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Publication Years
2143
3933
636
41
3
1
Category
2468
689
353
307
273
172
102
2
Toolboxes
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528
524
399
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338
254
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87
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58
41
36
35
34
33
31
1
1
This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
The document provides a standardized protocol for evaluating the Early Warning Alert and Response Network (EWARN), a surveillance system used during humanitarian emergencies when regular national health surveillance may be disrupted. The purpose of EWARN is to detect outbreaks of communicable diseas
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es early and enable rapid public health response. The guidance explains how the system should be assessed in terms of its structure, implementation, effectiveness, and usefulness. It outlines the key steps of evaluation: preparation, system description, data collection, and post-evaluation reporting. The protocol highlights common challenges observed in previous EWARN implementations, such as delays in establishing the system, limited data quality, weak outbreak response, and lack of clear transition plans back to routine surveillance systems. It emphasizes the need to evaluate both weekly disease reporting and alert verification processes, and to review attributes such as simplicity, data quality, timeliness, sensitivity, and stability. The document also provides templates for interviews, data review forms, and laboratory assessment, as well as guidance on conducting remote evaluations when access is limited. The overall goal of the protocol is to ensure that EWARN functions effectively to detect and respond to outbreaks and that practical recommendations are developed to improve the system’s performance and sustainability in emergency settings.
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These guidelines update earlier WHO recommendations to maximize the HIV prevention impact of safe VMMC services and aim to guide the transition to the sustained provision of interventions with a focus on the health and well-being of both adolescent boys and men.
Topics in Antiviral Medicine, March 4, 2025
WHO updated recommendations on HIV clinical management: recommendations for a public health approach
recommended
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to
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support global initiatives aimed at ending AIDS as a public health threat by 2030. Key changes include the introduction of new antiretroviral drugs and regimens, revised postnatal prophylaxis and breastfeeding guidelines for managing infants at risk of vertical transmission, and the endorsement of shorter tuberculosis preventive treatments to improve efficacy and adherence.
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HIV rapid diagnostic test market landscape
recommended
The analysis includes the three most commonly used HIV rapid diagnostic test
(RDT) categories: HIV-only professional use RDTs, dual HIV/syphilis professional use
RDTs, and HIV self-tests (HIVST).
Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
ClinicalInfo.gov
(2025)
C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
Dosing Recommendations for Prevention and Treatment
Archives of Medicine vo.7 no.5:10
Individuals infected with human immunodeficiency virus (HIV) often develop
multiple complications and comorbidities, among them, opportunistic infections.
The highest incidence of opportunistic infections was reported in the group
of patients with CD4 lymphocyte
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levels below 200 cells / mm. Candidiasis,
toxoplasmosis and pneumocystis pneumonia (PCP) were the main representatives.
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Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV K-19 Tuberculosis/HIV Coinfection
Updated: September 12, 2024 Key Considerations and Recommendations
Recent suspensions and reductions in official development assistance (ODA) have posed significant challenges to HIV programme continuity in several countries. These funding disruptions have impacted people living with HIV and other vulnerable populations
who rely on these essential services, like a
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ntiretroviral treatment, particularly in settings reliant on external financing . In some cases, governments are stepping in to reestablish services that were previously provided through other sources of funding.
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The comic follows the story of Tiwale, a young girl from Malawi with dreams of becoming a football player. As she discovers that she is living with HIV, she learns to overcome her challenges with the support of her family and friends. This project investigates how the comic book is received by young
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people with HIV in Malawi and its effectiveness in improving their attitudes and behavior, with hopes of reaching more young people with similar concerns of living with HIV.
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The paper “Artificial Intelligence for Public Health Surveillance in Africa: Applications and Opportunities” examines how artificial intelligence (AI) can improve public health systems across Africa, particularly in low-resource settings. It explores how machine learning and other AI techniques
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are being used for disease detection, outbreak prediction, real-time surveillance, and health resource management.
The authors focus on major public health challenges such as HIV, cholera, Ebola, measles, tuberculosis, malaria, COVID-19, and mental health. Through numerous case studies, the paper shows that AI can enhance the accuracy and speed of disease detection, predict outbreaks more effectively than traditional methods, support vaccination strategies, and optimize healthcare resource allocation. At the same time, it discusses important barriers to implementation, including limited data quality, infrastructure constraints, ethical concerns, and shortages of technical expertise.
Overall, the paper highlights AI’s strong potential to strengthen disease surveillance and health outcomes in Africa while emphasizing the need for careful integration, improved data systems, and supportive policy frameworks.
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This Mobile user guidance is aimed at supporting implementation of EWARS in a box, WHO’s electronic early warning, alert and response system in emergencies. This guidance fulfills a long felt need to have an easy to use resource with step-by-step instructions in establishing EWARS in a box, facili
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tating field epidemiologists, surveillance officers and emergency responders.
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The document “Guidelines for the Investigation and Control of Disease Outbreaks” provides practical guidance for public health professionals on how to detect, investigate, and manage outbreaks of communicable diseases. It describes the key steps of outbreak investigation, including confirming th
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e outbreak, establishing a case definition, collecting epidemiological and laboratory data, identifying the source and mode of transmission, and implementing control measures. The guidelines also explain how to organize outbreak response teams, communicate findings, and document results in outbreak reports. Overall, the document aims to support systematic and effective outbreak investigations in order to control disease spread and protect public health.
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Outbreak Investigation, Response and Control – Module 8. Integrated Disease Surveillance Project: Training Manual for State & District Surveillance Officers
Integrated Disease Surveillance Project (IDSP)
Ministry of Health and Family Welfare, Government of India
(2005)
C2
The document “Outbreak Investigation, Response and Control – Module 8” is a training module from the Integrated Disease Surveillance Project (IDSP) designed to guide health officials in investigating and managing disease outbreaks. It explains the basic principles and steps of outbreak investi
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gation, including detecting unusual increases in disease cases, confirming diagnoses, collecting and analyzing epidemiological data, and identifying the source and mode of transmission. The module also describes appropriate control and prevention measures, emphasizes timely reporting and coordination within the surveillance system, and aims to strengthen the capacity of public health workers to effectively respond to infectious disease outbreaks at the district and state levels.
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The NIAID Pandemic Preparedness Plan describes the strategy of the National Institute of Allergy and Infectious Diseases (NIAID) to strengthen research and development for future pandemic threats. The plan focuses on identifying and studying viruses with the potential to cause epidemics or pandemics
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and developing medical countermeasures such as vaccines, therapeutics and diagnostics. A key concept is the research on “prototype pathogens,” which represent virus families that may cause future outbreaks, allowing scientists to prepare tools and knowledge in advance. The document also outlines the importance of surveillance, epidemiological research, technological innovation, clinical trials and international collaboration to enable a faster and more effective response to emerging infectious diseases. Overall, the plan aims to improve scientific preparedness so that new health threats can be detected earlier and controlled more rapidly.
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Le présent document a été publié pour la première fois en 2006 (Lewis et de Bernis, 2006). Il est vraiment remarquable de le lire aujourd’hui1 et de constater à quel point la situation de la fistule a changé. En 2006, ce travail original et novateur a mis en évidence la fistule obstétrica
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le en tant que problème urgent de santé publique et a permis d’élaborer les premiers conseils pratiques pour les personnes impliquées dans les soins aux femmes souffrant de cette affection. En 2018, la communauté internationale a appelé à l’élimination de la fistule obstétricale dans un délai de dix ans, s’inscrivant ainsi en droite ligne avec l’Agenda 2030 pour le développement durable et ses 17 objectifs mondiaux.
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