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The handbook includes evidence-based mental health interventions, drawn from the WHO mhGAP guidelines for mental, neurological, and substance use disorders (3), particularly those listed in the UHC Compendium. Evidencebased interventions to reduce population health-related stigma and discriminatio ... more
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to ... more
Technical Brief
Esc Anna Nery 2024;28:e20240093
A practical toolkot
In 2022, WHO published the Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations. These guidelines outline a public health response to HIV, viral hepatitis and sexually transmitted infections (STIs) for 5 key populations (men who have s ... more
Policy brief. In this policy brief, we give an update on those parts of the guidelines which are relevant for sex workers
These guidelines focus on the collection and use of person-centred data across the HIV cascade – from prevention, testing and treatment to longer-term health care – building upon 2017 and 2020 strategic information guidelines. The updated guidelines present a standard minimum dataset, priority i ... more
Operational requirements for implementing WHO recommendations in digital systems. 2nd edition. To ensure that countries can effectively benefit from digital health investments, “digital adaptation kits” (DAKs) are designed to facilitate the accurate reflection of WHO’s clinical, public health ... more
National Guidelines
Preprint VeriXiv 2025, 2:226 Last updated: 20 OCT 2025
EDCTP Stakeholder meeting
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV document is published in an electronic format and updated as relevant changes in prevention and treatment recommendations occur.
Dosing Recommendations for Prevention and Treatment
Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
This issue brief provides information about TB and HIV clinical trials and research programs impacted by U.S. government funding disruptions, and proposes urgent actions that donor agencies, governments, and philanthropies can take to preserve scientific advances underway and prevent the collapse ... more
Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV K-19 Tuberculosis/HIV Coinfection Updated: September 12, 2024 Key Considerations and Recommendations
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
A toolkit for health facilities. This toolkit highlights successful differentiated-care approaches implemented in a number of settings and countries in sub-Saharan Africa. The toolkit will be further updated as more experience is gained with these and similar approaches
Prevention of mother-to-child HIV transmission (PMTCT) has been a success in many respects but there is still much to do to eliminate mother-to child transmission (MTCT), particularly in low antiretroviral therapy (ART) coverage areas and in the postnatal phase. The success of PMTCT is highly dep ... more