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Key Considerations: Emerging evidence on shielding vulnerable groups during COVID-19

Schmidt-Sane M. SSHAP (2020) CC

Shielding is a term used to describe the protection of individuals at high risk of severe COVID-19 illness by separating them from the general population.

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Partnership for Evidence-Based Response for COVID-19 - Profile Dashboard

Partnership for Evidence-Based Response to COVID-19 (PERC) (2021) CC

PERC has developed a dashboard on Tableau to visualize multidisciplinary data and guide decision-makers on their country’s current performance of the COVID-19 response.

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Reproductive health priorities: evidence from a resource tracking analysis of official development assistance in 2009 and 2010

Hsu J.; Berman P.; Mills A. The Lancet (2013) CC

nformation is scarce about the extent to which official development assistance (ODA) is spent on reproductive health to provide childbirth care; support family planning; address sexual health; and prevent, treat, and care for sexually transmitted infections, including HIV. We analysed flows of ODA t ... more

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Financing the SDGs: Evidence in Four Countries

Jennifer Turner AidData at William & Mary (2019) CC

Achieving the Sustainable Development Goals (SDGs) will require the international community to mobilize significant additional financing over the next decade. Tracking and analyzing this funding is central to measuring progress and making more informed choices to direct financial flows where they wi ... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti ... ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Building the Evidence Base in Disability Research Summary

International Centre for Evidence in Disability (ICED) London School of Hygiene and Tropical Medicine (LSHTM) (2014) C2

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Treatment of tuberculosis - Annex 4 Evidence- to- decision tables

World Health Organization (2017) C_WHO

Guidelines for treatment of drug-susceptible tuberculosis and patient care Update 2017

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Oxford COVID-19 Evidence Service

Centre for Evidence-Based Medicine (CEBM); University of Oxford Centre for Evidence-Based Medicine (CEBM); University of Oxford (2020) C2

Accessed: 24.03.2020 The CEBM has committed its skills and expertise in evidence synthesis and dissemination to the effort against the current COVID-19 pandemic. This page will be updated regularly.

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Technical consultation to assess evidence on community-based delivery of intermittent preventive treatment in pregnancy for malaria

World Health Organization WHO (2023) C_WHO

Report of a virtual meeting 21–23 June 2022

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RTS,S/AS01 malaria vaccine current evidence, including efficacy, safety, feasibility and impact and update on R21/Matrix-M malaria vaccine

Hamel, M.J. World Health Organization WHO (2023) C_WHO

Presentation OPT-SMC malaria vaccine workshop - Jan 2023

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Implementing WHO evidence-based interventions for adolescents and young adults living with and affected by HIV

World Health Organization WHO (2024) C_WHO

Adolescents and young adults aged 10-24 remain underserved in the global response against HIV. Combination prevention, treatment and care programmes use a mix of evidence-based interventions to meet the current HIV prevention needs of adolescents an ... more

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Working Paper 46 - Aid, China, and Growth: Evidence from a New Global Development Finance Dataset

Dreher, A.; A. Fuchs; B. Parks et al. AidData at William & Mary (2017) CC

This paper introduces a new dataset of official financing—including foreign aid and other forms of concessional and non-concessional state financing—from China to 138 countries between 2000 and 2014. We use these data to investigate whether and to what extent Chinese aid affects economic growth ... more

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The diagnosis of asthma in children: An evidence-based approach to a common clinical dilemma

Masekala, R.; Risenga, S.M.; Kitchin, O.P. et al. South African Medical Journal (2018) CC

Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, as well as airway reversibility. The diagnosis of asthma in young children is limited by the inability to perform objective lung function testing in this group of patients and the wi ... more

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Mental Health and COVID-19: Early evidence of the pandemic’s impact

World Health Organization WHO (2022) C_WHO

scientific brief, 2 March 2022

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Posttraumatic Stress Disorder: Overview of Evidence-Based Assessment and Treatment

Lancaster, C.L., Teeters, J.B., Gros, D.F., Back, S.E. Journal of Clinical Medicine (2016) CC

Abstract: Posttraumatic stress disorder (PTSD) is a chronic psychological disorder that can develop after exposure to a traumatic event. This review summarizes the literature on the epidemiology, assessment, and treatment of PTSD. We provide a review of the characteristics of PTSD along with associa ... more

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Mobile health in Sierra Leone: Evidence and implications for health systems

the Government of Sierra Leone, the Medical Research Centre, the University of Sierra Leone, the Royal Tropical Institute (KIT), Text to Change, and MannionDaniels (2014) C1

Technical Brief

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Zika Virus and Birth Defects — Reviewing the Evidence for Causality

Sonja A. Rasmussen, M.D., Denise J. Jamieson, M.D., M.P.H., Margaret A. Honein, Ph.D., M.P.H., and Lyle R. Petersen, M.D., M.P.H. New England Journal of Medicine (2016) C3

published online April 13, 2016, DOI: 10.1056/NEJMsr1604338. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMsr1604338