptive suppl
...
ies. These supplies are
essential; without them, family planning services cannot be provided.
This guide is for the staff of family planning or health clinics who
manage contraceptive supplies and for the supervisor who oversees
these logistics activities. This booklet is not a complete logistics text;
its purpose is to be a quick reference for logistics formulas and
principles to help you manage your supplies (both contraceptives and
other commodities) correctly and efficiently.
more
Veterinarians are leaders and stewards in preserving the effectiveness of antibiotics for animals and people. Working with animal owners and producers, veterinarians can slow antibiotic resistance by implementing disease prevention strategies and improving the use of antibiotics while also guarante
...
eing high-quality medical care for animal patients.
more
This Cardiac Rehabilitation Change Package was completed by the Centers for Disease Control and Prevention (CDC) in collaboration with the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) with the purpose of helping cardi
...
ac rehabilitation programs, hospital quality improvement teams, and public health professionals who partner with these groups to implement systems and strategies that improve care for patients who are eligible for cardiac rehabilitation. AACVPR is a multidisciplinary professional association comprised of health professionals who serve in the field of cardiac and pulmonary rehabilitation.
more
A key component of elimination is to reduce the number
of unmanaged trachomatous trichiasis cases to less than
1 per 1,000 population in affected areas. This will require
not only a large increase in the number of surgeries
performed, but also improvements in the
...
quality of surgery
and in the efficiency of surgery provision programs. It also
will require that we make special efforts to reach out to
women and the most marginalized populations, who are
disproportionally affected by trichiasis (TT).
more
A crucial element in accelerating progress is the development of improved surveillance systems and tools that provide decision-makers with timely, high-quality data and actionable insights. The investments made to establish genomic platforms for COV
...
ID-19 surveillance have catalyzed a genomic revolution—one that can now be leveraged to strengthen the surveillance of endemic diseases such as malaria.
more
The document provides a standardized protocol for evaluating the Early Warning Alert and Response Network (EWARN), a surveillance system used during humanitarian emergencies when regular national health surveillance may be disrupted. The purpose of EWARN is to detect outbreaks of communicable diseas
...
es early and enable rapid public health response. The guidance explains how the system should be assessed in terms of its structure, implementation, effectiveness, and usefulness. It outlines the key steps of evaluation: preparation, system description, data collection, and post-evaluation reporting. The protocol highlights common challenges observed in previous EWARN implementations, such as delays in establishing the system, limited data quality, weak outbreak response, and lack of clear transition plans back to routine surveillance systems. It emphasizes the need to evaluate both weekly disease reporting and alert verification processes, and to review attributes such as simplicity, data quality, timeliness, sensitivity, and stability. The document also provides templates for interviews, data review forms, and laboratory assessment, as well as guidance on conducting remote evaluations when access is limited. The overall goal of the protocol is to ensure that EWARN functions effectively to detect and respond to outbreaks and that practical recommendations are developed to improve the system’s performance and sustainability in emergency settings.
more
The importance of robust mortality surveillance systems cannot be overstated in an era marked by increasing global health challenges where health threats loom large and population dynamics continue to evolve. Accurate and timely mortality data is essential for identifying trends and detecting emergi
...
ng health threats, evaluating the impact of interventions, and guiding evidence-based policy decisions.
This framework outlines a holistic approach to strengthening routine mortality surveillance systems, considering the unique contextual factors and challenges faced by African countries. It emphasizes the importance of establishing efficient data collection mechanisms, enhancing data quality and completeness, and promoting data sharing and collaboration among stakeholders.
Moreover, the framework recognizes the pivotal role of technology in the integration of data from fragmented mortality data sources. It highlights the potential of innovative data capture methods, advanced analytics, and real-time reporting systems to enhance mortality data’s accuracy, efficiency, and timeliness.
The continental framework for mortality surveillance aligns with Africa CDC’s mission and strategic goal by serving as a fundamental component in strengthening public health systems, enhancing disease surveillance capacities and capabilities, informing evidence-based policies and interventions, and promoting collaboration and coordination among African countries to address health challenges and improve health outcomes on the continent.
The successful implementation of this framework requires collective commitment and concerted efforts from governments, health institutions, and the international community. We hope this document will serve as a catalyst for transformative change, enabling countries to build resilient mortality surveillance systems that protect public health, save lives, and contribute to evidence-based decision-making.
more
This document assembles these best practices and provides a resource for the proper management of equipment in the laboratory to ensure accurate, reliable and timely testing, and maintain a high level of laboratory performance. Improved equipment management also lowers repair costs, lengthens instru
...
ment life, reduces interruption of services due to breakdowns and failures, and enables laboratory accreditation and the achievement of high-quality and accessible laboratory services at all levels of healthcare service delivery.
more
The National Guidelines for HIV-1 Viral Load Laboratory Testing support plans to scale up viral load (VL) testing to reach the 90-90-90 targets in India. This phased scale-up includes the setup of 70 additional VL testing laboratories nationally. These guidelines include laboratory design considerat
...
ions, a summary of VL technologies, and specimen collection and handling as well as transportation and storage guidance. Quality control and quality assurance requirements are described as well as laboratory safety issues. The guidelines also describe the VL laboratory network to be developed with supply chain management issues and commodities described. Annexes include laboratory registers and reporting forms.
more
Tutorial of local production of alcohol-based solution (WHO formulation)
WHO Collaborating Centre of Patient Safety Infection Control & Improving Practices; Hôpitaux Universitaires de Genève (HUG); Pharm-Ed
WHO Collaborating Centre of Patient Safety Infection Control & Improving Practices; Hôpitaux Universitaires de Genève (HUG); Pharm-Ed
(2016)
C2
14.04.2016
Pharm -Ed
--
The alcohol-based solution for hand hygiene is now part of the WHO essential medicines list .Local production of the alcohol-based handrub is an alternative to commercial products. Although adapted to contexts with limited resources, it is essential to respect the Good Man
...
ufacturing Practices to ensure the quality, efficacy and safety of the product.
