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Issue Brief: Neglected Tropical Diseases Part 2
recommended

MEDBOX Team (2025) CC
In this subsequent part of the issue brief on the NTD Toolbox you will learn about general strategies, roadmaps, key treatment guidelines, reports, and training material on Dengue & Chikungunya, Human African Trypanosomiasis and Leprosy.
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Evaluation of serum-based real-time PCR to detect Schistosoma mansoni infection before and after treatment

Fuss, A.; H. D. Mazigo and A. Mueller (2020) CC
Infectious Diseases of Poverty (2020) 9:74 To detect acute schistosomiasis, low-intensity infections, or to verify the success of treatment with praziquantel, highly sensitive test methods are required. The aim of this study was therefore to demonstrate the performance of Schistosoma mansoni spec ... more
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Health Workers Training Guide for Managing Female Genital Schistosomiasis (FGS) in Primary Health Care

Countdown Calling Time on Neglected Tropical Diseases Sightsavers (2021) CC
This trainer toolkit is a guide for Neglected Tropical Diseases (NTD) program implementers in Nigeria to train primary health care health workers to diagnose and provide care for women and girls with symptoms of female genital schistosomiasis (FGS). It has been developed based on a pilot study in ... more
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Schistosomiasis Module Diploma

The Carter Center (2005) CC
Diploma Program For the Ethiopian Health Center Team
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Chagas Disease Drug Discovery in Latin America

Oliveira, R.G. de.; L.R. Cruz; M.C. Mollo, (2021) CC
A Mini Review of Antiparasitic Agents explored between 2010-2021. Frontiers in Chemistry 9:771143
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Clinical features of Chagas disease progression and severity

Nunes, M.C.P.; C. Bern, E.H. Clark, (2024) CC
The Lancet Regional Health Americas Volume 37100832 September 2024
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Brief overview of Ebola disease with a focus on Sudan virus disease (SVD)

World Health Organization WHO (2025) C_WHO
Sudan virus disease is a severe, often fatal illness affecting humans and other primates that is due to Orthoebolavirus sudanense (Sudan virus), a viral species belonging to the same genus of the virus causing Ebola virus disease. This webinar will provide an overview of the current outbreak of Suda ... more
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Prevalence of clinical forms of Chagas disease: a systematic review and meta-analysis – data from the RAISE study

Nasciemento, B.R.; (2024) CC
The Lancet Regional Health - Americas 2024;30: 100681 Published Online 3 February 2024 https://doi.org/10.1016/j.lana.2024.100681
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Retrospect, advances and challenges in Chagas disease diagnosis: a comprehensive review

Schijmann, A.G.; J. Alonsa-Padilla, C. Britto, (2024) CC
The Lancet Regional Health - Americas 2024;36: 100821 https://doi.org/10.1016/j.lana.2024.100821
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Worldwide prevalence of chagas cardiomyopathy—an analysis from the global burden of disease dataset

Mannan Khan Minhas, A.; (2024) CC
Infection https://doi.org/10.1007/s15010-024-02408-5
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Infection prevention and control and water sanitation and hygiene in health facilities during mpox disease outbreaks: rapid assessment tool, user guide

World Health Organization WHO (2025) CC
The rapid assessment tool (RAT) is meant to assess health facilities within mpox-affected areas that have at least one inpatient bed. Depending on time and resources available, certain facilities may be prioritized during an mpox outbreak. The RAT evaluates 16 infection prevention and control (IPC) ... more
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Cholera Outbreak in Haiti. Situation Report, n. 8 (13 March 2024)

Pan American Health Organization (PAHO) (2024) C_WHO
The report provides an update on the cholera outbreak in Haiti as of January and February 2024. A total of 79,411 suspected cases have been reported, with 4,608 confirmed cases and 1,172 deaths across all 10 departments. The most affected regions include Ouest, Centre, Artibonite, and Nord, with chi ... more
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Buruli Ulcer: Advances in Understanding Mycobacterium ulcerans Infection

Walsh, D.S.; F. Portaels, W.N. Meyers, et al. (2011) CC
Dermatologic Clinics Volume 29, Issue 1p1-8January 2011
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Formulation and Stability of a 1% Clarithromycin-Based Topical Skin Cream: A New Option to Treat Buruli Ulcers?

Sebti, M.; et al. (2024) CC
Pharmaceuticals 2024, 17(6), 691; https://doi.org/10.3390/ph17060691
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Treating Buruli Ulcer

Médecines sans Frontièrs MSF (2013) CC
A review of prospects for existing antibiotics ad new therapeutics
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BuDb: A Curated Drug Discovery Database for Buruli Ulcer

Kwofie, S.K.; et al. (2022) CC
Journal of Computational Biophysics and ChemistryVol. 22, No. 01, pp. 31-41 (2023)
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Report of the fifth annual meeting of the network of Buruli ulcer PCR laboratories in the WHO African Region, Accra, Ghana, 23-25 October 2023

World Health Organization WHO (2024) C_WHO
The aim of the meeting was to broaden the network’s initiatives. Preliminary work involved integrating laboratory testing for skin NTDs other than Buruli ulcer, such as cutaneous leishmaniasis, mycetoma, leprosy and yaws, while extending the network’s reach to encompass additional laboratories.
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Human African Trypanosomiasis (Sleeping Sickness). The Road to Elimination Revisited—Achievements and Remaining Challenges

Burri, E. MDPI (2020) CC
Printed Edition pdf
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PICO questions, EtD tables, GDG recommendations

World Health Organization WHO (2024) C_WHO
WHO Guidelines for the Treatment of Human African Trypanosomiasis. Web Annex B
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Human African trypanosomiasis cases diagnosed in non-endemic countries (2011– 2020)

Franco. J.R.; G. Cecchi, G. Priotto, et al. (2022) CC
PLoS Negl Trop Dis 16(11): e0010885. https://doi.org/10.1371/journal.pntd.0010885 HAT diagnosis in non-endemic countries is rare and can be challenging, but alertness and surveillance must be maintained to contribute to WHO’s elimination goals. Early detection is particularly important as it co ... more