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“I would love if there was a young woman to encourage us, to ease our anxiety which we would have if we were alone”: Adapting the Mothers2Mothers Mentor Mother Model for adolescent mothers living with

N. B. Carbone; J. Njala; D. J. Jackson; et al. PLOS One; PubMed.gov (2019) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0217693 June 7, 2019

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HIV prevalence and determinants of loss-to- follow-up in adolescents and young adults with tuberculosis in Cape Town

P. Mulongeni; S. Hermans; J. Caldwell; et al. PLOS One (2019) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0210937 February 5, 2019

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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Development and validation of DSM-5 based diagnostic tool for children with Autism Spectrum Disorder

Sheffali Gulati , Jaya Shankar Kaushik, Lokesh Saini, et al. (2019) CC

PLoSONE 14(3):e0213242.https://doi.org/10.1371/journal.pone.0213242

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Quality of Prevention of Mother to Child Transmission (PMTCT) of HIV Services in Public Hospitals of Hadiya Zone, Southern Ethiopia

B. B. Bachore; F. Tafese; F. Gebissa; et al. Health Systems and Policy Research; iMedPub (2018) C2

2018 Vol.5 No.2:73 DOI: 10.21767/2254-9137.100092 Health Systems and Policy Research ISSN 2254-9137

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Impact of a Family Clinic Day intervention on paediatric and adolescent appointment adherence and retention in antiretroviral therapy: A cluster randomized controlled trial in Uganda

J. C. Graves; Peter Elyanu; C. J. Schellack; et al. PLOS One (2018) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0192068 March 9, 2018

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Propelling the Pediatric HIV Therapeutic Agenda With Science, Innovation, and Collaboration

E. J. Abrams; J. Ananworanich; M. Archary; M.N. Ngongondo; P. Brouwers J Acquir Immune Defic Syndr; Pub Med (2018) C2

J Acquir Immune Defic Syndr Volume 78, Supplement 1, August 15, 2018

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Expanding the Single-Visit Approach for Cervical Cancer Prevention: Successes and Lessons From Burkina Faso

Ouedraogo Y., Furlane G., Fruhauf T. et al. Global Health: Science and Practice (2018) CC

Background: Cervical cancer accounts for 23% of cancer incidence and 22% of cancer mortality among women in Burkina Faso. These proportions are more than 2 and 5 times higher than those of developed countries, respectively. Before 2010, cervical cancer prevention (CECAP) services in Burkina Faso wer...e limited to temporary screening campaigns. Program Description: Between September 2010 and August 2014, program implementers collaborated with the Ministry of Health and professional associations to implement a CECAP program focused on coupling visual inspection with acetic acid (VIA) for screening with same-day cryotherapy treatment for eligible women in 14 facilities. Women with larger lesions or lesions suspect for cancer were referred for loop electrosurgical excision procedure (LEEP). The program trained providers, raised awareness through demand generation activities, and strengthened monitoring capacity. Methods: Data on program activities, service provision, and programmatic lessons were analyzed. Three data collection tools, an individual client form, a client registry, and a monthly summary sheet, were used to track 3 key CECAP service indicators: number of women screened using VIA, proportion of women who screened VIA positive, and proportion of women screening VIA positive who received same-day cryotherapy. Results: Over 4 years, the program screened 13,999 women for cervical cancer using VIA; 8.9% screened positive; and 65.9% received cryotherapy in a single visit. The proportion receiving cryotherapy on the same day started at a high of 82% to 93% when services were provided free of charge, but dropped to 51% when a user fee of $10 was applied to cover the cost of supplies. After reducing the fee to $4 in November 2012, the proportion increased again to 78%. Implementation challenges included difficulties tracking referred patients, stock-outs of key supplies, difficulties with machine maintenance, and prohibitive user fees. Providers were trained to independently monitor services, identify gaps, and take corrective actions. Conclusions: Following dissemination of the results that demonstrated the acceptability and feasibility of the CECAP program, the Burkina Faso Ministry of Health included CECAP services in its minimum service delivery package in 2016. Essential components for such programs include provider training on VIA, cryotherapy, and LEEP; provider and patient demand generation; local equipment maintenance; consistent supply stocks; referral system for LEEP; non-prohibitive fees; and a monitoring data collection system. more

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HIV drug resistance patterns in pregnant women using next generation sequence in Mozambique

Rupérez et al. (2018) CC

This study aimed to understand the patterns of HIV drug resistance in pregnant women in Mozambique. This might help in tailoring optimal regimens for prevention of mother to child transmission of HIV (pMTCT) and antenatal care.

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It’s better together! European perspective on benefits and challenges associated with cross-border health communication campaigns

Rodrigues R., S. Ilinca, K. Schulmann PLOS ONE (2018) C1

PLOSONE| https://doi.org/10.1371/journal.pone.0204882October17,2018

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Neurodevelopmental disorders in children aged 2–9 years: Population-based burden estimates across five regions in India

N. K. Arora; , M. K. C. Nair; S .Gulati; et al. Plos Medicine (2018) CC

PLoS Med 15(7): e1002615. https://doi.org/10.1371/journal. pmed.1002615

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Multisectoral prioritization of zoonotic diseases in Uganda, 2017: A One Health perspective

Sekamatte, M.; V. Krishnasamy, L.Bulage et al. PLOS journals (2018) CC

PlosOne https://doi.org/10.1371/journal.pone.0196799; Zoonotic diseases continue to be a public health burden globally. Uganda is especially vulnerable due to its location, biodiversity, and population. Given these concerns, the Ugandan government in collaboration with the Global Health Security Age... more