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Publication Years
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Category
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Toolboxes
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6
Effective malaria case management requires quick access to diagnostics and antimalarial treatments to reduce illness and death. Artemisinin-based combination therapy (ACT) has been essential to malaria treatment since 2001, as it combines artemisini
...
n for rapid parasite reduction with a partner drug to ensure complete cure. However, resistance to antimalarial drugs, where parasites survive standard doses, threatens malaria control.
more
INTRODUCTION: Lower extremity peripheral artery disease (PAD) is increasing in prevalence in low- and middle-income countries creating a large health care burden. Clinical management may require substantial resources but little consideration has bee
...
n given to which treatments are appropriate for less advantaged countries.
EVIDENCE ACQUISITION: The aim of this review was to systematically appraise published data on the costs and effectiveness of PAD treatments used commonly in high-income countries, and for an international consensus panel to review that information and propose a hierarchy of treatments relevant to low- and middle-income countries.
EVIDENCE SYNTHESIS: Pharmacotherapy for intermittent claudication was found to be expensive and improve walking distance by a modest amount. Exercise and endovascular therapies were more effective and exercise the most cost-effective. For critical limb ischemia, bypass surgery and endovascular therapy, which are both resource intensive, resulted in similar rates of amputation-free survival. Substantial reductions in cardiovascular events occurred with use of low cost drugs (statins, ACE inhibitors, anti-platelets) and smoking cessation.
CONCLUSIONS: The panel concluded that, in low- and middle-income countries, cardiovascular prevention is a top priority, whereas a lower priority should be given to pharmacotherapy for leg symptoms and revascularisation, except in countries with established vascular units.
more
The CDC webpage "Types of Insulin" provides an overview of the various insulin types used in diabetes management, categorized by their onset, peak time, and duration of action. It explains terms like onset (how quickly insulin lowers blood sugar), p
...
eak time (when insulin is at maximum strength), and duration (how long insulin works to lower blood sugar). The page also discusses factors influencing insulin prescriptions, such as activity level, diet, blood sugar management, age, and individual insulin absorption rates.
more
The document provides comprehensive guidance for people with COPD, covering treatment and medication management, oxygen therapy, mucus control, exercise, smoking cessation, nutrition, associated conditions, and strategies to prevent exacerbations. I
...
t emphasizes patient education, self-management, and working closely with healthcare providers to enhance well-being and control of the disease.
more
The document provides practical guidance for individuals with COPD, covering topics such as medication management, oxygen therapy, mucus control, physical exercise, smoking cessation, nutrition, associated conditions, and how to prevent and manage e
...
xacerbations. It emphasizes the importance of patient education, adherence to treatment plans, and collaboration with healthcare providers to improve quality of life and disease outcomes.
more
In this guide, the African Palliative Care Association (APCA) has put together evidence‑based information on the use of specific opioids commonly used in the management of moderate‑to‑severe pain to manage both cancer and non‑cancer pain.
...
APCA hopes that this guide will be a useful tool in aiding health professionals at all levels of healthcare delivery to assess and manage pain using opioids. All opioids included in this guide are listed on the WHO model list of essential medicines but we remind readers that oral morphine is the standard opioid of choice for managing moderate‑to‑severe pain and we recommend that it should be made available at all times.
more
The primary goal of the guideline is to improve the quality of care and the outcome in people with type 2 diabetes in low-resource settings. It recommends a set of basic interventions to integrate management of diabetes into primary health care. It
...
will serve as basis for development of simple algorithms for use by health care staff in primary care in low-resource settings, to reduce the risk of acute and chronic complications of diabetes. The guideline was developed by a group of external and WHO experts, following the WHO process of guideline development. GRADE methodology was used to assess the quality of evidence and decide the strength of the recommendations.
more
The OpenWHO course titled "Interventions for Noncommunicable Diseases in Primary Health Care" provides guidance on screening, detection, diagnosis, and management of major noncommunicable diseases (NCDs) such as cardiovascular diseases, type 2 diabe
...
