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What it is and what you can do
Rev. Oct16 770-10-0003
Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The
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disease is common in rural tropical communities in West and Central Africa, where access to proper health care is limited. Pathogenesis of the characteristic painless ulcers is linked to the elaboration by M. ulcerans of a lipid toxin called mycolactone that has potent cytopathic, immunosuppressive, and analgesic effects on a host of cells in cutaneous tissues. Mycolactone is known to profoundly inhibit secretion of a plethora of proteins that are essential for wound healing. Even though a combination antibacterial therapy of streptomycin and rifampicin for 8 weeks is effective for treatment, it relies on good and appropriate wound management to prevent secondary bacterial infections and improve healing. Evidence-based interventions for wound care in Buruli ulcer disease are often lacking and have relied on expert advice and recommendations. Surgical interventions are limited to debridement of necrotic tissue and grafting of extensive ulcers, usually after antibiotic therapy. Patients’ rehabilitation is an important component of care to reduce disabilities associated with the disease and proper integration into the community after treatment.
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Twenty-Fourth Annual Trachoma Control Program Review, Summary Proceedings
A Guide for Community Case Workers in OVC Programs. This guide is meant to help you, a community case worker or
facility case manager working on an orphans and vulnerable children (OVC) program, to
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understand your role in supporting
multi-month dispensing (MMD) of anti-retroviral (ARV) medicines for children and adolescents living with HIV (CLHIV/ALHIV).
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Accessed November 2017.
Overcoming Barriers to TB Control
Training Curriculum
August 2011
Tuberculosis (TB) is an infectious disease that usually affects the lungs, though it can affect any organ in the body. It can develop when bacteria spread through droplets in the air. TB can be fatal, but in many cases, TB is preventable
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and treatable. This report examines the human rights impact of the prevalence of Tuberculosis (TB) and Multi-drug-resistant tuberculosis (MDR-TB) among the Indigenous San peoples of Namibia. Combining political economy and root-cause methodology, the report explores the socioeconomic factors that make the San vulnerable to TB and limit their access to adequate health services.
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National Guidelines for Home Based Care Services
Ministry of Health and Social Welfare, National AIDS Control Programme, Tanzania
Ministry of Health and Social Welfare, Tanzania
(2010)
C1
The coronavirus disease 2019 (COVID-19) pandemic has created a global and gendered crisis that is compounding existing inequalities and disproporti
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onately affecting girls and women. Emerging evidence from the COVID-19 crisis in 2020 shows school closures, disruptions in essential services and rising poverty contributed to girls’ increased risk of female genital mutilation (FGM). School closures limited the monitoring and reporting of cases of FGM. Rising household monetary poverty may have contributed to families adopting negative coping mechanisms, including having girls undergo FGM as a precursor to marriage to reduce household costs. A report from the United Nations Population Fund (UNFPA) estimates 2 million additional cases of FGM by 2030 due to the pandemic.
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Guidance for Orphans and Vulnerable Children Programs
Global HIV control funding falls short of need. To maximize health outcomes, it is critical that national governments sustain reasonable commitments, and that international donor assistance be distr
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ibuted according to country needs and funding gaps. We develop a country classification framework in terms of actual versus expected national domestic funding, considering resource needs and donor financing. With UNAIDS and World Bank data, we examine domestic and donor HIV program funding in relation to need in 84 low- and middle-income countries. We estimate expected domestic contributions per person living with HIV (PLWH) as a function of per capita income, relative size of the health sector, and per capita foreign debt service.
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A technical guide for sputum smear microscopy, initiated by the International Union against Tuberculosis, is designed to be an easy to use reference standard for the collection, storage and transport of sputum specimens
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and for the examination of sputum smears by direct microscopy. This edition includes updates addressing bio-safety and quality assurance aspects of sputum smear microscopy.
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The Ministry of Health has developed the first version of the Service Standards and Service Delivery Standards for the health sector in Uganda. The main objective is to provide a common understanding of what is expected by the public, service users
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and service providers in ensuring provision of consistently high quality service delivery. These standards also provide a roadmap for improving the quality, safety and reliability of healthcare in Uganda.
The application of these standards is expected to improve transparency and accountability in service delivery; fairness and equity in service provision; building a culture of quality management; regulation, management and control of public and private providers; and management of expectations of service recipients. more
The application of these standards is expected to improve transparency and accountability in service delivery; fairness and equity in service provision; building a culture of quality management; regulation, management and control of public and private providers; and management of expectations of service recipients. more
The document is a report by an expert group that presents a framework for improving future pandemic preparedness and emergency response, particularly in the context of India but with relevance to global health systems. It analyzes lessons learned fr
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om COVID-19 and past epidemics, identifies key weaknesses in areas such as governance, surveillance, data management, research, and coordination, and proposes a comprehensive strategy to address them. The report emphasizes the importance of early detection, strong public health infrastructure, coordinated governance, scientific innovation, and international collaboration. A central idea is the ability to respond effectively within the first 100 days of an outbreak by having systems, resources, and policies already in place. Overall, it aims to strengthen resilience and ensure faster, more efficient responses to future health crises.
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The goal of the global outbreak response for monkeypox is to stop human-to-human transmission of monkeypox, with a priority focus on communities at high risk of exposure which may differ according to context, and to effectively use strong public hea
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lth measures to prevent onward spread of the disease. Judicious use of vaccines can support this response. This interim guidance, developed with the advice and support of the Strategic Advisory Group of Experts (SAGE) Working Group on smallpox and monkeypox vaccines, provides the first WHO recommendations on vaccines and immunization for monkeypox. Key points follow.
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Infectious diseases, such as COVID-19, can have a significant impact on children’s and their caregivers’
wellbeing beyond the disease itself. In terms of child protection, there are three main
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potential
secondary impacts:
- Neglect and lack of parental care.
- Mental health and Psychosocial distress.
- Increased exposure to violence, including sexual violence, physical and emotional abuse.
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The Private Sector Engagement Strategy on HIV, STIs and TB is a is a guide that is both comprehensive
and focused, and it is to be used by busines
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ses and corporations to actively participate in the HIV, STIs
and TB and Noncommunicable diseases (NCDs) response. The goal of this strategy is to develop a
culture in the workplace that actively promotes HIV, STIs and TB prevention, awareness, and support for
employees impacted by HIV, STIs and TB. The strategy incorporates several essential components, such
as those pertaining to prevention and education, accessibility to testing and treatment, reduction of stigma,
community participation, strategic alliances, employee empowerment and wellness, and data-driven
decision-making
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Trop. Med. Infect. Dis. 2018, 3, 72;
The study identified some key determinants of untimely and incomplete childhood vaccinations in the context of Bangladesh. The findings will contribute to the improvement of age-specific vaccination ... and support policy makers in taking the necessary control strategies with respect to delayed and early vaccination in Bangladesh.
https://doi.org/10.3390/tropicalmed3030072 more
The study identified some key determinants of untimely and incomplete childhood vaccinations in the context of Bangladesh. The findings will contribute to the improvement of age-specific vaccination ... and support policy makers in taking the necessary control strategies with respect to delayed and early vaccination in Bangladesh.
https://doi.org/10.3390/tropicalmed3030072 more
