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1
2nd edition. The purpose of this document is to present updated standardized protocols that P. falciparum-endemic countries can use to determine the prevalence of parasites with pfhrp2/3 gene deletions causing negative HRP2 RDT results among symptomatic falciparum patients. The findings should be us
...
ed to guide RDT selection; more specifically when to shift away from exclusive use of HRP2 to detect P. falciparum infections.
more
Clinical Pharmacology: Advances and Applications, 2025:17 29–47
Offering additional pre-exposure prophylaxis (PrEP) choices has the potential to increase uptake and effective use of PrEP, and of HIV prevention overall, as it allows people to choose a method that they prefer.
In this guideline, WHO recommends an offering long-acting injectable lenacapavir (LEN
...
) as an additional HIV prevention choice, as part of combination HIV prevention approaches. LEN, administered twice a year as PrEP, has been shown to be highly effective at reducing the risk of HIV acquisition. In this guideline, WHO also recommends using HIV rapid diagnostic tests (RDTs) for individuals initiating or continuing long-acting injectable PrEP, such as LEN and long acting injectable cabotegravir (CAB-LA). Flexible HIV testing approaches are essential for ensuring that testing does not become a barrier to accessing or continuing PrEP, including long-acting injectable options.
more
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex B
This toolkit suggests several approaches to addressing technology
access disparities. At its core is a comprehensive checklist that helps
teams systematically evaluate their current practices and identify
opportunities for improvement. This structured self-assessment
tool spans both team-level a
...
ctions and organisational responsibilities,
recognising that change must occur at multiple levels
more
HUMANITIES AND SOCIAL SCIENCES COMMUNICATIONS | (2022)9:295 | https://doi.org/10.1057/s41599-022-01312-3 .
Sub-Saharan Africa (SSA), particularly Southern and East Africa, has the highest AIDS deaths
and HIV-infected people in the world. Even though considerable effort has been made over
the yea
...
rs to study HIV transmission risk behaviours of different population groups in SSA,
there is little evidence of studies that have looked at pooled effects of associated HIV risk
factors among men, particularly in Southern Africa.
more
The findings of the report are both urgent and devastating. At the current rate of progress, by 2040 we would still have 1.9 million new HIV infections and 990,000 AIDS-related deaths in children. But if funding for HIV prevention and treatment continues to fall as current trends suggest, the world
...
could face an additional 1.1 million new HIV infections and 820,000 additional deaths by 2040. In this worst-case scenario, by 2040, three million children would acquire HIV and nearly 1.8 million would die of AIDS-related causes — the vast majority in sub-Saharan Africa. These are not statistics; they are children with dreams, families, and futures. They represent our shared humanity — and our collective failure if we do not act.
more
The handbook includes evidence-based mental health interventions, drawn from the WHO mhGAP guidelines for mental, neurological, and substance use disorders (3), particularly those listed in the UHC Compendium. Evidencebased interventions to reduce population health-related stigma and discriminatio
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n are included in the ECP in order to address the stigma experienced both by people living with mental health conditions and by those living with NTDs.
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In: Antenatal Care, Maternal Care, Under 5 Clinics, Family Planning Clinics and HIV Exposed Child Follow Up.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replaces all previous editions of the Malawi Antiretrovir
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al therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
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A Training Manual for Community Service Providers
This facilitator manual is aimed at trainers of a three-day
‘Integrating VAC prevention and response into HIV settings’
course. It is for use by all facilitators who are delivering the
training.
This training seeks to equip health workers who have contact with children in HIV settings with the knowledge and skills to better integrate violence against children (VAC) services into their work. It seeks to transmit information and skills to make them: feel comfortable talking with, providing se
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rvices and making appropriate referrals to children and their caregivers who are at risk of or experiencing violence.
This three-day training package includes ten modules to be delivered to groups of 25-30 health workers. The training is aimed at different cadres of health workers, including: nurses and midwives; clinicians; HIV counselors; medical social workers; pharmacists; community health workers, and others who are involved in children’s health care in health settings
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This document aims to provide Ministry of Health guidance on the implementation of PEP and PrEP to prevent HIV transmission and improve overall health outcomes. This comprehensive approach reflects the commitment of all involved in combating HIV and enhancing public health.
