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Abstract: Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health. A plethora of information concerning the chronic phase of human Chaga... more
Chagas disease, or American trypanosomiasis, is an illness that can cause serious heart and stomach problems. It is caused by a parasite. Chagas disease is common in Latin America, especially in poor, rural areas. It can also be found in the United States, most often in people who were infected befo... more
Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses to address the many outstanding rese... more
This report provides a review and analysis of the research landscape for three diseases – Chagas disease, human African trypanosomiasis and leishmaniasis – that disproportionately afflict poor and remote populations with limited access to health services. It represents the work of the disease re... more
To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Chagas disease. The patient-centred platform aims to f... more
Chagas disease affects 8-10 million people worldwide, mainly in Latin America. The current therapy for Chagas disease is limited to nifurtimox and benznidazole, which are effective in treating only the acute phase of the disease but with severe side effects. Therefore, there is an unmet need for new... more
Die Infektion wird durch nachtaktive, blutsaugende Raubwanzen übertragen. Während des Blutsaugens scheiden die infizierten Wanzen Trypanosomen aus, die Bindehaut, Schleimhäute, Abschürfungen und Hautverletzungen einschließlich der Bißwunde kontaminieren können. Die Übertragung kann auch durc... more
Two adjectives raise an issue for communicators working on Chagas disease (CD): “invisible and silent”. Two adjectives that can be ascribed to other neglected tropical diseases (NTD), but which are part of the essence of CD. Bringing CD out of its situation of neglect and oblivion is a mission e... more
How Chagas disease is transmitted video. Video available with spanish sub title
La enfermedad de Chagas es parasitaria y afecta a más de 6 millones de personas en el mundo. Como normalmente es asintomática durante años, los nuevos casos suelen no detectarse ni reportarse y la mayoría de las personas con la enfermedad no tiene conciencia de su condición. Se diagnostica ... more
Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi. About 6­–7 million people worldwide are estimated to be infected with T. cruzi. The disease is found mainly in endemic areas of 21 continental Lati... more
Principaux faits D’après les estimations, 6 à 7 millions de personnes dans le monde sont infectées par Trypanosoma cruzi (T. Cruzi), le parasite responsable de la maladie de Chagas. La plupart de ces personnes vivent en Amérique latine. La transmission à l’être humain se fait principalem... more
Datos y cifras Se calcula que en el mundo hay entre 6 y 7 millones de personas infectadas por el Trypanosoma cruzi, el parásito causante de la enfermedad de Chagas, la mayoría de ellas en América Latina. La infección por Trypanosoma cruzi se puede curar si el tratamiento se administra al poco ... more
El desarrollo, desde 1991, de las Iniciativas Subregionales de Control de la Enfermedad de Chagas, y los avances de conocimiento en materia de diagnóstico y manejo de la infección/enfermedad de Chagas, llevan a la necesidad ética, y operativamente imperiosa, de estructurar el diagnóstico, atenci... more
The Triatominae are vectors for Trypanosoma cruzi, the aetiological agent of the neglected tropical Chagas disease. Their distribution stretches across Latin America, with some species occurring outside of the Americas. In particular, the cosmopolitan vector, Triatoma rubrofasciata, has already been... more
Chagas disease is a tropical parasitic infection transmitted by crawling, blood-sucking insects (kissing bugs). You may have flu-like symptoms or none at all. But the disease can lead to life-threatening complications. With prompt treatment, most people with Chagas disease, also known as American tr... more
Chagas disease (American trypanosomiasis) is endemic in 21 countries of the Americas, where control is largely focused on elimination of the domestic insect vectors (Triatominae) coupled with measures to extend and improve the screening of blood donors in order to avoid tranfusional transmission. Th... more
Over 6 million people worldwide are infected with Trypanosoma cruzi, the protozoan that causes Chagas disease (CD). T. cruzi is transmitted by triatomine insects, congenitally, through uncontrolled blood donations and organ transplants, and via consumption of food or drink contaminated by triatomi... more
En el presente documento se comunica el progreso logrado en la Región hacia la eliminación de la transmisión maternoinfantil del VIH y la sífilis entre los años 2010 y 2017. Se trata también del primer informe regional sobre la eliminación de la transmisión maternoinfantil y durante la prime... more
Accessed on 28.02.2023