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Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of t
...
he burden in these areas is due to infection with Plasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
more
The WHO Malaria Threats Map is an interactive online platform that showcases the latest global data on four critical biological threats to effective malaria control and elimination: mosquito insecticide resistance, Plasmodium falciparum hrp2/3 gene deletions, antimalarial drug resistance, and the
...
spread of invasive vector species. Designed for public health professionals and researchers, the map allows users to explore and filter data regionally, track emerging resistance patterns, and view visual trends. Its purpose is to inform strategies for surveillance, guide policy-making, and support efforts to eliminate malaria, particularly by anticipating and responding to biological challenges that could undermine control programs.
more
WHO Malaria Toolkit app
recommended
The Global Malaria Programme Toolkit app brings together the content of the latest World malaria report and of the consolidated WHO Guidelines for malaria as well as operational manuals and other technical documents – in one easy-to-navigate resou
...
rce.
more
Malaria remains a significant public health challenge in the South-East Asia Region, which bears the second highest malaria burden in the world.
Malgré ces progrès, le paludisme reste toutefois un problème de santé mondial important, avec environ 282 millions de cas et 610 000 décès en 2024, soit environ 9 millions de cas de plus que l'année précédente. La région Afrique de l'OMS continue de supporter la plus grande partie du farde
...
au, avec 11 pays représentant environ les deux tiers des cas et des décès dans le monde. Les progrès en matière de réduction du taux de mortalité lié au paludisme restent toutefois très insuffisants.
more
Este resumen ejecutivo ofrece una visión general completa de los mensajes clave, los datos y las tendencias del Informe mundial sobre la malaria 2025.
The webpage from the Pan American Health Organization (PAHO) discusses the heightened risk that individuals with noncommunicable diseases (NCDs)—such as cardiovascular diseases, diabetes, and canc
...
er—face regarding severe illness and mortality from COVID-19. It emphasizes the necessity of informing the public about these health risks and adapting healthcare services to ensure the continuity of essential NCD care during the pandemic. The page provides information and guidance for healthcare providers and the public on managing NCDs in the context of COVID-19, highlighting the importance of addressing NCDs and their risk factors with a medium- to long-term perspective.
more
The webpage from the Pan American Health Organization (PAHO) discusses the heightened risk that individuals with noncommunicable diseases (NCDs)—such as cardiovascular diseases, diabetes, and canc
...
er—face regarding severe illness and mortality from COVID-19. It emphasizes the necessity of informing the public about these health risks and adapting healthcare services to ensure the continuity of essential NCD care during the pandemic. The page provides information and guidance for healthcare providers and the public on managing NCDs in the context of COVID-19, highlighting the importance of addressing NCDs and their risk factors with a medium- to long-term perspective.
more
The report provides an update on the cholera outbreak in Haiti as of January and February 2024. A total of 79,411 suspected cases have been reported, with 4,608 confirmed cases and 1,172 deaths across all 10 departments. The most affected regions include Ouest, Centre, Artibonite, and Nord, with chi
...
ldren aged 1-9 being the most impacted. Despite a recent decline in reported cases, underreporting due to security issues remains a concern. Response efforts include coordination meetings, epidemiological surveillance, case management, WASH interventions, vaccination campaigns, and community engagement. However, logistical challenges, insecurity, and funding shortages are hindering effective response efforts.
more
The document titled "Manual for Stratifying Malaria Risk and the Elimination of Foci" by PAHO provides guidance for countries in the Americas on how to systematically assess and classify malaria transmission risk at subnational levels. It outlines a standardized approach to stratification and the id
...
entification of active transmission foci, helping public health authorities prioritize interventions, allocate resources efficiently, and implement targeted strategies to accelerate progress toward malaria elimination.
