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Keeping communities at the centre of efforts to eliminate lymphatic filariasis: learning from the past to reach a future free of lymphatic filariasis

Krentel, A.; Gyapong, M.; McFarland, D.A.; Ogundahunsi, O.; Titaley, C.R.; Addiss, D.G. Oxford Academic - International Health (2021) CC

Since the launch of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) in 2000, more than 910 million people have received preventive chemotherapy for lymphatic filariasis (LF) and many thousands have received care for chronic manifestations of the disease. To achieve this, millions of c... more

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The Guide for Training Community Health Workers

Ministry of Health, Community Development, Gender, Elderly and Children, Government City - Mtumba (2021) CC2

For many years, Community Health Care Workers (CHWs) in Tanzania and Africa in general have played significant role in community health promotion. Their specific roles have been changing from time to time. However, their key roles have over time included giving health education and dissemination of ... more

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Ebola: GO 2.0

World Health Organization WHO (2018) C_WHO

All personnel responding to Ebola outbreaks need to have basic knowledge and skills in order to mount an effective response. The GO training package was developed for WHO deployees so they can work safely and effectively as part of the teams bringing outbreaks under control. The learning package con... more

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Climate Change and State-Level Health Impacts

NRDC (2022) CC

Climate change is altering seasonal patterns, making our summers hotter, and fueling increased flooding from coastal storms. As a result, we face more heat-related illnesses, air quality issues, food and water contamination, traumatic injuries, threats to our mental health, and infectious diseases. ... more

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Desinstitucionalización de la atención psiquiátrica en América Latina y el Caribe

Pan American Health Organisation PAHO (2021) C_WHO

This publication summarizes the facilitators and barriers that will be encountered in the deinstitutionalization process and identifies useful and proven interventions in Latin American and Caribbean countries. Four areas of work are identified with the respective guidelines or suggestions for actio... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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WHO good manufacturing practices for pharmaceutical products: main principles

World Health Organization WHO (2014) C_WHO

Licensed pharmaceutical products (marketing authorization) should be manufactured only by licensed manufacturers (holders of a manufacturing authorization) whose activities are regularly inspected by competent national authorities. This guide to GMP shall be used as a standard to justify GMP status,... more

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Health Financing Progress Matrix assessment, Kenya 2023: summary of findings and recommendations

Kenya Ministry of Health, World Health Organization (WHO) (2024) CC

This comprehensive HPFM report thoroughly explores Kenya’s health financing landscape. It provides an in-depth analysis of the current state of affairs and sheds light on required strategic changes in health financing. The report points out the need to improve public financial management within th... more

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Stratégie d’utilisation des substances naturelles dans la prise en charge des personnes vivant avec le VIH : expérience du Burkina Faso

Nikiéma J. B., K. Djierro, J. Simpore et al. Ethnopharmacologia (2009) C2

Au Burkina Faso, les personnes vivant avec le VIH (PvVIH) ont régulièrement recours à des substances naturelles pour traiter certaines infections opportunistes. C’est ainsi que le suc des feuilles fraîches de Mitracarpus scaber Zucc. ex Schult. & Schult. f. (Rubiaceae) et de Senna alata (L.) R... more

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Compendium of forgotten foods in Africa: A companion publication for Integrating Africa’s forgotten foods for better nutrition
recommended

Food and Agriculture Organization of the United Nations FAO (2024) CC

The Food and Agriculture Organization of the United Nations has launched a new Compendium of forgotten foods in Africa which is a first-of-its-kind comprehensive collection of 100 African forgotten food crops. Also referred to as neglected, underutilized or orphan crops, these species offer valua... more

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Hendra virus: Epidemiology dynamics in relation to climate change, diagnostic tests and control measures

Yuen K. Y.; Frase N. S.; et al (2021) C2

Hendra virus (HeV) continues to pose a serious public health concern as spillover events occur sporadically. Terminally ill horses can exhibit a range of clinical signs including frothy nasal discharge, ataxia or forebrain signs. Early signs, if detected, can include depression, inappetence, colic o... more

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A Guidance for Tuberculosis Prevention and Control in Indigenous Populations in the Region of the Americas

Pan American Health Organisation PAHO (2021) C_WHO

Tuberculosis continues to represent a severe public health problem in the Region of the Americas, even more so in the case of indigenous peoples, whose TB incidence is much higher than that of the general population. To achieve tuberculosis control in these communities, it is necessary to respond t... more

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West and Central Africa - A Region on the Move: Mobility Trends in West and Central Africa (January – December 2021)

International Organization for Migration IOM (2022) CC

The second edition of the “A Region on the Move” report provides an overview of population movement trends in West and Central Africa in 2021. It aims to provide a comprehensive overview of mobility in the region and showcase the versatility, multidimensionality and nuances of regional mobility ... more

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GETTING TO KNOW CEREBRAL PALSY: Module 2 - Evaluating Your Child

Hambisela - Towards Excellence in Therapy for Cerebral Palsy Cerebral Palsy Association (Eastern Cape) (2008) C2

A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 1 - Released March 2008

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COVAX Initiative
recommended

Gavi, the Coalition for Epidemic Preparedness Innovations (CEPI) and WHO (2021) C_WHO

COVAX is the vaccines pillar of the Access to COVID-19 Tools (ACT) Accelerator The ACT Accelerator is a ground-breaking global collaboration to accelerate the development, production, and equitable access to COVID-19 tests, treatments, and vaccines. COVAX is co-led by Gavi, the Coalition for Epide... more