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This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
...
ding site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
more
World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans.
The document “Pandemic Planning Response Guide” provides guidance for organizations on how to prepare for, respond to, and recover from a pandemic. It explains what a pandemic is and emphasizes the importance of advance planning to reduce disruptions to operations. The guide presents a structure
...
d response framework based on different pandemic phases—from early alert and pre-pandemic preparation to the active pandemic phase and the recovery period afterward. For each phase, it outlines triggers, strategic actions, and practical tasks organizations should implement, such as establishing communication plans, ensuring business continuity, supporting remote work, managing supply chains, and protecting employee health and safety. In addition, the guide discusses key planning considerations like crisis communication, mental health impacts, transportation disruptions, and workforce management. Overall, the document serves as a practical template to help organizations maintain essential services and adapt their operations during a global health emergency.
more
The document “Strengthening the global architecture for health emergency prevention, preparedness, response and resilience” presents a report by the Director-General of the World Health Organization (WHO) to the World Health Assembly on global efforts to improve preparedness and response to heal
...
th emergencies. It reviews the implementation of the Health Emergency Prevention, Preparedness, Response and Resilience (HEPR) framework and highlights lessons learned from recent crises such as COVID-19. The report describes international initiatives to strengthen global health governance, surveillance systems, laboratory networks, community protection measures, healthcare capacity and access to medical countermeasures like vaccines and diagnostics. It also discusses coordination of emergency responses, support for countries facing outbreaks or humanitarian crises, and the importance of international cooperation. In addition, the report emphasizes the need for sustainable and coordinated financing to strengthen global health security and ensure that countries can better prevent, detect and respond to future health threats.
more
This guideline document is a publication of the National AIDS & STI Control Program, Ministry of Health
Kenya
WHO's Department for HIV, Tuberculosis, Hepatitis and Sexually Transmitted Infections (STIs) has consolidated all existing normative guidance on STIs into a single publication. Structured around 10 chapters that follow the STI prevention and care cascade, the handbook covers primary prevention, synd
...
romic management and asymptomatic case identification, diagnostics, treatment, partner management, surveillance, service delivery, and integration within primary health care, community-based clinics, or other platforms (HIV, sexual health, antenatal clinics, etc).
more
This document consolidates, for the first time, WHO recommendations on the prevention, testing, treatment and monitoring of hepatitis B and C, and includes testing strategies for hepatitis D. Drawing on a decade of evidence-based guidance issued between 2015 and 2025, it provides a single, practical
...
handbook to support global progress toward eliminating viral hepatitis by 2030.
The document also highlights simplified service delivery models that promote decentralization, integration with primary care and related programmes such as HIV and tuberculosis, as well as task sharing and differentiated care to expand access and improve efficiency. It further underscores the need for robust data and monitoring systems to support effective programme implementation.
more
Female genital mutilation (FGM) is a human rights violation deeply rooted in gender inequality and discrimination. FGM violates various human rights under international human rights law including, among others, the rights to equality, life and health and the rights to be free from discrimination, to
...
rture and cruel, inhuman and degrading treatment. The failure by States to end this harmful practice against women and girls is a violation of States’ obligations to respect, protect and fulfil the enjoyment of all human rights. These obligations are accompanied by certain human rights accountability mechanisms that are critical in holding States to account for implementing their international and regional human rights obligations and commitments
more
The decriminalization of drug use and possession for personal use, when implemented effectively, is a critical element in a human rights and public health-based HIV response. The group of countries that have adopted decriminalization models spans all continents. This document brings together differe
...
nt approaches to and experiences of decriminalization of drug use and possession for personal use and provides recommendations for countries to ensure an enabling environment for the HIV response.
more
The World report on promoting the health of refugees and migrants: Monitoring progress on the WHO global action plan provides the first global baseline for assessing implementation of the 2019-2030 WHO Global Action Plan on Promoting the Health of Refugees and Migrants (GAP). Building on the 2022 Wo
...
rld report on the health of refugees and migrants, it examines how countries are integrating refugee and migrant health into broader public health, migration governance, development, and universal health coverage (UHC) agendas.
more
The document presents a strategic framework by the World Health Organization for managing risks related to emergencies and disasters in the health sector. It highlights that such events (such as epidemics, natural disasters, or conflicts) have major impacts on health, healthcare systems, and societa
...
