The Global Antibiotic Resistance Partnership (GARP) aims to address the challenge of antibiotic resistance by developing actionable Policy Proposals in Vietnam and four other low- and middle-income countries: China, India, Kenya and South Africa. GARP will develop the evidence base for Policy action... on antibiotic resistance and identify policy opportunities where research, advocacy and information have the best chance of slowing the development and spread of resistance.
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Historically, the discovery of the sulfa drugs in the 1930s and the subsequent development of penicillin during World War II ushered in a new era in the treatment of infectious diseases. Infections that were common causes of death and disease in the pre-...antibiotic era - rheumatic fever, syphilis, cellulitis and bacterial pneumonia - became treatable, and over the next 20 years most of the classes of antibiotics that find clinical use today were discovered and changed medicine in a profound way. The availability of antibiotics enabled revolutionary medical interventions such as cancer chemotherapy, organ transplants and essentially all major invasive surgeries from joint replacements to coronary bypass. Antibiotics, though, are unique among drugs in that their use precipitates their obsolescence. Paradoxically, these cures select for organisms that can evade them, fueling an arms race between microbes, clinicians and drug discoverers.
Wright BMC Biology 2010, 8:123 http://www.biomedcentral.com/1741-7007/8/12
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Strengthening Parmaceutical Systems. 2nd edition
Des milliers de personnes meurent chaque jour des suites d’infections acquises au cours des procédures de soins.
The Infection Prevention and Control (IPC) Legal Framework comes before the Specialized Technical Committee on Health and Drug Control for adoption and endorsement. The IPC Legal Framework is designed to guide Member States in the review and strengthening of laws and policies that support IPC at bot...h the national level and in healthcare facilities. In developing this IPC Legal Framework, the Africa Centres for Disease Control and Prevention (Africa CDC)
is furthering its mandates to harmonize disease control and prevention policies and promote the prevention and control of diseases by building capacity of public health institutions in Members States.
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La publication fournit une vue d'ensemble et une analyse des instruments internationaux qui établissent des normes relatives à l'utilisation des antimicrobiens dans les secteurs humain, animal et végétal, et à leur rejet dans l'environnement. L'objectif de ce document est d'identifier les instr...uments et les normes existants afin de guider leur mise en œuvre et d'éclairer les discussions et l'orientation des futurs instruments internationaux relatifs à l'utilisation des antimicrobiens
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La publicación ofrece una visión general y un análisis de los instrumentos internacionales que establecen normas relacionadas con el uso de antimicrobianos en los sectores humano, animal y vegetal, y su liberación en el medio ambiente. El propósito del documento es identificar los instrumentos ...y normas existentes a fin de orientar tanto su aplicación como informar los debates y la dirección de futuros instrumentos internacionales relacionados con el uso de antimicrobianos.
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Brochure for General public
The World Health Organization was requested by Member States to develop a global priority pathogens list (global PPL) of antibiotic-resistant bacteria to help in prioritizing the research and development (R&D) of new and effective antibiotic treatments. To date, the selection of pathogens for R&D ac...tivities has been largely guided by small and large pharmaceutical companies according to a variety of parameters, such as perceived/unmet medical need, pressure of investors, market size, scientific discovery potential, and availability of specific technologies. Previous PPLs, issued by the Centers for Disease Control and Prevention.
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Ce document présente le Plan d’action de la FAO contre la résistance aux antimicrobiens 2021-2025, qui encadre les activités d’endiguement dans les secteurs de l’alimentation et de l’agriculture à l’échelle mondiale. À travers cette initiative, l’Organisation des Nations Unies pour... l’alimentation et l’agriculture (FAO) souhaite accélérer l'élaboration et la mise en application des plans d’action nationaux de lutte contre la résistance aux antimicrobiens en mettant l’accent sur les priorités stratégiques et les domaines d’expertise pouvant bénéficier de son soutien.
Disponible en: Arabe, Russe, Anglais, Espagnol, Chinois
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تلخِّص هذه الوثيقة خطة عمل منظمة الأغذية والزراعة بشأن مقاومة مضادات الميكروبات للفترة 2021-2025، والتي تمثِّل خريطة طريقٍ من أجل تركيز الجهود العالمية على التصدِّي لم...قاوَمة مضادات الميكروبات في القطاعات الغذائية والزراعية. وتتوخى هذه الخطة المساعدة في تسريع التقدُّم المُحرز في وضع وتنفيذ خطط عمل وطنية متعددة القطاعات معنيّة بمعالجة مقاوَمة مضادات الميكروبات، وذلك عبر لفتِ الانتباه إلى الأولويات الاستراتيجية ومجالات الخبرة للدعم الذي تقدّمه منظمة الأغذية والزراعة.