more
Todos los países de la Región de las Américas en los que la malaria es endémica han asumido el reto de eliminar la enfermedad y de poner en marcha medidas para orientar sus programas y estrategias de salud en esa dirección. En este manual se explica cómo ejecutar las medidas con vistas a logra
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r la eliminación de la malaria y prevenir su restablecimiento, mediante el aumento de la intensidad y la calidad de las medidas, la reorientación de las iniciativas, la reducción de los retrasos que favorecen la transmisión y un monitoreo adecuado que permita ajustar las intervenciones. En este sentido, se propone como primer paso estratificar el territorio —de modo que se puedan planificar y priorizar las intervenciones y grupos de población— para, a continuación, aplicar una medida de diagnóstico, tratamiento, investigación y respuesta como estrategia clave dirigida a hacer efectiva la eliminación de la enfermedad y a prevenir su restablecimiento en todos los estratos. Además, el documento trata de hacer operativo el concepto de vigilancia, como intervención promovida por la Organización Mundial de la Salud a través de la Estrategia Técnica Mundial contra la Malaria 2016-2030, y destaca la importancia de que las comunidades tengan acceso al diagnóstico y el tratamiento tempranos. Por último, en el manual también se incluyen aspectos de gestión y monitoreo que deben tenerse en cuenta para la eliminación de los focos de transmisión.
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All malaria-endemic countries in the Region of the Americas have taken on the challenge to eliminate the disease and to put in place measures to orient their health programs and strategies in that direction. This manual explains how to implement mea
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sures to achieve malaria elimination and prevent its reestablishment by increasing the intensity and quality of interventions, reorienting initiatives, reducing delays that favor transmission, and ensuring adequate monitoring to adjust interventions.
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Le Plan d’action pour l’élimination du paludisme 2021-2025 a été élaboré en consultation avec les pays et les partenaires régionaux comme cadre de référence pour orienter les efforts nationaux et les contributions des donateurs et partenaires dans le but d’éliminer la maladie dans la
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Région des Amériques. Le plan souscrit aux objectifs et aux piliers de la Stratégie technique mondiale de lutte contre le paludisme 2016-2030 adoptée par l’OMS, et présente également des éléments clés pour relever les défis spécifiques à la Région.
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The Plan subscribes to the goals and pillars of the WHO Global Technical Strategy against Malaria 2016-2030 (GTS), while presenting key elements to address the specific challenges of the Region.
O Plano de ação para a eliminação da malária 2021-2025 foi desenvolvido em consulta com países e parceiros regionais como um marco de referência para orientar os esforços dos países e as contribuições de doadores e parceiros em prol da eliminação desta doença nas Américas. O plano sub
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screve às metas e aos pilares da Estratégia técnica mundial para o paludismo 2016-2030, da Organização Mundial da Saúde, ao mesmo tempo em que apresenta elementos essenciais para enfrentar os desafios específicos da região.
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El Plan de acción para la eliminación de la malaria 2021-2025 ha sido elaborado en consulta con los países y asociados regionales como un marco de referencia para orientar las acciones de los países y las contribuciones de los donantes y de los asociados hacia la eliminación de la enfermedad en
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la Región de las Américas. El plan está en consonancia con los objetivos y pilares de la Estrategia técnica mundial contra la malaria 2016-2030 de la OMS, al tiempo que presenta elementos clave para afrontar los desafíos específicos de la Región.
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Esta nota técnica busca guiar a los programas nacionales de malaria y a las organizaciones implicadas en el apoyo de los esfuerzos para la eliminación de la malaria en la Región de las Américas, a fin de que intensifiquen las acciones políticas/estratégicas e implementen los cambios operativos
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necesarios para acelerar la eliminación de P. falciparum como parte de las estrategias nacionales para la eliminación de la malaria.
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This technical note provides guidance on actions to accelerate P. falciparum elimination in areas close to achieving this goal without compromising unified malaria elimination efforts (P. vivax - P. falciparum), while contributing to the country's ultimate goal of eliminating malaria overall.
The Manual for Indoor Residual Spraying in Urban Areas for Aedes aegypti Control is intended not only for operational personnel and middle and senior management of programs responsible for the prevention and control of Aedes-borne diseases, but also for the academic community involved in Aedes resea
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rch, private pest control personnel, and the general public.
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Manual para aplicar rociado residual intradomiciliario en zonas urbanas para el control de Aedes aegypti no solo está dirigido al personal operativo y los mandos medios y directivos de los programas de prevención y control de las enfermedades transmitidas por Aedes, sino también a la comunidad ac
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adémica relacionada con la investigación operativa sobre RRI-Aedes, a los controladores de plagas privados y al público en general.
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