l development. The framework proposes a comprehensive and proactive approach based on prevention, preparedness, response, and recovery, while emphasizing the importance of collaboration across different sectors and stakeholders. Its main objective is to reduce health risks, strengthen the resilience of communities and health systems, and improve health security at the global level.
more
Artificial intelligence for tuberculosis control: a scoping review of applications in public health
Menon, S.; and K. Ghislein Kuro
(2025)
J Glob Health. 2025;15:04192. This scoping review highlights the potential of AI-driven predictions in national TB programmes to enhance diagnostics, track trends, and strengthen public health surveillance. While promising for reducing transmission and support-
ing TB care in low-resource settings,
...
these models require large-scale validation to ensure real-world applicability, especially for high-risk groups
more
The GHEC framework is designed to provide guiding principles for standardizing health emergency workforce structures to strengthen the capacity of countries in responding to health emergencies, and to enhance collaboration between countries by better connecting regional and global surge response mec
...
hanisms, facilitating information exchange, and improving access to expertise and human response capacity at times of need.
This is the first version of the GHEC framework and is intended to be updated as experience is gained with its implementation and adaptation.
more
This tool enables a rapid, systematic review of pharmacy curricula at the national or institutional level to evaluate their robustness in delivering the expected content and competencies. It can also assist institutions in designing strategies to strengthen AMR curricular content, and to facilitate
...
structured, periodic dialogue on AMR and infection-related competencies among pharmacy faculty and other relevant stakeholders. A pharmacy curriculum that comprehensively integrates AMR content will help ensure that future pharmacists have the knowledge, skills, and attitudes needed to address AMR effectively in both clinical practice and public health.
more
This guidance addresses one type of generative AI, large multi-modal models (LMMs), which can accept one or more type of data input and generate diverse outputs that are not limited to the type of data fed into the algorithm. It has been predicted that LMMs will have wide use and application in heal
...
th care, scientific research, public health and drug development. LMMs are also known as “general-purpose foundation models”, although it is not yet proven whether LMMs can accomplish a wide range of tasks and purposes.
more
A Global Access Framework for Country-Led.
ResponsesThis 2030 Prevention access framework focuses on one of those top-line targets, which covers primary prevention and requires that 90% of people in need of HIV prevention are using effective prevention options by 2030. This target is disaggregated
...
into 15 second-line prevention targets for specific populations and programmes.
The 2030 Prevention Access Framework presents in greater detail the milestones and actions for achieving these targets––all of which are grounded in the three priorities of the Global AIDS Strategy: country-led, resilient and sustainable HIV responses; people-focused services, and community leadership
more
The COVID-19 pandemic is the most severe health crisis in a century, exposing deep gaps in the world’s defences against epidemics and pandemics, and teaching us painful
lessons. One of them is that in our intimately connected world, pathogens can spread around the world very quickly, demanding sy
...
stems that can respond equally quickly. That
includes systems to facilitate the rapid exchange of biological materials and related data, to support the development of guidance and medical countermeasures including vaccines,
tests and treatments.
Based on the lessons that COVID-19 was teaching us, World Health Organization announced the
establishment of the WHO BioHub System at the height of the pandemic, in January 2021. Developed collaboratively and iteratiely with the active engagement of Member States and other partners, the BioHub System has now been through a pilot-testing phase that has demonstrated its value as a multilateral model and a tangible asset that Member States can harness to bolster their preparedness against emergent viral threats.
more
The ultimate aim of the framework is to assist the user to thoughtfully, deliberately, ethically, and rationally determine whether or not the delivery of one or more vaccines to specific target populations during the acute phase of an emergency would result in an overall saving of lives, a reduction
...
in the population burden of disease, and generally more favourable outcomes than would otherwise be the case.
more
It provides comprehensive guidance for logistics planners in humanitarian responses to pandemics, covering preparedness, response strategies, assessment methodologies, and operational planning.
This guidance document, titled 'Preparedness Enabler's Guide (PEG)', published in May 2023, aims to promote effective and sustainable localization in humanitarian preparedness through insights and practical tools derived from the Global Logistics Cluster's experience.
