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Chikungunya as a paradigm for emerging viral diseases: Evaluating disease impact and hurdles to vaccine development

Rezza G., Weaver S.C. PLOS Neglected Tropical Diseases (2019) C2
Chikungunya fever (CHIKF) is an emerging infectious disease caused by an alphavirus transmitted by Aedes spp. mosquitoes. Because mosquito control programs are not highly efficient for outbreak containment, vaccines are essential to reduce the burden of disease. Although no licensed vaccine against ... more
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Answers to common questions about the Ebola prevention marklate study.

Ministry of Health & Sanitation, Sierra Leone (2015)
Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE)
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Covaxin

Bharat Biotech (2021) CC
COVAXINTM, India's indigenous COVID-19 vaccine by Bharat Biotech is developed in collaboration with the Indian Council of Medical Research (ICMR) - National Institute of Virology (NIV). The indigenous, inactivated vaccine is developed and manufactured in Bharat Biotech's BSL-3 (Bio-Safety Level 3) h... more
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Covid-19 - living NMA initiative

World Health Organization WHO, et al. (2021) C_WHO
As of January 20, 2021 the Covid-19 - living NMA initiative collected 150 RCTs and 36 non-randomised studies of vaccines from the ICTRP. 93 of these trials are recruiting patients.
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WHO Guide for Rabies Pre and Post Exposure Prophylaxis in Humans

World Health Organization WHO (2014) C_WHO
WHO strongly recommends discontinuation of the nerve tissue vaccine, and replacement with modern concentrated and purified cell culture derived vaccines (CCDV) and embryonated eggbased rabies vaccines. These vaccines must comply with WHO criteria for potency and innocuity following satisfactory ass... more
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Integrating Clinical Research into Epidemic Response: The Ebola Experience

Gerald Keusch, Keith McAdam, Patricia Cuff, Michelle Mancher, and Emily R. Busta National Academies of Sciences, Engineering, and Medicine (2017) C1
The 2014–2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Repub... more
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Chikungunya virus: A general overview

Galán-Huerta K.A., Rivas-Estilla A.M., Fernández-Salas I. et al (2015) C2
Chikungunya virus (CHIKV) is a re-emerging mosquito borne alphavirus responsible for the recent outbreak in the Americas. Immunologically naïve population in the Americas favors the spread of epidemics. Chikungunya fever is characterized by an abrupt febrile illness, polyarthralgia and maculopapul... more
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Human African trypanosomiasis - General Information

Büscher P., Cecchi G., Jamonneau V. et al World Health Organisation (WHO) (2017) C2
Human African trypanosomiasis (HAT), also called sleeping sickness, is a parasitic infection that almost invariably progresses to death, unless treatment is provided. HAT caused devastating epidemics during the 20th century. Thanks to sustained and coordinated efforts during the past 15 years the nu... more
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Consortium du Centre Africain pour le Contrôle et la Prévention des Maladies (CACM) pour les essais cliniques sur le vaccin contre la COVID-19 (CONCVACT)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
La stratégie continentale commune africaine pour COVID-19 est sous-tendue par la nécessité de limiter la transmission, de prévenir les décès et de réduire les dommages associés. La participation des nations africaines aux essais cliniques est une étape essentielle pour garantir la productio... more
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Vaccines
recommended

Kamradt, T., and B.S. Kamps (2021) CC
COVID Reference 23 May 2021
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COVID-19 Vaccine Resource Center
recommended

New England Journal of Medicine (2021) C1
A collection of resources on Covid-19 vaccines, including frequently asked questions, continuing medical education, published research, and commentary.
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Déclaration sur l’efficacité du vaccin COVID-19 d’AstraZeneca (ChAdOx1 nCoV-19) contre les variants du SARS-CoV-2
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1
On the 9 February 2021, Africa CDC convened a special session of the Africa Task Force for COVID-19 to review existing data and evidence and recommend
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Frequently Asked Questions (FAQs) about COVID-19 Candidate Vaccines and Access Mechanisms. Version 3, 6 January 2021

Pan American Health Organisation PAHO (2021) C_WHO
Will COVID-19 vaccines be safe? Will all the COVID-19 candidate vaccines be successful? What are the different phases a vaccine must go through to be approved? This document provides responses to the most frequently asked questions about candidate vaccines and access to COVID-19 vaccination.
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COVID-19 vaccines - will they be safe?

World Health Organization WHO (2020) C_WHO
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Coronavirus: India approves vaccines from Bharat Biotech and Oxford/AstraZeneca

BBC (2020) CC
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The Top COVID-19 Vaccine Myths Spreading Online

Gregory, J. NewsGuard (2021) CC
Scientists and researchers managed to produce vaccines to protect against COVID-19. Vaccine candidates have recently been approved in some countries and are in the approval process in others, yet misinformation about the safety and effects of any future vaccine is already threatening its rollout. In... more
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Mythes & COVID-19 Vaccins
recommended

Mauder, S.; and P. Reijer (2021) CC
MEDBOX Dossier no. 16. 28 Sept 2021. De nombreuses études ont montré l'efficacité de la vaccination contre le COVID-19 et le fait qu'elle protège contre les maladies graves. maladie grave. Un taux de vaccination élevé est nécessaire pour combattre la pandémie dans le monde entier. En raiso... more
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Statement on the Efficacy of the AstraZeneca COVID-19 Vaccine (ChAdOx1 nCoV-19) against the SARS-CoV-2 Variants
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1
On the 9 February 2021, Africa CDC convened a special session of the Africa Task Force for COVID-19 to review existing data and evidence and recommend
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Nota Conceitual para o Consórcio do África CDC para Ensaios Clínicos para Vacina da COVID-19 (CONCVACT)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
A Estratégia Conjunta Continental Africana para a COVID-19 é sustentada pela necessidade de limitar a transmissão, prevenir mortes e reduzir os danos associados. A participação das nações africanas em ensaios clínicos é um passo essencial para garantir que sejam gerados dados suficientes so... more
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Vacunas
recommended

Kamradt, T., B.S. Kamps J. García-Rosales Delgado (2021) CC
COVID Reference 23 May 2021