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Preprint VeriXiv 2025, 2:226 Last updated: 20 OCT 2025
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
Technical Document
This facilitator manual is aimed at trainers of a three-day
‘Integrating VAC prevention and response into HIV settings’
course. It is for use by all facilitators who are delivering the
training.
National Policy
The Global Aids Strategy 2026-2031
recommended
United- Towards Ending AIDS. The Global AIDS Strategy 2026-2031 focuses global efforts for the future of the AIDS response to end AIDS as a public health threat by 2030 and sustain the HIV response after 2030. This is a strategy uniting the world.
The Strategy will shape the June 2026 United Natio
...
ns General Assembly High-Level Meeting on Ending AIDS and its political declaration. It provides all actors in the field with guidance to overcome the challenges and to ensure effective country-led AIDS responses. The Global AIDS Strategy 2026-2031 includes new global targets for 2030 and resource needs estimates.
more
The guide presents a structured framework covering assessment and planning, service delivery models, integration with broader health and social services, monitoring, and sustainability. It emphasizes community leadership, human rights, equitable access and adaptation to local contexts, including clo
...
sed settings. Practical tools are included to support implementation and accelerate progress towards global targets for controlling HIV and eliminating viral hepatitis epidemics.
more
Early Warning and Response to Outbreaks and other Public Health Events: A Guide provides practical guidance for strengthening early warning functions within existing public health surveillance systems in WHO’s South-East Asia Region. The document explains how countries can detect, verify, and resp
...
ond rapidly to outbreaks and other unusual public health events in line with the International Health Regulations (2005). It describes the five key steps of an Early Warning and Response (EWAR) system—information collection, signal detection, event verification, response, and communication—and outlines how to set alert thresholds, identify signals, and ensure timely reporting. The guide also includes recommendations for monitoring and evaluating system performance to improve timeliness, sensitivity, and overall effectiveness in preventing and controlling public health threats.
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Populations affected by emergencies are continually at risk of outbreaks of epidemic-prone diseases and other public health hazards. This operational guidance aims to guide decision-making on when and how to implement and strengthen Early Warning Alert and Response (EWAR) in preparation for and resp
...
onse to emergencies. Each module aims to provide updated operational guidance for EWAR practices, which may be more easily understood and applied during emergencies. Through its application, this operational guidance aims to contribute to:
- earlier detection of acute public health events
- earlier and more effective response
- reduced impact of emergencies on health
- increased trust of the population in the (public) health system
- fulfilling our collective commitments to the International Health Regulations (IHR,
2005).
This guidance was developed jointly by 69 experts from more than 20 organizations from global level to country level.
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Southern African Journal of HIV Medicine
PLoS ONE 18(12): e0295920. https://doi.org/10.1371/journal.pone.0295920. PLHIV were largely unaware and sceptical of U = U as the message appeared to contradict
the mainstream HIV prevention clinical guidance.
The Private Sector Engagement Strategy on HIV, STIs and TB is a is a guide that is both comprehensive
and focused, and it is to be used by businesses and corporations to actively participate in the HIV, STIs
and TB and Noncommunicable diseases (NCDs) response. The goal of this strategy is to devel
...
op a
culture in the workplace that actively promotes HIV, STIs and TB prevention, awareness, and support for
employees impacted by HIV, STIs and TB. The strategy incorporates several essential components, such
as those pertaining to prevention and education, accessibility to testing and treatment, reduction of stigma,
community participation, strategic alliances, employee empowerment and wellness, and data-driven
decision-making
more
The decriminalization of drug use and possession for personal use, when implemented effectively, is a critical element in a human rights and public health-based HIV response. The group of countries that have adopted decriminalization models spans all continents. This document brings together differe
...
nt approaches to and experiences of decriminalization of drug use and possession for personal use and provides recommendations for countries to ensure an enabling environment for the HIV response.
more
The document provides practical guidelines for conducting a national disaster risk assessment, developed by the United Nations Office for Disaster Risk Reduction. It emphasizes the importance of understanding disaster risk as a foundation for effective disaster risk management and sustainable develo
...
pment. The guidelines outline a structured process that includes preparing and scoping the assessment, conducting risk analysis, and using the results to inform policy and decision-making. They promote a comprehensive, multi-hazard approach that considers vulnerabilities, exposure, and capacities, while encouraging collaboration among governments, experts, and stakeholders. Overall, the document aims to help countries build stronger systems for assessing and managing risks, thereby enhancing resilience and reducing the impacts of disasters.
more
This report presents a WHO–PREZODE collaboration to develop and validate standardized indicators that assess the risk of zoonotic disease emergence by modeling pathogen circulation in animals and the risk of animal to human zoonotic spillover. The proposed indicators are intended to be actionable,
...
i.e., to reflect the impact of the implementation of a prevention strategy along the process of zoonotic pathogen emergence and over time.
more
A Global Access Framework for Country-Led.
ResponsesThis 2030 Prevention access framework focuses on one of those top-line targets, which covers primary prevention and requires that 90% of people in need of HIV prevention are using effective prevention options by 2030. This target is disaggregated
...
into 15 second-line prevention targets for specific populations and programmes.
The 2030 Prevention Access Framework presents in greater detail the milestones and actions for achieving these targets––all of which are grounded in the three priorities of the Global AIDS Strategy: country-led, resilient and sustainable HIV responses; people-focused services, and community leadership
more
The Gender Assessment Tool for National HIV Responses (Gender Assessment Tool) is intended to assist countries in assessing their HIV epidemic, context and response through an intersectional gender lens, with the aim of strengthening gender-transformative, equitable and rights-based HIV responses. T
...
he 2025 tool places greater emphasis on cost-effectiveness, alignment with national plans, integration and sustainability. Together with a new costing tool and monitoring and evaluation plan template, it is designed to inform the development of country investment cases, funding requests to the Global Fund to Fight AIDS, Tuberculosis and Malaria, and other key national opportunities.
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The Gulf CDC Technical Guide for Rapid Risk Assessments of Acute Public Health Events provides a structured, multi-sectoral approach to evaluate and manage public health threats in Gulf Cooperation Council (GCC) countries. It focuses on rapid, evidence-based assessments (within 2-5 days) to determin
...
e risk levels, propose control measures, and guide communications
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The handbook is intended as a guide and tool for anyone It focuses in particular on warehouse management and stock involved in logistics activities