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Pregnancy often results in exclusion from clinical trials of antiretroviral (ARV) drugs, resulting in limited data on pharmacokinetics (PK), drug safety, and the efficacy of new ARV drugs in pregnancy and lactation. However, pregnancy, lactation, or the potential for pregnancy should not preclude th
...
e use of drug regimens that would be chosen for people who are not pregnant, unless adequate drug levels are not likely to be attained in pregnancy or known adverse effects outweigh potential benefits
more
le Sénégal continue d’être confronté à une crise alimentaire et nutritionnelle qui touche particulièrement le nord et l’est du pays. Selon les estimations faites en novembre 20151, plus de 2,4 millions de personnes sont en insécurité alimentaire (soit 17% de la population), dont 220 461
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seront en crise pendant la période de soudure 20162. le nombre d’enfants en situation de malnutrition aiguë pourrait être de plus de 407 500 en 2016, parmi lesquels plus de 86 000 en sévère3. les chocs climatiques tels que la sécheresse et le retard de démarrage de la saison pluvieuse ont affecté le nord du pays alors que dans d’autres zones les inondations ont affecté plus de 60 000 personnes4. l’épidémie de la maladie à virus Ebola (MVE) qui a sévi aux portes du pays a montré qu’un renforcement du système de surveillance épidémiologique ainsi que le renforcement des structures de santé sont requis.
more
Profiles of Peripheral CD4+T Cells Count during Antiretroviral Treatment in Senegalese Adults Infected by HIV: Impact of Therapeutic Associations
Niang M. S., R. Derwiche, B. Mbengue
Journal of Immunology, Infection & Inflammatory Diseases
(2017)
CC
Thirty-three years after its discovery, the Human Immunodeficiency Virus (HIV), responsible for the AIDS pandemic, remains a major public health problem despite advanced researches providing better diagnostic and therapeutic tools. The virus targets especially CD4+ T cells, leading to deficiency of
...
the immune system and altering therefore defense against infections and cancer cells. Antiretroviral
more
The Antimicrobial Resistance Benchmark has evaluated for the second time how the most important players in the antibiotic market are addressing the rise of resistance and the global need for appropriate access to antibiotics. Although we can see progress — it’s hanging by a thread.
We have reac
...
hed a tipping point where large and prominent drugmakers have retreated from the antibiotics field and smaller innovative biotech companies have gone bankrupt due to the poor financial rewards on offer.
more
Antimicrobial resistance (AMR) is an important public health concern shared by developed and developing countries. In developing countries the burden of infectious diseases is greater and exacerbated by limited access to, and availability and affordability of, antimicrobials required to treat infect
...
ions caused by AMR organisms. With drugs not listed on the essential drugs list (EDL), problems of increased morbidity, costs of extended hospitalisation and mortality are extremely serious. The problem of susceptibility to and spread of infections caused by multidrug-resistant (MDR) infectious agents is fuelled by factors such as limited access to clean water and sanitation to ensure personal hygiene, malnutrition, and the HIV/TB epidemic.
more
The CDAC Network commissioned a practice guide to draw both on their experiences and many others’ in order to document approaches, practices and tools to working with rumors. It is aimed primarily at humanitarian programme managers and field staff to provide them with practical tips on how to work
...
with rumors in their response programs in a way that is achievable amid competing demands.
Part One focuses on some of the theory behind rumors: the definition, nature and importance of rumors, and why we need to work with them.
Part Two explains the key steps and considerations to identifying and addressing rumous: listening, verifying and engaging.
Part Three examines different roles and responsibilities in working with rumous, and how anticipation, coordination and partnerships can enhance what you do.
more
Recent increases in family planning (FP) use have been reported among women of reproductive age in union (WRAU) in Senegal. However, trends have not been monitored among harder-to-reach groups (including adolescents, unmarried and rural poor women), key to understanding whether FP progress is equita
...
ble. We combined data from six Demographic and Health Surveys conducted in Senegal between 1992/93 and 2014. We examined FP trends over time among WRAU and subgroups, and trends in knowledge of FP and intention to use among women with unmet need for FP. Our results show that percent demand satisfied is lower among rural poor women and adolescents than WRAU, although higher among unmarried women. Marked recent increases have been observed in all subgroups, however fewer than 50% of women in need of FP use modern contraception in Senegal. Knowledge of FP has risen steadily among women with unmet need; however, intention to use FP has remained stable at around 40% since 2005 for all groups except unmarried women (75% of whom intend to use). Significant progress in meeting the need for FP has been achieved in Senegal, but more needs to be done particularly to improve acceptability of FP, and to strategically target interventions toward adolescents and rural poor women.