The document “Public Health Surveillance for Cholera – Guidance Document (2024)” provides practical recommendations for countries on how to design, implement, and strengthen cholera surveillance systems. Developed by the Global Task Force on Cholera Control (GTFCC), it outlines the minimum req
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uirements for detecting, confirming, reporting, and monitoring cholera cases and outbreaks.
The guidance explains the core functions of cholera surveillance, including case detection, laboratory testing (such as RDTs, culture, and PCR), routine data collection, outbreak notification, case and field investigation, data analysis, and performance monitoring. It also describes how surveillance strategies should be adapted depending on whether a country is experiencing no outbreak, clustered transmission, or community transmission.
Overall, the document aims to help countries establish adaptive, fit-for-purpose surveillance systems that enable early outbreak detection, guide timely response measures, and support long-term cholera control and elimination efforts.
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The document Integrated Disease Surveillance and Response Technical Guidelines, Booklet Four: Sections 8 and 9 (Third Edition, 2019) provides guidance for strengthening public health surveillance and response systems in the WHO African Region. It focuses on monitoring, supervision, evaluation, and f
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eedback mechanisms to improve the performance and quality of Integrated Disease Surveillance and Response (IDSR) systems. The text outlines key surveillance core functions—such as case detection, reporting, data analysis, outbreak investigation, preparedness, response, and feedback—and introduces indicators to measure system effectiveness, including timeliness, completeness, and data quality. Additionally, it discusses the implementation of electronic IDSR (eIDSR) to enhance real-time reporting and outbreak management. Overall, the booklet aims to strengthen early detection, rapid response, and health security capacity across all levels of the health system.
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The document “Strengthening the global architecture for health emergency prevention, preparedness, response and resilience” presents a report by the Director-General of the World Health Organization (WHO) to the World Health Assembly on global efforts to improve preparedness and response to heal
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th emergencies. It reviews the implementation of the Health Emergency Prevention, Preparedness, Response and Resilience (HEPR) framework and highlights lessons learned from recent crises such as COVID-19. The report describes international initiatives to strengthen global health governance, surveillance systems, laboratory networks, community protection measures, healthcare capacity and access to medical countermeasures like vaccines and diagnostics. It also discusses coordination of emergency responses, support for countries facing outbreaks or humanitarian crises, and the importance of international cooperation. In addition, the report emphasizes the need for sustainable and coordinated financing to strengthen global health security and ensure that countries can better prevent, detect and respond to future health threats.
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The text is a report from a WHO meeting that focuses on strengthening research in the field of health emergency and disaster risk management (Health EDRM). It describes how experts from different regions discussed current challenges, progress, and future priorities in improving research to better pr
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epare for and respond to health emergencies and disasters. A central theme is the need for stronger collaboration between countries, institutions, and disciplines, as well as better use of evidence to support policies and decision-making. The report also outlines key actions, such as improving data sharing, developing practical guidance for policymakers, increasing research capacity—especially in low- and middle-income countries—and ensuring that research findings are effectively translated into real-world practice. Overall, the text emphasizes global cooperation and evidence-based strategies to enhance preparedness and resilience against health threats.
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La récurrence des épidémies de la maladie à virus Ebola constitue un problème important de santé publique pour la République Démocratique du Congo. Cette situation épidémique qui sévit dans les communautés concerne toutes les couches de la population y compris dans la communauté scolair
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e. Outre la maladie à virus Ebola et la Covid-19 pouvant se transmettre facilement en milieu scolaire, certaines maladies zoonotiques parasitaires et fungiques y sont fréquemment observées chez les élèves. Il est à noter que 60% des maladies infectieuses humaines sont zoonotiques. La protection des enfants et des établissements d’enseignement s’avère particulièrement importante. Il est nécessaire de prendre des précautions pour éviter la propagation éventuelle de la COVID-19 en milieu scolaire. Cependant, il faut également veiller à ne pas stigmatiser les élèves et le personnel susceptibles d’avoir été exposés au virus
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As this report shows,
reports of child abuse and of children
witnessing violence between their
parents and caregivers have increased.
Ending violence against children is
increasingly within our reach. D
This study examines the gendered impacts of the Ebola virus disease (EVD) in Liberia in the largest outbreak of EVD ever recorded. The findings are based on an extensive two-week desk study and one-week participatory field study conducted in January 2015 in the cities of Monrovia and Buchanan in Lib
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eria
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