tes, chronic respiratory diseases (asthma and chronic obstructive pulmonary disease), and early cancer detection within primary health care settings. It emphasizes delivering high-impact essential NCD interventions through a primary healthcare approach to enhance early detection and timely treatment. This course is part of the SEARO NCD PEN-HEARTS series, which includes four courses aimed at enabling learners to plan and deliver NCD services effectively.
more
An integrated approach is particularly important for low-resource settings for efficient use of limited resources. The course contents will include risk factors, clinical course, guidance and protocols for diagnosis, management and referral as neede
...
d for NCDs in PHC. SEARO NCD PEN-HEARTS is a series of four courses with the other three courses focusing on Hearts of NCD: an integrated approach to management of NCDs in PHC, diabetic foot care and palliative care that will enable the learner to plan and deliver NCD services.
more
Now that you have a basic understanding of COPD, you may have some
additional questions. In this 201 guide, we will move beyond the basics.
You will find information and resources for the treatment and management
of COPD, associated conditions, a
...
nd even an action plan to help you avoid
exacerbations.
more
The "National Guideline for Cholera Surveillance and Outbreak Response" by the Ethiopian Public Health Institute (EPHI) provides a comprehensive approach to combating cholera outbreaks in Ethiopia. It emphasizes the importance of a multisectoral approach, including case
...
management, WASH measures, and the use of cholera vaccines. A key component is the establishment of Cholera Treatment Centers (CTCs) that provide 24/7 care. Additionally, the guideline stresses water quality monitoring and hygiene practices to prevent the spread of cholera and protect public health.
more
Addressing comorbidities and risk factors for tuberculosis (TB) is a crucial component of the World Health Organization (WHO)’s End TB Strategy. This WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities aims to support countries in scaling up people-centred care, base
...
d on the latest WHO recommendations on TB and key comorbidities, and drawing upon additional evidence, best practices and inputs from various experts and stakeholders obtained during WHO processes. It is intended for use by people working in ministries of health, particularly TB programmes and the relevant departments or programmes responsible for comorbidities and health-related risk factors for TB such as HIV, diabetes, undernutrition, substance use, and tobacco use, as well as programmes addressing mental health and lung health. This operational handbook is a living document and will include a separate section for each of the key TB comorbidities or health-related risk factors. The third edition includes guidance for HIV-associated TB, mental health conditions and diabetes, which are three conditions strongly associated with TB and which result in higher mortality, poorer TB treatment outcomes and negatively impact health-related quality of life. The operational handbook aims to facilitate early detection, proper assessment and adequate management of people affected by TB and comorbidities. Full implementation of this guidance is expected to have a significant impact on TB treatment outcomes and health-related quality of life for people affected by TB.
more
The article "Malaria – MSD Manual Professional Edition" provides a comprehensive overview of malaria, an infection caused by Plasmodium species. It describes symptoms such as fever, chills, and anemia, explains diagnostic methods like parasite detection in blood smears, and discusses treatment opt
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ions including artemisinin-based combination therapies. In addition, it outlines prevention strategies such as medical prophylaxis and mosquito control measures. The article is intended for medical professionals and offers detailed information on the pathophysiology, clinical presentation, and management of malaria.
more
The document "Classification and Referral Algorithm – iCCM Uganda" (2013) by Malaria Consortium provides a practical guide for community health workers to assess, classify, and manage common childhood illnesses in Uganda. It focuses on key symptoms such as fever, cough, diarrhoea, and danger signs
...
like convulsions or inability to drink. Based on these assessments, the guide helps determine whether a child needs urgent referral to a health facility or can be treated at home. It includes detailed treatment protocols using medicines like amoxicillin, ORS, zinc, Coartem, and rectal artesunate. The goal is to strengthen integrated community case management (iCCM) to reduce child mortality through early detection, appropriate treatment, and timely referral.
more
The 7th edition of the Orange Guide provides practical guidance to health workers on the front line of TB control. It includes sections on HIV, MDR-TB and a review of the recommended treatment regimens
Anaesthesia Tutorial of the Week
Case Management; Guide for Tutors
Handbook For Clinical Management Of Dengue
recommended
Clinical management handbook
The purpose of this pocketbook is to provide clear guidance on current best management practices for VHF across health-care facilities
