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Publication Years
2004
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Category
2371
416
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234
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57
1
Toolboxes
864
555
432
357
272
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1
This publication aims to provide updated guidance on the specific use of yellow fever laboratory assays in the context of surveillance to be used across the Global Yellow Fever Laboratory Network for disease surveillance. In the recent years, new commercial assays became available
...
and are now recommended for use by WHO and this publication will support national program on the use of compound laboratory assays as per the most recent recommended testing algorithms. This piece is aligned with the elimination effort set in the comprehensive global strategy to eliminate yellow fever epidemics (EYE) strategy 2017-2026 and where its advisory laboratory technical working group actively contributed to its development. The target audiences are policy-makers and health workers.
more
WHO has published the first-ever guidance on the clinical management of diphtheria. The only previously available guidance was an operational protocol. The new guidance followed the rigorous process for developing guidance at WHO.
It addresses the use of Diphtheria Antitoxin (DAT) in the treatmen
...
t of diphtheria. There is a worldwide shortage of DAT and evidence based recommendations on the use of DAT were requested by many Member States.
The guidance also includes new recommendations on antibiotics. In patients with suspected or confirmed diphtheria, WHO recommends using macrolide antibiotics (azithromycin, erythromycin) rather than penicillin antibiotics.
This clinical practice guideline has been rapidly developed recognizing the global increase in diphtheria outbreaks. Outbreaks of diphtheria in Nigeria, Guinea and neighbouring countries in 2023 have highlighted the urgent need for evidence-based clinical practice guidelines for the treatment of diphtheria. Given the sporadic nature of outbreaks, many clinicians in the affected regions have never managed acute diphtheria and its related complications. Diphtheria remains a neglected disease and vaccination is the top priority. At the same time, for patients with diphtheria, access to antibiotics, DAT and supportive care can be lifesaving.
more
This trainer toolkit is a guide for Neglected Tropical Diseases (NTD) program implementers in Nigeria to train primary health care health workers to diagnose and provide care for women and girls wi
...
th symptoms of female genital schistosomiasis (FGS). It has been developed based on a pilot study in Ogun State where 22 health facilities were trained on using the FGS tools. The trainer guide should be used alongside the ‘Health Worker Training Guide for managing FGS within primary health care’. Trainers should familiarise themselves with this manual before the training to ensure that all aspects of the training are conducted effectively.
more
The ILO has joined forces with Gallup to carry out a groundbreaking global survey covering 50 countries that sheds further light on the causes of the persistence of HIV-related stigma and discrimination in the world of work.
NOVEMBER 2012
This document serves as an update to “Out of the Dark”, a report published by MSF in October 2011, highlighting the need to prioritise the long-neglected area of paediatric tuberculosis (TB). This update will outline the key improvements
...
and setbacks—the ‘highlights’ and ‘lowlights’—that have occurred over the last year.
more
With about 24 million of Yemen’s 30 million people in need of some form of assistance, the United Nations calls Yemen the world’s worst humanitarian crisis. Cholera and other disease outbreaks are common, malnutrition is widespread, water is sca
...
rce, and the healthcare system is crumbling, with only half of the country’s 5,000 or so health facilities fully operational and with massive medical supply and staff shortages. In August 2020, the UN warned the country was again on the brink of full-scale famine.
more
August 2020.
In December 2018, the President launched the UHC pilot covering four strategically selected counties-Isiolo, Kisumu, Machakos and Nyeri. It isplanned that by the year 2022, all persons in Kenya will be able to use the
...
essential services they need for their health and wellbeing through a single unified benefit package, without the risk of financial catastrophe. Essential health products are considered an integral part of UHC andare an indispensable element for delivery ofservices andare also a requirement for qualitycare. Despite this realization, a review of the UHC pilot in September 2019 established that whereas the Kenya Medical Supplies Authority (KEMSA) was able to fill up to 80% of pharmaceutical items, the order fill rate for medical supplies was less than 50%for level 2 and 3 facilities and as low as 30%for level 4 and 5 facilities.
more
Int. J. Environ. Res. Public Health 2021, 18(24), 13339; https://doi.org/10.3390/ijerph182413339
The climate crisis threatens to exacerbate numerous climate-sensitive health risks, including heatwave mortality, malnutrition from reduced crop yields, water-
...
and vector-borne infectious diseases, and respiratory illness from smog, ozone, allergenic pollen, and wildfires. Recent reports from the Intergovernmental Panel on Climate Change stress the urgent need for action to mitigate climate change, underscoring the need for more scientific assessment of the benefits of climate action for health and wellbeing.
more
In 2019, the Task Force on Fiscal Policy for Health concluded that taxes on tobacco, alcohol, and sugar-sweetened beverages were a highly effective but greatly underused policy tool to reduce consumption, save lives,
...