more
La troisième génération de la Stratégie de Coopération (SCP3) de l’OMS avec le Bénin, qui couvre la période 2016-2019, intègre les priorités des réformes engagées et les objectifs de développement durable (ODD ). Non seulement la Stratégie de Coopération avec le Bénin 2016-2019
...
intègre les priorités des réformes en cours au sein de l ’Organisation, y compris le Programme de transformation du Secrétariat de l ’OMS dans la Région africaine, mais cette SCP3 tient aussi compte des options de politique et stratégiques du secteur de la santé pour les cinq prochaines années.
more
This is a case-ascertained prospective investigation of all identified health care contacts working in a health care facility in which a laboratory confirmed 2019-nCoV infected patient (see 2.2 Study population) receives care. Note that this study can be done in health care facilities at all 3 level
...
s of a health system – not just in hospitals. It is intended to provide epidemiological and serologic information which will inform the identification of risk factors 2019-nCoV infection among health care workers.
There are three primary objectives of this investigation among health care workers in a health care setting where a 2019-nCoV infected patient is being cared for:
To better understand the extent of human-to-human transmission among health care workers, by estimating the secondary infection rate1 for health care worker contacts at an individual level.
To characterize the range of clinical presentation of infection and the risk factors for infection among health care workers.
To evaluate effectiveness of infection prevention and control measures among health care workers
To evaluate effectiveness of infection prevention and control programmes at health facility and national level
more
Household transmission investigation protocol for 2019-novel coronavirus (2019-nCoV) infection
recommended
The household transmission investigation is a case-ascertained prospective study of all identified household contacts of a laboratory confirmed 2019-nCoV infection (see 2.2 Study population). It is intended to provide rapid and early information on the clinical, epidemiological and virological chara
...
cteristics of 2019-nCoV.
There are three primary objectives of this household transmission study:
To better understand the extent of transmission within a household by estimating the secondary infection rate for household contacts at an individual level, and factors associated with any variation in the secondary infection risk.
To characterize secondary cases including the range of clinical presentation, risk factors for infection, and the extent and fraction of asymptomatic infections.
To characterize serologic response following confirmed 2019-nCoV infection (highly encouraged, but optional depending on laboratory capacity and resources)
more
South African Health Review 2019
recommended
22nd edition
The purpose of the SAHR has always been to analyse and assess progress and challenges in key areas of the health system, and to propose recommendations for improvement. We are pleased to continue this tradition in the 2019 edition, which presents a unique collection of perspectives on
...
the key challenges in implementing universal health coverage (UHC) in South Africa, as analysed by experts in various fields.
Each of the 20 chapters deals with aspects of the UHC journey, dedicated towards an equitable and inclusive national health system that leaves no-one behind. While some authors describe the fundamental changes and practical considerations required to reconfigure the country's health system, others have reflected on specific programmatic areas and have made recommendations from a National Health Insurance (NHI)/UHC lens.
more
Analyse du financement de la santé et réflexions sur le régime d'assurance maladie universelle au Bénin
Mathauer, I.; A. Ntamwishimiro Soumare, et B. my Semegan
Organisation mondiale de la Santé OMS
(2010)
C1
CARDIOVASCULAR AFRICA JOURNAL OF AFRICA
Volume 27, No 4, July/August 2016
Malar J (2017) 16:174 DOI 10.1186/s12936-017-1808-x
Background: Since 2004, artemisinin-based combination therapy (ACT) has been the first-line treatment for uncomplicated malaria in Benin. In 2016, a medicine outlet survey was implemented to investigate the availability, price, and market share of
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anti-malarial treatment and malaria diagnostics. Results provide a timely and important benchmark to measure future interventions aimed at increasing access to quality malaria case management services.
more
Aktuelle Zahlen zu Asylanträgen, zur ethnischen Herkunft und Religionszugehörigkeit der Asylbewerber, zum Dublinverfahren, zu Entscheidungen über Asylanträge, zum Flughafenverfahren sowie zu anhängigen Verfahren beim Bundesamt
This month 600 people reached Greece, mostly to Lesvos island. UNHCR with IOM and UNICEF welcomed the latest relocations of 49 unaccompanied children from Greece to Portugal and Finland and called for more. The need for such solutions is high as only one in four has a place in a shelter. The prematu
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re end of accommodation assistance may lead recognized refugees to become homeless.
more