Available in English, Arabic, Russian, French, Spanish, Chinese
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How do they work in an ICC to prevent or mitigate nosocomial infections?
Are you clear that we can all do something to avoid them?
A simple hand wash can make a difference.
Inés Lavega has a degree in nursing and worked for more than 8 years at the CTI of Hospital Maciel, the first public hospit...al in Uruguay.
She tells us about the intense work of nursing, to control infections.
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The Global AMR R&D Hub collects and presents information on AMR R&D investments, products and market interventions. To position itself as the key knowledge centre for AMR R&D the work of the Hub is strategically aligned into three key pillars that encompass guiding and supporting evidence-based deci...sion making; enhancing collaboration and coordination; and promoting awareness, knowledge and visibility in the field.
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Washing hands is the best way to prevent the spread of germs and diseases. Dirty hands can carry pathogenic germs that can sicken a person or spread diseases to others. Microorganisms such as bacteria, viruses, parasites, fungi and various chemicals can enter our bodies directly when we touch our fa...ce, eyes, nose or mouth or may enter indirectly, when our dirty hands stain surfaces touched by others or where food is prepared. The habit of washing hands with soap and water constitutes the first line of defense against the spread of many diseases, from the common cold or diarrhea to more serious illnesses such as meningitis, influenza or hepatitis as well as many other diseases. This 2-D animation describes the importance of hand washing.
Available in different languages: Francais; Espagnol; Portuguese....
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AWaRe Website with different information material
BMJ Global Health Vol.4 (2019 no.4
The Drug Resistance Index (DRI) is proposed as measure of antibiotic effectiveness in a given country, by combining, in a single metric the use of various antibiotic groups and the resistance proportions of several pathogens.It is a complicated measure that gives ...results that cannot be understood by common knowledge and logic. The DRI conveys a wrong message.
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The aim of the Toolbox is to provide inspiration and guidance on what can be done to address the pressing issue, based on scientific evidence and experiences gathered from those working in the field across the globe. The Toolbox is built on what has been done in the past in a variety of settings and... is aligned with ongoing and current initiatives. Throughout the Toolbox, a narrative text guides the user on how to work with the problem, combining practical advice with examples from the field, and providing links to external resources. Many resources can be adapted and implemented in a variety of contexts.
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dades infecciosas. Los antimicrobianos eficaces son imprescindibles para las medidas preventivas y curativas, para proteger a los pacientes frente a enfermedades potencialmente mortales y para garantizar que se puedan llevar a cabo procedimientos complejos, como la cirugía y la quimioterapia, con e...scasos riesgos. Sin embargo, el mal uso y el abuso sistemático de estos fármacos en la medicina y la producción de alimentos han puesto en riesgo a todas las naciones. Hay pocos productos de recambio en fase de investigación y desarrollo. Sin medidas armonizadas e inmediatas a escala mundial avanzamos hacia una era posantibiótica en la que infecciones comunes podrían volver a ser mortales.
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Mit diesem E-Learning Kurs bietet die Pharma-Kampagne Bildungsmaterial zum Thema Antibiotika-Resistenzen. Das Thema ist nicht nur in der Humanmedizin relevant, sondern auch im Bereich Landwirtschaft und Nutztierhaltung, bei der ländlichen Entwicklung, beim Gewässerschutz, der Trinkwasserversorgung... oder der Ernährungssicherheit.
Informative Texte, anschauliche Länderbeispiele und nützliche Links liefern einen umfassenden Überblick über die aktuelle globale Problemlage. Berücksichtigt werden dabei sämtliche Anwendungsbereiche und Errungenschaften, aber auch die verschiedensten Risiken, die mit dem Gebrauch von Antibiotika einhergehen. Ganz im Sinne des OneHealth-Ansatzes werden dabei neben der Humanmedizin auch die Veterinärmedizin, die Antibiotika-Produktion oder auch Umweltaspekte angesprochen.
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