The Annual Report summarizes what has been achieved in the year 2022, how WHO supported the country priority, how WHO took the lead in health in bringing together partners to help the country achieve its strategic goals as a result be on track on its commitment on the SDG goals. The report also high...lights what were the gaps in the year there by subsequent planning years should consider the challenges for better results.
more
En tant que département technique de l'OMS chargé du paludisme, le Programme mondial de lutte contre le paludisme a un rôle important à jouer dans la conduite de la riposte mondiale contre cette maladie. Grâce à ses actions directes et à son réseau, il peut façonner l'écosystème du paludi...sme et avoir un impact au niveau des pays. Dans cette optique, le Programme mondial de lutte contre le paludisme a élaboré une stratégie opérationnelle décrivant ses priorités pour la période 2024-2030 et les 4 leviers stratégiques pour contrôler et éliminer le paludisme qui relèvent de manière décisive du mandat du Programme : normes et critères, nouveaux outils et innovation, informations stratégiques axées sur les résultats et leadership. La stratégie décrit la façon dont le Programme mondial de lutte contre le paludisme se transformera également en la mise en place d’une collaboration plus efficace avec d’autres programmes, les bureaux régionaux et pays ainsi que les partenaires, en s’appuyant sur les enseignements tirés du treizième programme général de travail de l'OMS (GPW13) et des priorités du GPW14.
more
Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P...lasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
more
Report of a virtual meeting 21–23 June 2022
2nd edition. The purpose of this document is to present updated standardized protocols that P. falciparum-endemic countries can use to determine the prevalence of parasites with pfhrp2/3 gene deletions causing negative HRP2 RDT results among symptomatic falciparum patients. The findings should be us...ed to guide RDT selection; more specifically when to shift away from exclusive use of HRP2 to detect P. falciparum infections.
more
The aim of this protocol is to support the conduct of entomological comparative efficacy assessments for vector control products and the associated non-inferiority analysis. This evidence is used to inform discussions within the guidelines development context as to whether a new vector control prod...uct should be considered as covered by one or more existing WHO recommendations or not. Alternatively, the evidence may inform the extension of an existing WHO recommendation or the development of a new one, provided that non-inferiority is demonstrated
more
This document outlines the best practices for mosquito control and surveillance in United Nations duty stations affected by mosquito-borne diseases. It sets out an integrated vector management (IVM) approach combining environmental, biological, mechanical, chemical and personal protection strategies... to reduce mosquito populations and the transmission of diseases. Key elements include targeted control of larval and adult mosquitoes, the proper use of insecticides, community engagement, and ongoing surveillance.
more
The purpose of the guideline is to provide information to stakeholders on the necessary requirements for a complete prequalification dossier for insecticide-treated nets (ITNs). Its aim is to establish the baseline for dossier requirements which are necessary to assess ITN products for the purposes ...of prequalification, describe the data requirements for fulfilling each dossier module, and to provide standardized information for applicants and testing facilities generating data for ITN prequalification dossiers. The document is supported by implementation guidance documents which provide specific information and considerations for how applicants may approach the generation of supporting information and compilation of a complete product dossier.
more
The new WHO guidelines provide clinical management recommendations for four of the most widespread arboviruses affecting humans: dengue, chikungunya, Zika, and yellow fever.
An integrated approach is vital, as these four diseases often present with similar symptoms, especially in the early stages... of infection, and multiple arboviruses may circulate simultaneously in certain regions. This makes clinical differentiation challenging, particularly where diagnostic testing is not readily available.
This guideline is available in online format on the MAGICapp platform
more
Despite being a preventable and curable infectious disease, tuberculosis (TB) has continued to elude global controll efforts. In 2023, 8.2 milion people with TB were diagnosed and notified to the WHO, the hightest number ever reported since WHO began tracking.
In line with the Defeating meningitis by 2030: a global road map, the WHO guidelines on meningitis diagnosis, treatment and care Executive Summary provides a summary of the evidence-based recommendations for the clinical management of children and adults with community-acquired meningitis, including... acute and long-term care. Meningitis poses a significant public health threat, despite successful efforts to control the disease globally. The burden of morbidity and mortality from meningitis remains high, particularly in low- and middle-income countries and in settings experiencing large-scale, disruptive epidemics.
more
This publication provides an overview of evidence and guidance on the growing challenge of workplace heat stress in the context of climate change. It highlights the health and productivity risks faced by billions of workers, especially in manual labor sectors. The report details the physiological, s...ocioeconomic, and mental health impacts of heat stress and outlines evidence-based strategies for prevention and mitigation. It emphasizes the need for occupational heat action programmes, stakeholder collaboration, and tailored interventions to protect vulnerable workers, reduce productivity losses, and support sustainable development in a warming world.
more
Tobacco mythbusters: tools for debunking common myths promoted by the tobacco industry
This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
This report was developed by the WHO TB Vaccine Accelerator Finance and Access working group, co-led by WHO, Gavi and the Government of South Africa. It sets out the working group’s shared vision for equitable access to novel TB vaccines and will advance a shared understanding of the current lands...cape and its possible evolution in the future. It identifies six urgently needed solutions to accelerate access and financing and highlights the roles of different stakeholders to support the implementation of these solutions.
more
WHO MiNDbank is an online platform bringing together country and international resources, covering mental health, substance abuse, disability, general health, human rights and development. It is part of WHO’s QualityRights campaign to end violations against people with mental disabilities. MiNDban...k aims to facilitate dialogue, advocacy and research, to promote reform in these areas in line with international human rights and best practice standards.
more
Ambulatory care and infectiousness in tuberculosis (Russian Version)
Одна из ключевых целей профилактики и лечения туберкулеза (ТБ) - сделать их более ориентированными на людей, что означает даль...нейшее расширение и совершенствование моделей амбулаторного лечения в странах Восточной Европы и Центральной Азии. Эта записка предназначена для того, чтобы напомнить заинтересованным сторонам доказательства, свидетельствующие о том, что амбулаторная помощь возможна и безопасна
more