and raise domestic resources. The Task Force estimated that if all countries increased their excise taxes to raise prices by 50 percent, over 50 million premature deaths could be averted worldwide over the next 50 years while
raising over USD 20 trillion of additional revenue. Since the Task Force first convened, the world has faced a “polycrisis,” including a global pandemic, an economic recession, and the outbreak of wars in Europe and the Middle East. Against this backdrop, the world has also experienced prolonged health and fiscal crises. Health systems, weakened by the COVID-19 pandemic, lack sufficient financing to rebuild and respond to the surging noncommunicable diseases epidemic caused by uncontrolled risk factors such as tobacco, alcohol, and sugar consumption. Opportunities to raise domestic resources are limited and debt burdens have squeezed budgets. The period from 2019 to 2027 risks becoming a “lost decade” for health and social policies, with 110 countries facing little prospect of any
ability to raise government revenues beyond current levels. In this paper, we describe the current health and fiscal crises and review the contribution that health taxes could make in turning around this dire situation. We conclude that taxes on tobacco, alcohol, and
sugar-sweetened beverages are an ideal policy solution—good for the budget and good for health. These taxes are relatively quick to implement, and, unlike other taxes, do not put economic growth at risk—a vital benefit in the current era.
more
Designed for trainers of health workers, this manual offers skills-building sessions on developing more “male-friendly” health services. Utilizing participatory and experiential activities, the manual examines attitudinal
...
and structural barriers that inhibit men from seeking HIV and AIDS services (both from the client and the provider perspectives), as well as strategies for overcoming such barriers. The manual is designed for all workers in a health care system—frontline staff, clinicians, and administrative, operational, and outreach workers.
more
Nutrition Cluster Handbook
recommended
Josephine Ippe, Diane Holland, Leah Richardson, et al.
The Global Nutrition Cluster, UNICEF
(2013)
C1
The purpose of the handbook is to provide those involved in nutrition coordination with relevant tools, guidance, information and resources to support their roles in facilitating predictable, coordinated a
...
nd effective preparation for, and responses to, nutrition needs in humanitarian emergencies. Rather than being prescriptive, the handbook aims to raises key issues encountered to date.
more
Rapport de mission, 10-14 juillet 2017
Madagascar a conduit la mission d’évaluation externe conjointe de la mise en œuvre des capacités du Règlement Sanitaire International (2005) du 10 au 14 juillet 2017. ...
Pour disposer de capacités fonctionnelles et pérennes, le pays devra ren ... forcer encore d’avantage l’ensemble des 19 domaines techniques en mettant en œuvre les recommandations ci-dessous. A cet égard, il est primordial de mettre l’accent sur : i) l’élaboration et l’application de cadres législatifs, propices à l’application du Règlement sanitaire international (2005) et à la gestion des risques de catastrophe ; ii) la coordination multisectorielle dans la mise en œuvre du Règlement sanitaire international (2005) ; iii) le renforcement des capacités du point focal RSI ainsi que sa relation avec tous les secteurs clés dans la prévention, la détection et la riposte ; iv) la rédaction et la mise en œuvre des procédures requises en tenant compte de l’approche englobant l’ensemble des menaces ; et v) l’analyse et la cartographie des risques d’épidémies et de catastrophes, en utilisant une approche multisectorielle qui permettra d’actualiser et d’établir des plans de préparation et de riposte contre les zoonoses, les maladies infectieuses émergentes et ré-émergentes et les facteurs de risque environnementaux en utilisant l’approche « Une seule santé ». more
Madagascar a conduit la mission d’évaluation externe conjointe de la mise en œuvre des capacités du Règlement Sanitaire International (2005) du 10 au 14 juillet 2017. ...
Pour disposer de capacités fonctionnelles et pérennes, le pays devra ren ... forcer encore d’avantage l’ensemble des 19 domaines techniques en mettant en œuvre les recommandations ci-dessous. A cet égard, il est primordial de mettre l’accent sur : i) l’élaboration et l’application de cadres législatifs, propices à l’application du Règlement sanitaire international (2005) et à la gestion des risques de catastrophe ; ii) la coordination multisectorielle dans la mise en œuvre du Règlement sanitaire international (2005) ; iii) le renforcement des capacités du point focal RSI ainsi que sa relation avec tous les secteurs clés dans la prévention, la détection et la riposte ; iv) la rédaction et la mise en œuvre des procédures requises en tenant compte de l’approche englobant l’ensemble des menaces ; et v) l’analyse et la cartographie des risques d’épidémies et de catastrophes, en utilisant une approche multisectorielle qui permettra d’actualiser et d’établir des plans de préparation et de riposte contre les zoonoses, les maladies infectieuses émergentes et ré-émergentes et les facteurs de risque environnementaux en utilisant l’approche « Une seule santé ». more
Following the encouraging initial results of the pilot project, the Ministry of Health is committed to increasing access to MDR-TB diagnosis, treatment and care. An expansion plan for the programmatic management of drug-resistant TB has been develop
...
