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Pattern of Neurosurgical Procedures in Ethiopia: Experience from Two Major Neurosurgical Centres in Addis Ababa

M. Abebe; T. Munie; G. Lende; et al. East and Central African Journal of Surgery; Bioline international (2011) C2

East and Central African Journal of Surgery Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa ISSN: 1024-297X EISSN: 2073-9990 Vol. 16, Num. 1, 2011, pp. 104-110

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Situational Analysis Report on Antimicrobial Resistance in Pakistan

The Center for Disease Dynamics, Economics & Policy CDDEP (2016) C2

Pakistan Global Antibiotic Resistance Partnership (GARP) was formed in the wake of international and national efforts for AMR curtailment. A group of experts from microbiology, infectious diseases and veterinary medicine formed a core group at the organizational meet... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Health Services for Buruli Ulcer Control: Lessons from a Field Study in Ghana

Ackumey, M.M.; C. Kwakye-Maclean, E. O. Ampadu et al. PLoS Neglected Tropical Diseases (2011) CC

PLoS Negl Trop Dis 5(6): e1187. doi:10.1371/journal.pntd.0001187. Buruli ulcer (BU), caused by Mycobacterium ulcerans infection, is a debilitating disease of the skin and underlying tissue which starts as a painless nodule, oedema or plaque and could develop into painful and massive ulcers if left u... more

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Methicillin-ResistantStaphylococcus aureus(MRSA):Prevalence and Antimicrobial Sensitivity Pattern among Patients—A Multicenter Study in Asmara, Eritrea

Yohaness Garoy E., Y. Berhane Gebreab, O. Okoth Achila et al. Hindawi (2018) C2

Methicillin-resistant Staphylococcus aureus(MRSA) strainsor multidrug-resistant S.aureus, initially described in 1960s,emerged in the last decade as a cause of nosocomial infections responsible for rapidly progressive, potential fatal diseases including life-threatening pneumonia, necrotizing fascii... more

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WHO Immunological Basis for Immunization Series: Module 14: cholera

World Health Organization WHO (2010) C_WHO

This module is part of the WHO series The Immunological Basis for Immunization, which was initially developed in 1993 as a set of eight modules, comprising one module on general immunology and seven modules each devoted to one of the vaccines recommended for the Expanded Programme on Immunization, i... more

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WHO guidelines on hand hygiene in health care: a summary

World Health Organization WHO (2009) C_WHO

Confronted with the important issue of patient safety, in 2002 the Fifty-fifth World Health Assembly adopted a resolution urging countries to pay the closest possible attention to the problem and to strengthen safety and monitoring systems. In May 2004, the Fifty-seventh World Health Assembly approv... more

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Hand hygiene for all

UNICEF, WHO (2020) C_WHO

Three billion people – 40 per cent of the world’s population – do not have a place in their homes to wash their hands with water and soap. Three quarters of those who lack access to water and soap live in the world’s poorest countries and are amongst the most vulnerable: children and familie... more

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Resistant pathogens

BUKO Pharma-Kampagne (2020) C2

BUKO Pharma-Kampagne has investigated the causes and consequences of antibiotic resistance in India, South Africa, Tanzania and Germany. Together with our partners we collected data and did interviews with numerous stakeholders. The outcome is presented in a brochure that is now available in English... more

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Climate change and Human Health : risks and responses

World Health Organization (WHO) (2003) CC

Over the ages, human societies have altered local ecosystems and modified regional climates. Today the human influence has attained a global scale. This reflects the recent rapid increase in population size, energy consumption, intensity of land use, international trade and travel, and other human a... more

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Venezuela’s Humanitarian Emergency

Human Rights Watch (2019) C1

Large-Scale UN Response Needed to Address Health and Food Crises This report is based on interviews with more than 150 health care professionals, Venezuelans seeking or in need of medical care who recently arrived in Colombia and Brazil, representatives from international and nongovernmental humani... more

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Christian Responses to Health and Development

German Institute for Medical Mission (2014) C2

In 1964 medical mission was challenged and called to define its distinctiveness and its special role in the context of that particular time. The consultation "Tuebingen I" clearly stated: "The Christian church has a specific task in the field of health and healing"1, and developed a conce... more

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Infections of the nervous system

V. Parikh; V. Tucci; S. Galwankar PMC (US National Library of Medicine National Institutes of Health) (2012) C2

Int J Crit Illn Inj Sci. 2012 May-Aug; 2(2): 82–97. doi: 10.4103/2229-5151.97273 PMCID: PMC3401822 PMID: 22837896

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Impact of climate change on human infectious diseases: Empirical evidence and human adaptation

Xiaoxu Wu, Yongmei Lu, Sen Zhou et al. (2016) CC

Environment International Volume 86, January 2016, Pages 14-23 Climate change refers to long-term shifts in weather conditions and patterns of extreme weather events. It may lead to changes in health threat to human beings, multiplying existing health problems. This review examines the scientific e... more

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Quality criteria for the evaluation of climate-informed early warning systems for infectious diseases

World Health Organization WHO (2021) C_WHO

The frequency of infectious disease epidemics is increasing, and the role of the health sector in the management of epidemics is crucial in terms of response. In the context of infectious disease epidemics, the use of climate-informed early warning systems (EWS) has the potential to increase the eff... more

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Impact of migration on infectious diseases in Europe

European Academies Science Advisory Council (2007) C2

Statement Impact of migration on infectious diseases in Europe | August 2007 | 1-7

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Clinical utlity of peptide microarrys in the serodiagnosis of neglected tropical diseases in sub-Saharan Africa: protocol for a diagnostic test accuracy sytematic review

Vengesai A., Naicker T., Kasambala M., et al. BMJ Open (2021) C2

Neglected tropical diseases tend to cluster in the same poor populations, and to make progress with their control, they will have to be dealt with in an integrated manner. Peptide microarrays may be a solution to tese problems, where diagnosis for co-infection can be detected simultaneously using th... more

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Risk factors of Cholera mortality

Global Task Force On Cholera Control (GTFCC) (2022) CC

To better adapt current case management practices and address excess mortality in otherwise treatable cases will require better knowledge of the demographic characteristics of the patients and comorbidities which can make severe dehydration harder to tolerate physiologically. With this in mind, a ... more

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Safe use of personal protective equipment in the treatment of infectious diseases of high consequence

European Centre for Disease Prevention and Control (2014) C1

A tutorial for trainers in healthcare settings Version 2: 2 Dec 2014 "The document focuses on an extended set of PPE components, which includes goggles, respirators, gloves, coveralls and footwear. Used properly, these PPE components can provide effective protection even from airborne transmissi... more

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Key aspects of the global response to the COVID-19 crisis: an inventory one year after the official announcement of the pandemic

Rüppel, T. (2021) CC