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How are vaccines developed?

World Health Organization WHO (2021) C_WHO
This article is part two in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. This article focuses on the ingredients in a vaccine and the three clinical trial phases. Part three outlines the nex... more
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The ACT-Accelerator: Two years of impact

World Health Organization WHO (2022) C_WHO
The two-year impact report for the Access to COVID-19 Tools (ACT) Accelerator details impact, case studies and timelines of key milestones for the Diagnostics, Therapeutics and Vaccines pillars, as well as the Health Systems and Response Connector.
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WHO’s Science in 5 Episode #70 - Upcoming new vaccines

World Health Organization WHO (2022) C_WHO
29 April 2022 What are the new vaccines in the pipeline? What are the challenges to turning vaccines into vaccination ? What timelines can we expect for future vaccines? WHO’s Dr Katherine O’Brien explains in Science in 5.
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Target Regimen Profiles for TB Treatment

World Health Organization WHO (2016) C_WHO
There is an urgent need for safer, simpler, more efficacious and accessible treatment regimens for all forms of TB. The development of Target Product Profiles for TB treatment regimens (referred to as Target Regimen Profiles or TRPs) seeks to guide the drug development process towards important regi... more
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WHO Science in 5 Episode #78 - mRNA technologies

World Health Organization WHO World Health Organization WHO (2022) C_WHO
mRNA technologies. What is their future and scope, and what are the challenges that countries might face in rolling them out? Hello and welcome to Science in5. I'm Vismita Gupta-Smith. We are talking to Dr.Soumya Swaminathan today. Soumya, talk to us about mRNA technologies. What is the future?
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The COVAX facility

World Health Organization WHO (2020) C_WHO
Global procurement for COVID-19 vaccines
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How do vaccines work?

World Health Organization WHO (2021) C_WHO
This article is part four in a series of explainers on vaccine development and distribution Available in different languages
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2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline
recommended

World Health Organization WHO (2019) C_WHO
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions. Gr... more
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Vaccine efficacy, effectiveness and protection

World Health Organization WHO (2021) C_WHO
14 July 2021 This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and equitable access – in WHO’s Vaccines Explained series. COVID-19 vaccines have proven to be safe, ... more
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Newborn survival in Nepal: a decade of change and future implications

Pradhan, Y.V., Upreti, S.R., Pratap, K.C.N, et al. Health Policy and Planning (2012) CC
Nepal is on target to meet the Millennium Development Goals for maternal and child health despite high levels of poverty, poor infrastructure, difficult terrain and recent conflict. Each year, nearly 35000 Nepali children die before their fifth birthday, with almost two-thirds of these deaths occurr... more
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Current Zika Product Pipeline

World Health Organization (2016) C_WHO
3 March 2016
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Roadmap for introduction and roll‐out of Merck rVSV‐ZEBOV Ebola Virus Disease vaccine in African countries

World Health Organization WHO (2019) C_WHO
Revised working paper following AVAREF meeting February 2019. WHO has published a roadmap aiming to coordinate partners’ actions and contributions to the licensing and roll-out of Merck’s Ebola vaccine (VSV-ZEBOV) in African countries. The vaccine was developed during the West Africa Ebola epi... more
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Update on Ebola drug trial: two strong performers identified

World Health Organization WHO (2019) C_WHO
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Tackling Antimicrobial Resistance

EuroHealth Observer European Observatory on Health Systems and Policies Eurostation (2020) C2
The focus of the current quarterly edition of Eurohealth (from the European Observatory on Health Systems and Policies) is Antimicrobial Resistance (AMR) and contains the following articles: • Strengthening implementation of AMR national action plans • Fostering clinical developmen... more
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HIV/AIDS in the South-East Asia region: progress and challenges

R. Pendse; S. Gupta; D. Yu; S. Sarkar World Health Organization South-East Asia Region (2016) C_WHO
Journal of Virus Eradication 2016; 2 (Supplement 4): 1–6 Review
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The different types of COVID-19 vaccines

World Health Organization WHO (2020) C_WHO
This article is part four in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. Part two focused on the ingredients in a vaccine and the three clinical trial phases. Part three focused on the ste... more
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Informing vaccination programs: a guide to the design and conduct of dengue serosurveys

World Health Organization WHO (2020) C_WHO
In this document, recommendations are provided on designing and implementing a cross-sectional serosurvey using school-based sampling to estimate age-specific DENV seroprevalence to inform a country’s national dengue vaccination program. The document includes recommendations for methods for ... more
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Epidemiological review of TB disease in Sierra Leone

L. Anderson and E. Hamblion World Health Organisation (WHO) (2015) C_WHO
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National Guidelines on Medical Biotechnology 2010

Ministry of Health and Family Welfare Government of the People's Republic of Bangladesh (2011) C1
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Prevention and control of noncommunicable diseases in Kyrgyzstan: the case for investment

World Health Organization WHO, Regional Office of Europe (2017) C_WHO
Noncommunicable diseases (‎NCDs)‎ such as cancer, cardiovascular diseases, diabetes and chronic respiratory diseases and their risk factors are an increasing public health and development challenge in Kyrgyzstan. This report provides evidence through three analyses that NCDs reduce economic outp... more