ed and forms part of the Five Year National Strategic Plan for TB Control, 2011-2015. The long-term goals of the MDR-TB expansion plan are threefold:
1. Diagnosis of MDR-TB in all groups of patients at risk for MDR-TB
2. Diagnosis of MDR-TB in all HIV-infected TB patients
3. MDR-TB treatment for all patients diagnosed with MDR-TB under WHO-endorsed treatment protocols more
1. Diagnosis of MDR-TB in all groups of patients at risk for MDR-TB
2. Diagnosis of MDR-TB in all HIV-infected TB patients
3. MDR-TB treatment for all patients diagnosed with MDR-TB under WHO-endorsed treatment protocols more
Prepared as an outcome of ICMR Expert Group on Immunophenotyping of Hematolymphoid Neoplasms | Coordinated by Division of Non Communicable Diseases | This document addresses on various issue related to good quality practices in laboratory work up of flow cytometric immunophenotyping
...
and will be of use to pathologists, cytometrists, hematologists, technologists and scientists working in this field.
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The guidelines reiterate that the general principles of ethics for biomedical research involving human participants shall also be applicable. In addition, the guidelines specify unique provisions for stem cells, because of their inherent property for unlimited proliferation, differentiation to cells
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of the germ layers, oncogenic potential, unrecognised toxicities and possible involvement in pre-implantation stages of human development. The guideline therefore focuses on: 1. Monitoring mechanism and regulatory pathway for basic, clinical research and product development based on categories of research and level of manipulation. 2. Procurement of gametes, embryos and somatic cells for derivation and propagation of any stem cell lines, their banking and distribution. 3. Other important areas like international collaboration, exchange of cell/lines and education for stakeholders and advertisement.
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Le Bénin à l’instar des autres pays d’Afrique subsaharienne, fait face à une épidémie généralisée du VIH qui est actuellement au centre des préoccupations de santé publique et de développement. De 2002 à 2006, la prévalence nationale est stabilisée autour de 2% grâce à une améli
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oration de la prise en charge des PVVIH, une augmentation du nombre de patients sous ARV, et un renforcement du partenariat avec la société civile y compris le secteur privé. En 2007, on a observé une légère inflexion à 1,7% de la prévalence.
Les conséquences multiples de l’infection par le VIH ont très vite imposé la nécessité d’une prise en charge globale des personnes infectées et affectées. Les interventions sont désormais multiples et intégrées allant de la prévention à la prise en charge en passant par le conseil - dépistage (CD).
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Profiles of Peripheral CD4+T Cells Count during Antiretroviral Treatment in Senegalese Adults Infected by HIV: Impact of Therapeutic Associations
Niang M. S., R. Derwiche, B. Mbengue
Journal of Immunology, Infection & Inflammatory Diseases
(2017)
CC
Thirty-three years after its discovery, the Human Immunodeficiency Virus (HIV), responsible for the AIDS pandemic, remains a major public health problem despite advanced researches providing better diagnostic and therapeutic tools. The virus targets
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especially CD4+ T cells, leading to deficiency of the immune system and altering therefore defense against infections and cancer cells. Antiretroviral
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A comprehensive briefing by Half of Syria
April 2020
A comprehensive briefing on the critical challenges of the COVID-19 pandemic to Syrians, as reported by Syrian civil society organisations. These challenges have been collated following extensive interviews with the teams of member
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and partner organisations working in the field in various sectors: health, child care, education, women’s empowerment, media and culture, research, human rights and accountability, relief and social services, and local governance.
This comprehensive briefing also include concrete recommendations formulated by the Syrian civil society.
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These WHO interim recommendations on the use of the Astra Zeneca – Oxford University AZD1222 vaccine against Covid-19 were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence s
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ummary included in the background document referenced below.
This document has been updated: Version 15 March 2022.
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The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR
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-TB. The WHO Operational Handbook on Tuberculosis, Module 4: Treatment - Drug-Resistant Tuberculosis Treatment provides practical guidance on how to put in place the recommendations at the scale needed to achieve national and global impact.
The operational handbook provides practical information and tools that complement the recommendations in the guidelines. The strategies described in the operational handbook are based on the latest WHO recommendations which were formulated by Guideline Development Groups using the GRADE approach. In many cases however, the recommendations in their current form lacked sufficient clinical and programmatic detail, which is important for implementation. This operational handbook complements the guidelines with practical advice based on best practices and knowledge from the fields such as pharmacokinetics, pharmacodynamics, microbiology, pharmacovigilance and clinical and programmatic management.
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