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Cystic fibrosis (CF) was earlier thought to be a disease prevalent in the West among Caucasians. However, quite a number of recent studies have uncovered CF cases outside of this region, and reported hundreds of unique and novel variant forms of CFTR. Here, we discuss the evidence of CF in parts of
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the world earlier considered to be rare; Africa, and Asia. This review also highlighted the CFTR mutation variations and new mutations discovered in these regions. This discovery implies that the CF data from these regions were earlier underestimated. The inadequate awareness of the disease in these regions might have contributed towards the poor diagnostic facilities, under-diagnosis or/and under-reporting, and the lack of CF associated health policies. Overall, these regions have a high rate of infant, childhood and early adulthood mortality due to CF. Therefore, there is a need for a thorough investigation of CF prevalence and to identify unique and novel variant mutations within these regions in order to formulate intervention plans, create awareness, develop mutation specific screening kits and therapies to keep CF mortality at bay.
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2016 Ghana Malaria Indicator Survey (GMIS)
General fact sheet in booklet form about the 2014-2015 Demographic and Health Survey conducted in Rwanda. The 2014-15 Rwanda Demographic and Health Survey (RDHS) provides data for monitoring the health situation of the population in Rwanda. The 2014-15 RDHS is the 5th Demographic and Health Survey c
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onducted in the country. The survey is based on a nationally representative sample. It provides estimates at the national and provincial levels, as well as for urban and rural areas, and for some, at the district level.
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Accessed on 02.02.2020
Child marriage is a serious Violation of human Rights and a severe form of child abuse, and disproportionately affects girls.
As Russia's invasion of Ukraine progresses, the civilian population and the Armed Forces face enormous challenges. It is unsurprising that people's mental health deteriorate in such conditions. This Issue Brief provides publications and informative resources highlighting the impact on Mental Health.
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This factsheet shows that type 2 diabetes in older age groups is high and growing rapidly in many parts of the world, but can be managed inexpensively with early diagnosis, treatment and information.
Key Populations Brief
Accessed November 2017
Diabetes poses an increasingly serious health challenge in Africa. Currently, 25 million adults aged 20–79 are living with diabetes, and this figure is projected to increase by 142% to 60 million by 2050 — the highest regional increase worldwide. However, 73% of cases remain undiagnosed, and hea
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lthcare spending is the lowest worldwide at just USD 10 billion (1% of global expenditure). In 2024, diabetes caused 216,000 deaths and had a significant impact on maternal health, affecting 1 in 7 births due to hyperglycaemia during pregnancy. Nigeria, Tanzania and the Democratic Republic of the Congo have the highest case loads. Without urgent intervention, the diabetes burden will continue to grow, putting further strain on already limited health systems.
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Accessed August 2018