If you need production sheet, checklist of the material needed etc., please click on the following link: https://pharmed.datapharma.ch/courses...
Pharm-Ed (www.Pharm-Ed.net) is an initiative of the Pharmacy of the Geneva University Hospitals in Switzerland. The platform is free but registration (for free) is needed to access the e-learning courses and resources.
more
ASLM in collaboration with the Africa Centres for Disease Control and Prevention, and in partnership with the Clinton Health Access Initiative, Amref and Last Mile Health present the Quality Assuran
...
ce Framework for SARS-CoV-2 Antigen Rapid Testing for Diagnosis of COVID-19. This framework aims to provide general technical guidance to African Union Members States on the rollout, establishment, implementation, monitoring, and evaluation of SARS-CoV-2 Ag RDT interventions so as to effectively and efficiently detect, control and minimise errors in the performance of COVID-19 laboratory testing processes. It describes the core components for quality assurance, resources mobilisation and advocacy for scale up, monitoring, evaluation, learning and accountability for SARS-CoV-2 implementation.
more
The document “Guidelines for Writing Outbreak Investigation Reports” by the European Centre for Disease Prevention and Control provides practical guidance on how to prepare clear, structured, and scientifically sound reports after investigating
...
a disease outbreak. It is mainly intended for epidemiologists and public health professionals, particularly participants in the ECDC Fellowship Programme. The guide explains the purpose of outbreak investigation reports and describes the recommended structure and content of such reports, including sections such as background, objectives, methods, results, and conclusions. It also outlines how to present epidemiological, laboratory, and environmental findings, interpret the results, and formulate public health recommendations. Overall, the document aims to standardize outbreak reporting, improve the quality and clarity of reports, and ensure that investigation findings can effectively support public health decision-making and future outbreak prevention.
more
This guidance addresses rationale, risk-based scenarios, practical considerations prior to adoption of the self-testing products, quality assurance, safety and ethical considerations, and data management considerations for COVID-19 self-testing. The
...
Africa CDC recommends the use of rapid antigen self-testing within two key scenarios. The first includes testing for case identification within scenarios with a high risk of infection, including symptomatic cases and contacts of a confirmed case. The second scenario involves general screening within scenarios of low or unknown risk exposure allowing for self-care such as before gatherings with at-risk individuals and prior to participation in events involving members of different households. Within these scenarios, a positive test result indicates likelihood of current infection, while a negative test result indicates a lower risk of active infection, though it does not rule out infection altogether. All positive cases should be managed following the national COVID-19 management protocol of Member States.ssur
more
27 May 2021
This is a document to support the use of pulse oximeter for assessment of suspected and confirmed cases of Covid-19 in the community.
It is a well-known fact that Covid-19 can present as “happy hypoxia” with minimum symptoms of severe respiratory distress despite significant low ox
...
ygen levels in the blood. The use of pulse oximeter for clinical assessment significantly augments decision making, save lives and provide high quality care. It allows for early detection of patients with hypoxia requiring either close monitoring in the community or timely referral for hospital care.
more
Through the USAID-funded Organized Network of Services for Everyone’s Health (ONSE) Activity, MSH is assisting Malawi’s National Malaria Control Program to provide high-quality malaria services
...
at the facility and community levels in 10 districts, covering nearly a third of the country.
Our team in Malawi share recent results on strengthening malaria services through Outreach Training and Supportive Supervision (OTSS).
Designed to provide ongoing support to clinicians, data, and laboratory staff, OTSS combines a standardized checklist with targeted mentorship and supportive supervision to identify areas for improvement and strengthen clinical and diagnostic services in health facilities.
This webinar shares lessons learned on how the application of OTSS, as part of broader quality assurance systems, impacts staff performance and improves the provision and quality of malaria services.
more
The manufacturing process is one of the key steps where quality control is required to ensure quality of medicinal products, including herbal medic
...
ines. Good manufacturing practices (GMP) is one of the most important tools for this measure.
more
Decontamination of medical devices plays an important role in the prevention of health care-associated infections. It includes cleaning, disinfection and/or sterilization. The processes involved in decontamination are complex, require specific infrastructure and equipment, and involve several sequen
...
tial steps that need to be performed correctly – from device collection and receipt by the decontamination unit to processing, storage and distribution throughout the facility. Quality control procedures (such as validation) at each step of the decontamination process are of the utmost importance to ensure the correct functioning of the equipment and processes. This aide-memoire presents a concise overview of important advice and key elements at a glance.
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