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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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DHR-ICMR GUIDELINES FOR DIAGNOSIS AND MANAGEMENT OF RICKETTSIAL DISEASES IN INDIA

Indian Council of Medical Research (ICMR) (2015) C1

The present DHR-ICMR guidelines comprehensively address the various concerns regarding the clinical assessment, treatment, and laboratory diagnosis of rickettsial diseases in India and the world. It is hoped that physicians, health care workers, the scientific community, the regulatory agencies, pub... more

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Senegal: Countdown to 2015 - Maternal, Newborn & Child Survival

Countdown to 2030 Commission (2015) C2

The Countdown country profile presents in one place the best and latest evidence to enable an assessment of a country’s progress in improving reproductive, maternal, newborn, and child health (RMNCH)

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Uganda: A Decade of Tracking Progress for Maternal, Newborn and Child Survival

Countdown to 2015 UNICEF; WHO (2015) C_WHO

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India: Nutrition Guidelines for HIV-Exposed and Infected Children (0-14 Years of Age)

Department of Aids Control, NACO, Ministry of Health and Family Welfare, Government of India (2013) C1

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Humanitarian Action for Children 2022 - Kenya

UN Children's Fund UNICEF (2021) C_UNICEF

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All abaout Rabies

Department of Health and Environmental Control (2022) CC

Rabies is a virus (Lyssavirus) that infects cells in the central nervous system, causing disease in the brain and, ultimately, death. Any animal with rabies has the ability to transmit the disease to humans or other animals. There is no cure for rabies, but it is 100 percent preventable through ... more

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Hospital-based birth defects surveillance: facilitator guide

World Health Organization ( WHO), Regional Oﬃce for South-East-Asia (2016) C_WHO

Birth defect has been an emerging major cause of child mortality in the region. Scarcity of the birth defects information hampers policy decisions and control measures at national level. In order to create evidence for action for birth defects prevention in the region, WHO-SEARO in collaboration wit... more

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Kenya: Fulfilling the Health Agenda for Women and Children

Countdown to 2015 (2015) C1

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Prevention and Control of Non-Communicable Diseases in Zambia: The Case for Investment

Ministry of Health, Zambia (2020) CC

The Government of the Republic of Zambia has placed priority on ensuring that Zambians are healthy and productive as a catalyst to the attainment of socioeconomic development . The Vision 2030 aims to transform Zambia into a prosperous middle-income country as articulated also in the 7th National De... more

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Network of WHO Collaborating centres for trachoma

World Health Organization World Health Organization WHO (2016) C_WHO

SECOND MEETING REPORT DECATUR, GA, USA, 26 JUNE 2016

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Target product profile for a test for rhodesiense human African trypanosomiasis diagnosis usable in peripheral health facilities

World Health Organization World Health Organization WHO (2021) C_WHO

The development of this target product profile (TPP) was led by the WHO Department of Control of Ne- glected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was... more

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Diagnostic methods for the control of strongyloidiasis, Virtual meeting, 29 September 2020

World Health Organization WHO (2021) C_WHO

23 March 2021 The meeting addressed the last key area, that is, determining the best method or combination of diagnostic methods for a control programme for S. stercoralis infections in humans. Dr Montresor’s presentation highlighted that while there is currently no “gold standard” for the... more

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Guidelines on the definition and characterization of extreme weather and climate events

Ren, F.; Pattanaik, D.; Cerveny, R. et al. World Meteorological Organization WMO (2023) CC

The guidance in this publication consists of generic definitions and methodologies for the characterization of extreme weather and climate events. This publication contribute to ensuring consistent exchange of information that underpins the WMO State of the Climate Reports, Climate Watches, climate ... more

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Progress Toward Global Eradication of Dracunculiasis

Hopkins, D.; Weiss, A.; Roy, S. Morbidity and Mortality Weekly Report MMWR; National Libary of Medicine (2020) CC

Dracunculiasis (Guinea worm disease), caused by the parasite Dracunculus medinensis, is traditionally acquired by drinking water containing copepods (water fleas) infected with D. medinensis larvae, but in recent years also appears increasingly to be transmitted by eating fish or other aquatic anima... more

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Advice for Humanitarian Aid Workers Traveling to Guinea, Liberia, Nigeria, or Sierra Leone during the Ebola Outbreak

Centers of Disease Control CDC (2014)

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The people living with HIV stigma index

N. Amanzholov; A. Yakovleva; D. Kamaldinov Central Asian Association of People Living with HIV (2019) C2

Analytical Report Almaty 2015 Accessed: 26.09.2019

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Clinical Management of Acute Diarrhoea

World Health Organization; UNICEF (2004) C_WHO

Available in Englisch, French, Spanish and Chinese The document provides guidelines for the management of acute diarrhoea, highlighting improved oral rehydration solutions (ORS) with reduced osmolarity and zinc supplementation. It emphasizes their effectiveness in reducing the duration and severity... more

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When you just can’t forget - Information about Post-Traumatic Stress Disorder

Schweizerisches Rotes Kreuz (2014) C1

This brochure is designed to help people who have experienced traumatic events and their families. Available in 10 languages: albanian, arabic, german, french, english, serbian/bosnian/croatian, farsi, tamil, tigrinya, turkish. For other versions check: https://www.redcross.ch/de/shop/gesundheit-... more

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Rwanda Demographic and Health Survey 2014- 15, District Profile Chart Book, City of Kigali.

National Institute of Statistics of Rwanda (NISR) [Rwanda], Ministry of Health (MOH) [Rwanda], and ICF International. (2015) C2

The National Institute of statistics of Rwanda (NISR) in collaboration with the worldwide Demographic and Health Surveys Program implemented the 2014-15 Rwanda Demographic and Health Survey (RDHS) to collect data for monitoring progress on health programs and policies in Rwanda. This publication ill... more